All Outputs (2)

Nicotinamide, neural cells, and Parkinson’s disease: exploring nicotinamide’s effects on proliferation, neuronal differentiation, and neuroprotection within in vitro models (2021)
Thesis
Green, E. L. Nicotinamide, neural cells, and Parkinson’s disease: exploring nicotinamide’s effects on proliferation, neuronal differentiation, and neuroprotection within in vitro models. (Thesis). Keele University. https://keele-repository.worktribe.com/output/419491

Parkinson’s disease (PD) is characterised by motor symptoms caused by degeneration of dopaminergic neurons in the substantia nigra. The cause remains elusive and current treatments cannot halt or reverse progression. This thesis explores the effects... Read More about Nicotinamide, neural cells, and Parkinson’s disease: exploring nicotinamide’s effects on proliferation, neuronal differentiation, and neuroprotection within in vitro models.

Characterising microglial activation: refinement and validation of primary in vitro models (2019)
Thesis
Al-Shaheeb, S. Characterising microglial activation: refinement and validation of primary in vitro models. (Thesis). Keele University. https://keele-repository.worktribe.com/output/413772

Background: Neuroinflammation is common to many neurodegenerative conditions and is principally mediated by microglia. Microglia maintain homeostasis, respond to trauma/infection and can promote repair. This is achieved by switching between surveilla... Read More about Characterising microglial activation: refinement and validation of primary in vitro models.