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Clinical risk scores for predicting stroke-associated pneumonia: A systematic review (2016)
Journal Article
Roffe. (2016). Clinical risk scores for predicting stroke-associated pneumonia: A systematic review. European Stroke Journal, 76 - 84. https://doi.org/10.1177/2396987316651759

Purpose Several risk stratification scores for predicting stroke-associated pneumonia have been derived. We aimed to evaluate the performance and clinical usefulness of such scores for predicting stroke-associated pneumonia. Method A systematic... Read More about Clinical risk scores for predicting stroke-associated pneumonia: A systematic review.

Computational study of core-shell droplet formation in coaxial electrohydrodynamic atomization process (2016)
Journal Article
Yan, W., Davoodi, P., Tong, Y. W., & Wang, C. (2016). Computational study of core-shell droplet formation in coaxial electrohydrodynamic atomization process. AIChE journal, 62(12), 4259-4276. https://doi.org/10.1002/aic.15361

In this study, a computational fluid dynamic (CFD) model was developed to simulate the liquid cone-jet and core-shell droplet formation in the Coaxial Electrohydrodynamic Atomization (CEHDA) process. Validation experiments were conducted using poly(l... Read More about Computational study of core-shell droplet formation in coaxial electrohydrodynamic atomization process.

Part II: Functional Delivery of a Neurotherapeutic Gene to Neural Stem Cells using Minicircle DNA and Nanoparticles: Translational advantages for Regenerative Neurology (2016)
Journal Article
Fernandes, A. R., & Chari, D. M. (2016). Part II: Functional Delivery of a Neurotherapeutic Gene to Neural Stem Cells using Minicircle DNA and Nanoparticles: Translational advantages for Regenerative Neurology. Journal of Controlled Release, 300-310. https://doi.org/10.1016/j.jconrel.2016.06.039

Both neurotrophin-based therapy and neural stem cell (NSC)-based strategies have progressed to clinical trials for treatment of neurological diseases and injuries. Brain-derived neurotrophic factor (BDNF) in particular can confer neuroprotective and... Read More about Part II: Functional Delivery of a Neurotherapeutic Gene to Neural Stem Cells using Minicircle DNA and Nanoparticles: Translational advantages for Regenerative Neurology.

Specific localization of nesprin-1-a2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody. (2016)
Journal Article
(2016). Specific localization of nesprin-1-a2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody. https://doi.org/10.1186/s12860-016-0105-9

BACKGROUND: Nesprin-1-giant (1008kD) is a protein of the outer nuclear membrane that links nuclei to the actin cytoskeleton via amino-terminal calponin homology domains. The short nesprin-1 isoform, nesprin-1-a2, is present only in skeletal and cardi... Read More about Specific localization of nesprin-1-a2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody..

A comparative study of skin cell activities in collagen and fibrin constructs. (2016)
Journal Article
Yang, Y. (2016). A comparative study of skin cell activities in collagen and fibrin constructs. Medical Engineering and Physics, 854 -861. https://doi.org/10.1016/j.medengphy.2016.05.017

Collagen and fibrin are widely used in tissue engineering due to their excellent biocompatibility and bioactivities that support in vivo tissue formation. These two hydrogels naturally present in different wound healing stages with different regulato... Read More about A comparative study of skin cell activities in collagen and fibrin constructs..

A systematic review – ovarian suppression with GnRH analogues for management of PMS (2016)
Journal Article
Naheed, B., Kuiper, J., & O'Brien, S. (2016). A systematic review – ovarian suppression with GnRH analogues for management of PMS. BJOG: An International Journal of Obstetrics and Gynaecology, 123, 186. https://doi.org/10.1111/1471-0528.14109

Introduction Premenstrual syndrome (PMS) is a psychological and somatic disorder.It occurs in about 5–8% of women .PMS symptoms recur during the luteal phase of the menstrual cycle and remit by the end of menstruation. Premenstrual Disorders have a d... Read More about A systematic review – ovarian suppression with GnRH analogues for management of PMS.

Monoclonal antibody Py recognizes neurofilament heavy chain and is a selective marker for large diameter neurons in the brain Brain Structure and Function (2016)
Journal Article
Fuller, H. R., Marani, L., Holt, I., Woodhams, P. L., Webb, M. M., & Gates, M. A. (2016). Monoclonal antibody Py recognizes neurofilament heavy chain and is a selective marker for large diameter neurons in the brain Brain Structure and Function. Brain Structure and Function, 807-879. https://doi.org/10.1007/s00429-016-1252-7

Almost 30 years ago, the monoclonal antibody Py was developed to detect pyramidal neurons in the CA3 region of the rat hippocampus. The utility of this antibody quickly expanded when several groups discovered that it could be used to identify very sp... Read More about Monoclonal antibody Py recognizes neurofilament heavy chain and is a selective marker for large diameter neurons in the brain Brain Structure and Function.

Synthesis and Characterisation of TPGS-Gemcitabine Prodrug Micelles for Pancreatic Cancer therapy (2016)
Journal Article
(2016). Synthesis and Characterisation of TPGS-Gemcitabine Prodrug Micelles for Pancreatic Cancer therapy. RSC advances, 60126-60137. https://doi.org/10.1039/C6RA09347G

The therapeutic potential of a nucleoside analog, gemcitabine, is severely compromised due to its rapid clearance from systemic circulation by enzymatic degradation into an inactive metabolite. In the present investigation, micelles based on polymer–... Read More about Synthesis and Characterisation of TPGS-Gemcitabine Prodrug Micelles for Pancreatic Cancer therapy.

Comparison of different light sources for trapping Culicoides biting midges, mosquitoes and other dipterans (2016)
Journal Article
(2016). Comparison of different light sources for trapping Culicoides biting midges, mosquitoes and other dipterans. Veterinary Parasitology, 44-49. https://doi.org/10.1016/j.vetpar.2016.06.020

The response of Culicoides biting midges, mosquitoes and other dipterans to different wavelengths was evaluated in a farm meadow in northern Spain. A total of 9449 specimens of 23 species of Culicoides, 5495 other ceratopogonids (non-biting midges),... Read More about Comparison of different light sources for trapping Culicoides biting midges, mosquitoes and other dipterans.

Part I: Minicircle vector technology limits DNA size restrictions on ex vivo gene delivery using nanoparticle vectors: Overcoming a translational barrier in neural stem cell therapy (2016)
Journal Article
Chari, & Fernandes, A. R. (2016). Part I: Minicircle vector technology limits DNA size restrictions on ex vivo gene delivery using nanoparticle vectors: Overcoming a translational barrier in neural stem cell therapy. Journal of Controlled Release, 289-299. https://doi.org/10.1016/j.jconrel.2016.06.024

Genetically engineered neural stem cell (NSC) transplant populations offer key benefits in regenerative neurology, for release of therapeutic biomolecules in ex vivo gene therapy. NSCs are ‘hard-to-transfect’ but amenable to ‘magnetofection’. Despite... Read More about Part I: Minicircle vector technology limits DNA size restrictions on ex vivo gene delivery using nanoparticle vectors: Overcoming a translational barrier in neural stem cell therapy.

Advances of Plant-Derived Natural Products in Ovarian Cancer Therapy (2016)
Journal Article
Li, W., Rosa Johnson-Ajinwo, O., & Ijeoma Uche, F. (2016). Advances of Plant-Derived Natural Products in Ovarian Cancer Therapy. International Journal of Cancer Research and Prevention, 81 - 105

Ovarian cancer is the leading cause of death in the gynaecologic cancers within the UK and US. Presently the standard treatment for ovarian cancer entails the use of chemotherapy drugs paclitaxel and carboplatin after aggressive surgical reduction in... Read More about Advances of Plant-Derived Natural Products in Ovarian Cancer Therapy.

Cytotoxicity Effects and Apoptosis Induction by Bisbenzylisoquinoline Alkaloids from Triclisia subcordata (2016)
Journal Article
Uche, F., Drijfhout, F., McCullagh, J., Richardson, A., & Li, W. (2016). Cytotoxicity Effects and Apoptosis Induction by Bisbenzylisoquinoline Alkaloids from Triclisia subcordata. Phytotherapy Research, 1533-1539. https://doi.org/10.1002/ptr.5660

Triclisia subcordata Oliv (Menispermeaceae) is a medicinal plant traditionally used for the treatment of various diseases in West Africa. The ethanol extract of T.?subcordata and its fractions were screened for in vitro anti-ovarian cancer activities... Read More about Cytotoxicity Effects and Apoptosis Induction by Bisbenzylisoquinoline Alkaloids from Triclisia subcordata.

Cytotoxicity effects and apoptosis induction by cycleanine and tetrandrine (2016)
Journal Article
Li, W., & Richardson, A. (2016). Cytotoxicity effects and apoptosis induction by cycleanine and tetrandrine. Phytotherapy Research, 1533-1539. https://doi.org/10.1002/ptr.5660

Triclisia subcordata Oliv (Menispermeaceae) is a medicinal plant traditionally used for the treatment of various diseases in West Africa. The ethanol extract of T.?subcordata and its fractions were screened for in vitro anti-ovarian cancer activities... Read More about Cytotoxicity effects and apoptosis induction by cycleanine and tetrandrine.