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All Outputs (13)

MANTA - A randomized phase II study of fulvestrant in combination with the dual mTOR inhibitor AZD2014 or everolimus or fulvestrant alone in estrogen receptor-positive advanced or metastatic breast cancer (2017)
Presentation / Conference
Schmid, P., Zaiss, M., Harper-Wynne, C., Ferreira, M., Dubey, S., Chan, S., …Cortes Castan, J. (2017, December). MANTA - A randomized phase II study of fulvestrant in combination with the dual mTOR inhibitor AZD2014 or everolimus or fulvestrant alone in estrogen receptor-positive advanced or metastatic breast cancer. Paper presented at 2017 San Antonio Breast Cancer Symposium, San Antonio, Texas

Background: Resistance to endocrine therapy remains a major clinical challenge with aberrant PI3K/ mTOR pathway activation being one of the main drivers. Randomised clinical trials have demonstrated a substantial benefit of adding everolimus to endoc... Read More about MANTA - A randomized phase II study of fulvestrant in combination with the dual mTOR inhibitor AZD2014 or everolimus or fulvestrant alone in estrogen receptor-positive advanced or metastatic breast cancer.

Evaluation of a pharmacist-led telephone triage service in a GP Practice (2017)
Presentation / Conference
Kit Yan, C., White, S., Patel, B., & Chapman, S. (2017, December). Evaluation of a pharmacist-led telephone triage service in a GP Practice. Poster presented at Royal Pharmaceutical Society (RPS) Winter Summit 2017, London, UK

Poster abstract from Conference; Royal Pharmaceutical Society Winter Summit 2017.

Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines (2017)
Presentation / Conference
Rosa Johnson-Ajinwo, O., Richardson, A., & Li, W. (2017, September). Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines. Presented at IUPHAR, Aberdeen

Ovarian cancer is the second leading cause of death among women in the gynaecological category of cancers. The current post surgery treatment which involves the use of platinum-based therapy with its attendant adverse drug-resistance often results in... Read More about Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines.

Coumarin antifungal lead compounds, predicted mechanism of action (2017)
Presentation / Conference
Kingsford-Adaboh, R., Moscoh, D., & Reynisson, J. (2017, August). Coumarin antifungal lead compounds, predicted mechanism of action. Poster presented at XXIV IUCr Congress, Hyderabad International Convention Centre, Hyderabad, India

Introduction: Candida albicans is one of the most common causative fungi infection despite major efforts to control it. C. albicans has emerged as one of the main causes of morbidity and mortality in immunocompromised patients suffering from, e.g., c... Read More about Coumarin antifungal lead compounds, predicted mechanism of action.

Facilitating the operational readiness of the NHS for the in-house manufacture and delivery of autologous cell therapy (2017)
Presentation / Conference
Ziya, S., Medcalf, N., El, A., & Wright, K. (2017, June). Facilitating the operational readiness of the NHS for the in-house manufacture and delivery of autologous cell therapy. Poster presented at ISCT 2017 Annual Meeting, London, UK

Introduction: Cell-based therapies (CBTs) have been shown to confer regenerative capacity in various pathologies. The production of such treatments require a range of business models. These business models either align with or disrupt the current c... Read More about Facilitating the operational readiness of the NHS for the in-house manufacture and delivery of autologous cell therapy.

ADVANCES IN X-RAY MICROSCOPY FOR THE ANALYSIS OF TRANSITION METALS IN THE BRAIN (2017)
Presentation / Conference
Collingwood, J., Everett, J., Telling, N., & Adams, F. (2017, May). ADVANCES IN X-RAY MICROSCOPY FOR THE ANALYSIS OF TRANSITION METALS IN THE BRAIN. Poster presented at Seventh Congress of the International BioIron Society (IBIS) Biennial World Meeting (BioIron 2017)

Introduction: X-rays have the advantage that they have a short wavelength and can penetrate through a thick biological sample. It was the need to ‘see inside’ opaque objects, especially biological tissues, and to resolve features too small for optica... Read More about ADVANCES IN X-RAY MICROSCOPY FOR THE ANALYSIS OF TRANSITION METALS IN THE BRAIN.

Partial breast radiotherapy after breast conservation: 5 year outcomes from the IMPORT LOW (CRUK/06/003) phase III trial (2017)
Presentation / Conference
Coles, C., Griffin, C., Kirby, A., Agrawal, R., Alhasso, A., Bhattacharya, I., …Bliss, J. (2017, May). Partial breast radiotherapy after breast conservation: 5 year outcomes from the IMPORT LOW (CRUK/06/003) phase III trial. Paper presented at ESTRO 36, Vienna, Austria

Conference abstract. Part of special issue: ESTRO 36, May 5-9, 2017, Vienna, Austria.

Pharmacy staff perspectives on the role of community pharmacy in the provision of first aid and responding to emergencies: a qualitative study. (2017)
Presentation / Conference
Liaskou, M., White, S., Moss, G., Ratcliffe, N., & Cook, J. (2017, April). Pharmacy staff perspectives on the role of community pharmacy in the provision of first aid and responding to emergencies: a qualitative study. Presented at Health Services Research and Pharmacy Practice Conference, University of Nottingham, UK

No abstract

Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity (2017)
Presentation / Conference
Mennan, C., Owen, S., Garcia, J., McCarthy, H., Banerjee, R., Roberts, S., & Richardson, J. (2017, March). Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity. Poster presented at British Society for Matrix Biology “The Grey Area – Age and the Extracellular Matrix”

Introduction The maintenance of chondrogenic phenotype in human articular chondrocytes grown in continuous normoxic (21% O2) and hypoxic (2% O2) conditions was assessed, with the aim of finding the best environment for culturing cells destined for ca... Read More about Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity.

Frequency of testing for glycated haemoglobin, HbA1c, affects likelihood of reaching target levels in patients with diabetes independently of starting value (2017)
Presentation / Conference
Driskell, O., Duff, C., Holland, D., Waldron, J., Ford, C., Tran, M., …Heald, A. (2017, March). Frequency of testing for glycated haemoglobin, HbA1c, affects likelihood of reaching target levels in patients with diabetes independently of starting value. Poster presented at Diabetes UK Professional Conference 2017, Manchester, UK

Objectives: Studies have established that there is a clear link between monitoring frequency and diabetes control. Nevertheless, the wider question of optimum number of tests per year to attain target HbA1c remains unclear. Methods: Data on all Hb... Read More about Frequency of testing for glycated haemoglobin, HbA1c, affects likelihood of reaching target levels in patients with diabetes independently of starting value.