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The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumours and other abnormal brain masses. (2010)
Journal Article
(2010). The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumours and other abnormal brain masses. BMC Bioinformatics, 581 -581. https://doi.org/10.1186/1471-2105-11-581

Background Proton Magnetic Resonance (MR) Spectroscopy (MRS) is a widely available technique for those clinical centres equipped with MR scanners. Unlike the rest of MR-based techniques, MRS yields not images but spectra of metabolites in the tissue... Read More about The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumours and other abnormal brain masses..

Programmable patients: simulation of consultation skills in a virtual environment (2010)
Journal Article
(2010). Programmable patients: simulation of consultation skills in a virtual environment. Bio-Algorithms and Medical-Systems, 111 -115

The School of Pharmacy has developed 3D characters in a virtual environment to simulate interaction between the learner and a virtual patient. Interaction with the patient is possible through the use of multiple choice questions or ‘natural’ free tex... Read More about Programmable patients: simulation of consultation skills in a virtual environment.

No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients (2010)
Journal Article
Kuiper. (2010). No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients. Acta Orthopaedica Belgica, 619 - 627

We performed a prospective, randomised controlled trial to assess the differences in the use of a conventional suction drain, an Autologous Blood Transfusion (ABT) drain and no drain, in 168 patients. There was no significant difference between the d... Read More about No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients.

Compositional and structural medium energy ion scattering study of the temperature mediated diffusion determination at the Co/V interface in Co/V/MgO(100) (2010)
Journal Article
Díaz, M., Martínez, L., Román, E., Redondo-Cubero, A., Muñoz-Márquez, M., van der Laan, G., …Huttel, Y. (2010). Compositional and structural medium energy ion scattering study of the temperature mediated diffusion determination at the Co/V interface in Co/V/MgO(100). Surface Science, 604(23-24), 2177-2183. https://doi.org/10.1016/j.susc.2010.09.011

The impact of annealing at 300 °C on the elemental composition and the atomic structure of the Co/V interface in the 2.5 Å Co/70 Å V/MgO (100) system has been investigated by medium energy ion scattering (MEIS) using 100 keV He+ ions. By combining th... Read More about Compositional and structural medium energy ion scattering study of the temperature mediated diffusion determination at the Co/V interface in Co/V/MgO(100).

The peritoneal osmotic conductance is low well before the diagnosis of encapsulating peritoneal sclerosis is made (2010)
Journal Article
(2010). The peritoneal osmotic conductance is low well before the diagnosis of encapsulating peritoneal sclerosis is made. Kidney International, 611 - 618. https://doi.org/10.1038/ki.2010.186

Encapsulating peritoneal sclerosis (EPS) is a serious condition whose frequency is increasing the longer the duration of peritoneal dialysis. To identify prognostic indicators of EPS, we studied here longitudinal changes in peritoneal membrane functi... Read More about The peritoneal osmotic conductance is low well before the diagnosis of encapsulating peritoneal sclerosis is made.

Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis (2010)
Journal Article
(2010). Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis. Thorax, 884 - 890. https://doi.org/10.1136/thx.2009.134072

Background Several scoring systems have been used to predict mortality in patients with community-acquired pneumonia. The properties of commonly used risk stratification scales were systematically reviewed. Methods MEDLINE and EMBASE (January 1999... Read More about Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis.

Annual consultation prevalence of regional musculoskeletal problems in primary care: an observational study. (2010)
Journal Article
Jordan. (2010). Annual consultation prevalence of regional musculoskeletal problems in primary care: an observational study. BMC Musculoskeletal Disorders, 144 -?. https://doi.org/10.1186/1471-2474-11-144

BACKGROUND: Regional musculoskeletal pain such as back or shoulder pain are commonly reported symptoms in the community. The extent of consultation to primary care with such problems is unknown as a variety of labels may be used to record such consul... Read More about Annual consultation prevalence of regional musculoskeletal problems in primary care: an observational study..

Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity. (2010)
Journal Article
(2010). Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity. Biochemical and Biophysical Research Communications, 79 - 85. https://doi.org/10.1016/j.bbrc.2010.06.039

The nucleoside diphosphate (NDP) kinase, Nm23H1, is a highly expressed during neuronal development, whilst induced over-expression in neuronal cells results in increased neurite outgrowth. Extracellular Nm23H1 affects the survival, proliferation and... Read More about Extracellular Nm23H1 stimulates neurite outgrowth from dorsal root ganglia neurons in vitro independently of nerve growth factor supplementation or its nucleoside diphosphate kinase activity..

A comparison of high-content screening versus manual analysis to assay the effects of mesenchymal stem cell-conditioned medium on neurite outgrowth in vitro. (2010)
Journal Article
(2010). A comparison of high-content screening versus manual analysis to assay the effects of mesenchymal stem cell-conditioned medium on neurite outgrowth in vitro. Journal of Biomolecular Screening, 576 - 582. https://doi.org/10.1177/1087057110367959

Bone marrow mesenchymal stem cells (MSCs) promote nerve growth and functional recovery in animal models of spinal cord injury (SCI) to varying levels. The authors have tested high-content screening to examine the effects of MSC-conditioned medium (MS... Read More about A comparison of high-content screening versus manual analysis to assay the effects of mesenchymal stem cell-conditioned medium on neurite outgrowth in vitro..

Critical overview of the benefits and harms of aspirin (2010)
Journal Article
(2010). Critical overview of the benefits and harms of aspirin. Pharmaceuticals, 1491 - 1506. https://doi.org/10.3390/ph3051491

Aspirin is widely used internationally for a variety of indications, with the most prominent one being that of cardiovascular disease. However, aspirin has also been proposed as a treatment option in a diverse range of conditions such as diabetes mel... Read More about Critical overview of the benefits and harms of aspirin.

Microbial Engineering of Nanoheterostructures: Biological Synthesis of a Magnetically Recoverable Palladium Nanocatalyst (2010)
Journal Article
Coker, V. S., Bennett, J. A., Telling, N. D., Henkel, T., Charnock, J. M., van der Laan, G., …Lloyd, J. R. (2010). Microbial Engineering of Nanoheterostructures: Biological Synthesis of a Magnetically Recoverable Palladium Nanocatalyst. ACS Nano, 4(5), 2577-2584. https://doi.org/10.1021/nn9017944

Precious metals supported on ferrimagnetic particles have a diverse range of uses in catalysis. However, fabrication using synthetic methods results in potentially high environmental and economic costs. Here we show a novel biotechnological route for... Read More about Microbial Engineering of Nanoheterostructures: Biological Synthesis of a Magnetically Recoverable Palladium Nanocatalyst.

Fe site occupancy in magnetite-ulvospinel solid solutions: A new approach using X-ray magnetic circular dichroism (2010)
Journal Article
Pearce, C. I., Henderson, C. M. B., Telling, N. D., Pattrick, R. A., Charnock, J. M., Coker, V. S., …van der Laan, G. (2010). Fe site occupancy in magnetite-ulvospinel solid solutions: A new approach using X-ray magnetic circular dichroism. American Mineralogist, 95(4), 425-439. https://doi.org/10.2138/am.2010.3343

Ordering of Fe3+ and Fe2+ cations between octahedral and tetrahedral sites in synthetic members of the magnetite-ulvöspinel (Fe3O4-Fe2TiO4) solid-solution series was determined using Fe L2,3-edge X-ray magnetic circular dichroism (XMCD) coupled with... Read More about Fe site occupancy in magnetite-ulvospinel solid solutions: A new approach using X-ray magnetic circular dichroism.

Optimizing Cr(VI) and Tc(VII) Remediation through Nanoscale Biomineral Engineering (2010)
Journal Article
Cutting, R. S., Coker, V. S., Telling, N. D., Kimber, R. L., Pearce, C. I., Ellis, B. L., …Lloyd, J. R. (2010). Optimizing Cr(VI) and Tc(VII) Remediation through Nanoscale Biomineral Engineering. Environmental Science and Technology, 44(7), 2577-2584. https://doi.org/10.1021/es902119u

The influence of Fe(III) starting material on the ability of magnetically recoverable biogenic magnetites produced by Geobacter sulfurreducens to retain metal oxyanion contaminants has been investigated. The reduction/removal of aqueous Cr(VI) was us... Read More about Optimizing Cr(VI) and Tc(VII) Remediation through Nanoscale Biomineral Engineering.

SpectraClassifier 1.0: a user friendly, automated MRS-based classifier-development system (2010)
Journal Article
(2010). SpectraClassifier 1.0: a user friendly, automated MRS-based classifier-development system. BMC Bioinformatics, 106 - 106. https://doi.org/10.1186/1471-2105-11-106

Background SpectraClassifier (SC) is a Java solution for designing and implementing Magnetic Resonance Spectroscopy (MRS)-based classifiers. The main goal of SC is to allow users with minimum background knowledge of multivariate statistics to perfor... Read More about SpectraClassifier 1.0: a user friendly, automated MRS-based classifier-development system.

Spectromicroscopy study of interfacial Co/NiO(001) (2010)
Journal Article
van der Laan, G., Telling, N. D., Potenza, A., Dhesi, S., & Arenholz, E. (2010). Spectromicroscopy study of interfacial Co/NiO(001). Physical Review B,

Photoemission electron microscopy (PEEM) with linearly polarized x-rays is used to determine the orientation of antiferromagnetic domains by monitoring the relative peak intensities at the 3d transition metal Lâ absorption edge. In such an analysis t... Read More about Spectromicroscopy study of interfacial Co/NiO(001).

Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression (2010)
Journal Article
Wu. (2010). Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression. Cell Research, 434 -444. https://doi.org/10.1038/cr.2010.11

We investigated the ability of fetal mesenchymal stem cells (fMSCs) to differentiate into brown and white adipocytes and compared the expression of a number of marker genes and key regulatory factors. We showed that the expression of key adipocyte re... Read More about Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression.

Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations (2010)
Journal Article
(2010). Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations. International Journal of Molecular Sciences, 967 - 981. https://doi.org/10.3390/ijms11030967

Magnetic nanoparticles (MNPs) are important contrast agents used to monitor a range of neuropathological processes; microglial cells significantly contribute to MNP uptake in sites of pathology. Microglial activation occurs following most CNS patholo... Read More about Robust uptake of magnetic nanoparticles (MNPs) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations.