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Influence of a Dy overlayer on the precessional dynamics of a ferromagnetic thin film (2013)
Journal Article
Marcham, M. K., Yu, W., Keatley, P. S., Shelford, L. R., Shafer, P., Cavill, S. A., …Hicken, R. J. (2013). Influence of a Dy overlayer on the precessional dynamics of a ferromagnetic thin film. Applied Physics Letters, 102(6), 062418. https://doi.org/10.1063/1.4792740

Precessional dynamics of a Co50Fe50(0.7)/Ni90Fe10(5)/Dy(1)/Ru(3) (thicknesses in nm) thin film have been explored by low temperature time-resolved magneto-optical Kerr effect and phase-resolved x-ray ferromagnetic resonance measurements. As the tempe... Read More about Influence of a Dy overlayer on the precessional dynamics of a ferromagnetic thin film.

Preclinical evaluation of statins as a treatment for ovarian cancer (2013)
Journal Article
Robinson, E., Nandi, M., Wilkinson, L. L., Arrowsmith, D. M., Curtis, A. D., & Richardson, A. (2013). Preclinical evaluation of statins as a treatment for ovarian cancer. Gynecologic Oncology, 129(2), 417-424. https://doi.org/10.1016/j.ygyno.2013.02.003

Objective To evaluate the potential for statins to treat ovarian cancer. Methods The sensitivity of 7 ovarian cancer cell lines to either statins or statins combined with either carboplatin or paclitaxel was assessed using monolayer cultures. Se... Read More about Preclinical evaluation of statins as a treatment for ovarian cancer.

Poly (3-Hydroxybutyrate-co-3-Hydroxyhexanoate)/Collagen Hybrid Scaffolds for Tissue Engineering Applications (2013)
Journal Article
Lomas, A. J., Webb, W. R., Han, J., Chen, G., Sun, X., Zhang, Z., …Forsyth, N. R. (2013). Poly (3-Hydroxybutyrate-co-3-Hydroxyhexanoate)/Collagen Hybrid Scaffolds for Tissue Engineering Applications. Tissue Engineering Part C: Methods, 19(8), 577-585. https://doi.org/10.1089/ten.tec.2012.0457

The benefits associated with polyhydroxyalkanoates (PHA) in tissue engineering include high immunotolerance, low toxicity, and biodegradability. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx), a molecule from the PHA family of biopolymers, sh... Read More about Poly (3-Hydroxybutyrate-co-3-Hydroxyhexanoate)/Collagen Hybrid Scaffolds for Tissue Engineering Applications.

The Oswestry Risk Index: An aid in the treatment of metastatic disease of the spine (2013)
Journal Article
Balain, B., Jaiswal, A., Trivedi, J. M., Eisenstein, S. M., Kuiper, J. H., & Jaffray, D. C. (2013). The Oswestry Risk Index: An aid in the treatment of metastatic disease of the spine. The Bone & Joint Journal, 95-B(2), 210-216. https://doi.org/10.1302/0301-620x.95b2.29323

The revised Tokuhashi, Tomita and modified Bauer scores are commonly used to make difficult decisions in the management of patients presenting with spinal metastases. A prospective cohort study of 199 consecutive patients presenting with spinal metas... Read More about The Oswestry Risk Index: An aid in the treatment of metastatic disease of the spine.

Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms. (2013)
Journal Article
(2013). Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms. Respiratory Research, 9 - ?. https://doi.org/10.1186/1465-9921-14-9

BACKGROUND: Mesenchymal stem cells (MSC) are in clinical trials for widespread indications including musculoskeletal, neurological, cardiac and haematological disorders. Furthermore, MSC can ameliorate pulmonary fibrosis in animal models although mec... Read More about Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms..

Errata: Study of optical properties and proteoglycan content of tendons by polarization sensitive optical coherence tomography (2013)
Journal Article
Yang, Y., Rupani, A., Bagnaninchi, P., Wimpenny, I., & Weightman, A. (2013). Errata: Study of optical properties and proteoglycan content of tendons by polarization sensitive optical coherence tomography. Journal of Biomedical Optics, 18(1), 019801. https://doi.org/10.1117/1.JBO.18.1.019801

This article [J. Biomed. Opt.. 17, (8 ), 081417 (2012)] was originally published online on 2 August 2012 with an error in the reference citation of Fig. 1. The correct figure caption and references for Fig. 1 are shown below. A new reference was adde... Read More about Errata: Study of optical properties and proteoglycan content of tendons by polarization sensitive optical coherence tomography.

Antimalarial pharmacology and therapeutics of atovaquone (2013)
Journal Article
(2013). Antimalarial pharmacology and therapeutics of atovaquone. Journal of Antimicrobial Chemotherapy, 977-985. https://doi.org/10.1093/jac/dks504

Atovaquone is used as a fixed-dose combination with proguanil (Malarone) for treating children and adults with uncomplicated malaria or as chemoprophylaxis for preventing malaria in travellers. Indeed, in the USA, between 2009 and 2011, Malarone pres... Read More about Antimalarial pharmacology and therapeutics of atovaquone.

Effects of dietary nutrients on volatile breath metabolites (2013)
Journal Article
(2013). Effects of dietary nutrients on volatile breath metabolites. Journal of Nutritional Science, e34 - ?. https://doi.org/10.1017/jns.2013.26

Breath analysis is becoming increasingly established as a means of assessing metabolic, biochemical and physiological function in health and disease. The methods available for these analyses exploit a variety of complex physicochemical principles, bu... Read More about Effects of dietary nutrients on volatile breath metabolites.

A new precursor for conducting polymer-based brush interfaces with electroactivity in aqueous solution (2012)
Journal Article
Strover, L. T., Malmström, J., Laita, O., Reynisson, J., Aydemir, N., Nieuwoudt, M. K., …Travas-Sejdic, J. (2013). A new precursor for conducting polymer-based brush interfaces with electroactivity in aqueous solution. Polymer, 54(4), 1305-1317. https://doi.org/10.1016/j.polymer.2012.11.083

We present the synthesis of a novel conducting polymer (CP) incorporating both pyrrole and thiophene units in its monomer, which is also substituted with an initiator for grafting of sidechains by atom-transfer radical polymerisation (ATRP). The prec... Read More about A new precursor for conducting polymer-based brush interfaces with electroactivity in aqueous solution.

Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity (2012)
Journal Article
McCoull, W., Barton, P., Broo, A., Brown, A. J. H., Clarke, D. S., Coope, G., …Williams, E. J. (2013). Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity. MedChemComm, 4(2), 456. https://doi.org/10.1039/c2md20340e

A pyrazolo-pyrimidinone based series of growth hormone secretagogue receptor type 1a (GHS-R1a) antagonists and inverse agonists were identified using a scaffold hop from known quinazolinone GHS-R1a modulators. Lipophilicity was reduced to decrease hE... Read More about Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity.

Delivery of short interfering ribonucleic acid-complexed magnetic nanoparticles in an oscillating field occurs via caveolae-mediated endocytosis (2012)
Journal Article
(2012). Delivery of short interfering ribonucleic acid-complexed magnetic nanoparticles in an oscillating field occurs via caveolae-mediated endocytosis. PloS one, e51350 -?. https://doi.org/10.1371/journal.pone.0051350

Gene delivery technologies to introduce foreign genes into highly differentiated mammalian cells have improved significantly over the last few decades. Relatively new techniques such as magnetic nanoparticle-based gene transfection technology are sho... Read More about Delivery of short interfering ribonucleic acid-complexed magnetic nanoparticles in an oscillating field occurs via caveolae-mediated endocytosis.

Oxidative rearrangement of tertiary propargylic alcohols (2012)
Journal Article
Rodríguez, A., & Moran, W. J. (2013). Oxidative rearrangement of tertiary propargylic alcohols. SYNLETT, 24(1), 102-104. https://doi.org/10.1055/s-0032-1317711

An oxidative rearrangement of tertiary alcohols mediated by m-CPBA is described that generates tetrasubstituted alkenes with a carboxylic acid substituent. The mechanism of the reaction is proposed to proceed through epoxidation of the alkyne to form... Read More about Oxidative rearrangement of tertiary propargylic alcohols.

Arcuate Nucleus Homeostatic Systems are Not Altered Immediately Prior to the Scheduled Consumption of Large, Binge-Type Meals of Palatable Solid or Liquid Diet in Rats and Mice (2012)
Journal Article
Bake, T., Duncan, J. S., Morgan, D. G. A., & Mercer, J. G. (2013). Arcuate Nucleus Homeostatic Systems are Not Altered Immediately Prior to the Scheduled Consumption of Large, Binge-Type Meals of Palatable Solid or Liquid Diet in Rats and Mice. Journal of Neuroendocrinology, 25(4), 357-371. https://doi.org/10.1111/jne.12008

Meal feeding is a critical issue in the over-consumption of calories leading to human obesity. To investigate the mechanisms involved in the regulation of meal feeding in rodents, we studied a scheduled feeding regime that induces substantial food in... Read More about Arcuate Nucleus Homeostatic Systems are Not Altered Immediately Prior to the Scheduled Consumption of Large, Binge-Type Meals of Palatable Solid or Liquid Diet in Rats and Mice.

Developing consensus-based policy solutions for medicines adherence for Europe: a Delphi study (2012)
Journal Article
White. (2012). Developing consensus-based policy solutions for medicines adherence for Europe: a Delphi study. BMC Health Services Research, 425 -?. https://doi.org/10.1186/1472-6963-12-425

BACKGROUND: Non-adherence to prescribed medication is a pervasive problem that can incur serious effects on patients' health outcomes and well-being, and the availability of resources in healthcare systems. This study aimed to develop practical conse... Read More about Developing consensus-based policy solutions for medicines adherence for Europe: a Delphi study.

DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems (2012)
Journal Article
Hume, P. A., Brimble, M. A., & Reynisson, J. (2013). DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems. Computational and Theoretical Chemistry, 1005, 9-15. https://doi.org/10.1016/j.comptc.2012.10.022

Mitomycin C is a DNA alkylating agent activated by bioreduction. It has been in clinical use against a range of solid tumours since the 1960s. Its DNA adduct formation mechanism has been extensively studied and it therefore presents an excellent test... Read More about DNA adduct formation of mitomycin C. A test case for DFT calculations on model systems.

Atrial fibrillation in heart failure: an innocent bystander? (2012)
Journal Article
Mamas. (2012). Atrial fibrillation in heart failure: an innocent bystander?. Current Cardiology Reviews, 273 - 280. https://doi.org/10.2174/157340312803760839

Heart failure (HF) and atrial fibrillation (AF) frequently coexist and each complicates the course of the other. The purpose of this review is to analyse the prognostic impact of AF in patients with HF and assess whether there is an advantage in targ... Read More about Atrial fibrillation in heart failure: an innocent bystander?.

Student perceptions of the progress test in two settings and the implications for test deployment (2012)
Journal Article
(2012). Student perceptions of the progress test in two settings and the implications for test deployment. Advances in Health Sciences Education, 573-583. https://doi.org/10.1007/s10459-011-9334-z

Background The Progress Test (PT) was developed to assess student learning within integrated curricula. Whilst it is effective in promoting and rewarding deep approaches to learning in some settings, we hypothesised that implementation of the curricu... Read More about Student perceptions of the progress test in two settings and the implications for test deployment.

Microbial Reduction of Arsenic-Doped Schwertmannite by Geobacter sulfurreducens (2012)
Journal Article
Cutting, R. S., Coker, V. S., Telling, N. D., Kimber, R. L., van der Laan, G., Pattrick, R. A. D., …Lloyd, J. R. (2012). Microbial Reduction of Arsenic-Doped Schwertmannite by Geobacter sulfurreducens. Environmental Science and Technology, 46(22), 12591-12599. https://doi.org/10.1021/es204596z

The fate of As(V) during microbial reduction by Geobacter sulfurreducens of Fe(III) in synthetic arsenic-bearing schwertmannites has been investigated. During incubation at pH7, the rate of biological Fe(III) reduction increased with increasing initi... Read More about Microbial Reduction of Arsenic-Doped Schwertmannite by Geobacter sulfurreducens.

Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model (2012)
Journal Article
Rutter, A. V., Chippendale, T. W. E., Yang, Y., Španěl, P., Smith, D., & Sulé-Suso, J. (in press). Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model. Analyst, 138(1), 91-95. https://doi.org/10.1039/c2an36185j

Our previous studies have shown that both lung cancer cells and non-malignant lung cells release acetaldehyde in vitro. However, data from other laboratories have produced conflicting results. Furthermore, all these studies have been carried out in 2... Read More about Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model.