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All Outputs (243)

Did Cost Inhibit the Uptake of More potent Statins? (2016)
Journal Article
(2016). Did Cost Inhibit the Uptake of More potent Statins?. Pharmacoepidemiology and Drug Safety, 984-991. https://doi.org/10.1002/pds.4231

Background The use of statins has increased substantially over the last 2 decades in England and represents a significant cost burden to the National Health Service. Therefore, it is important to understand what influences prescribers' choice. Ob... Read More about Did Cost Inhibit the Uptake of More potent Statins?.

Accelerating and increasing nano-scaled pore formation on electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) fibers. (2016)
Journal Article
Yang, Y. (2016). Accelerating and increasing nano-scaled pore formation on electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) fibers. Journal of Biomaterials Science, Polymer Edition, 1155 - 1169. https://doi.org/10.1080/09205063.2016.1184122

Porous fibers are advantageous for filtration systems, drug delivery systems, and in the field of tissue engineering, in comparison to their non-porous counterparts. In this study, we developed a facile technique including two steps to generate poly(... Read More about Accelerating and increasing nano-scaled pore formation on electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) fibers..

Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke (2016)
Journal Article
Roffe. (2016). Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. New England Journal of Medicine, 2313-2323. https://doi.org/10.1056/NEJMoa1515510

BACKGROUND Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose of intravenous alteplase may improve recovery along with a reduced risk of intracerebral hemorrhage. METHODS Using a 2-by-2 quasi-factorial open-label desi... Read More about Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke.

Determinants and outcomes of stroke following percutaneous coronary intervention by indication (2016)
Journal Article
Roffe, & Mamas. (2016). Determinants and outcomes of stroke following percutaneous coronary intervention by indication. Stroke, 1500-1507. https://doi.org/10.1161/strokeaha.116.012700

Background and Purpose—Stroke after percutaneous coronary intervention (PCI) is a serious complication, but its determinants and outcomes after PCI in different clinical settings are poorly documented. Methods—The British Cardiovascular Interventi... Read More about Determinants and outcomes of stroke following percutaneous coronary intervention by indication.

Assessing chronic cough in children (2016)
Journal Article
Gilchrist. (2016). Assessing chronic cough in children. Paediatrics and Child Health, 273-275. https://doi.org/10.1016/j.paed.2016.03.002

Cough is a protective physiological reflex that aids the clearance of airway secretions and aspirated material. As such, it is normal to cough. Coughing becomes abnormal when the frequency or severity impacts on the child's ability to eat, sleep, pla... Read More about Assessing chronic cough in children.

Correction: Optofluidic lens with low spherical and low field curvature aberrations (2016)
Journal Article
Zhao, H. T., Yang, Y., Chin, L. K., Chen, H. F., Zhu, W. M., Zhang, J. B., …Liu, A. Q. (in press). Correction: Optofluidic lens with low spherical and low field curvature aberrations. Lab on a Chip, 16(11), 2135-2135. https://doi.org/10.1039/c6lc90052f

Correction for ‘Optofluidic lens with low spherical and low field curvature aberrations’ by H. T. Zhao et al., Lab Chip, 2016, 16, 1617–1624. Funding information given in the Acknowledgements section is incorrect.

A review of prednisolone prescribing for children with acute asthma in the UK (2016)
Journal Article
Gilchrist, F. J., Ahmad, A. N., Batchelor, H. K., Marriott, J. F., & Lenney, W. (2016). A review of prednisolone prescribing for children with acute asthma in the UK. Journal of Asthma, 53(6), 563 -566. https://doi.org/10.3109/02770903.2015.1118498

INTRODUCTION: Worldwide asthma guidelines recommend short courses of oral prednisolone in children with acute exacerbations generating high prescription numbers. There is a paucity of evidence to inform the optimal dose and course duration. This has... Read More about A review of prednisolone prescribing for children with acute asthma in the UK.

Medium- and long-term results of high tibial osteotomy using Garches external fixator and gait analysis for dynamic correction in varus osteoarthritis of the knee. (2016)
Journal Article
McClelland, D., Barlow, D., Moores, T., Wynn-Jones, C., Griffiths, D., Ogrodnik, P., & Thomas, P. (2016). Medium- and long-term results of high tibial osteotomy using Garches external fixator and gait analysis for dynamic correction in varus osteoarthritis of the knee. The Bone & Joint Journal, 98-B(5), 601 - 607. https://doi.org/10.1302/0301-620X.98B5.34875

In arthritis of the varus knee, a high tibial osteotomy (HTO) redistributes load from the diseased medial compartment to the unaffected lateral compartment. We report the outcome of 36 patients (33 men and three women) with 42 varus, arthritic knees... Read More about Medium- and long-term results of high tibial osteotomy using Garches external fixator and gait analysis for dynamic correction in varus osteoarthritis of the knee..

Synthesis of intracellular reduction-sensitive amphiphilic polyethyleneimine and poly(ε-caprolactone) graft copolymer for on-demand release of doxorubicin and p53 plasmid DNA (2016)
Journal Article
Davoodi, P., Srinivasan, M. P., & Wang, C. (2016). Synthesis of intracellular reduction-sensitive amphiphilic polyethyleneimine and poly(ε-caprolactone) graft copolymer for on-demand release of doxorubicin and p53 plasmid DNA. Acta biomaterialia, 39, 79-93. https://doi.org/10.1016/j.actbio.2016.05.003

A contemporary risk model for predicting 30-day mortality following percutaneous coronary intervention in England and Wales (2016)
Journal Article
Mamas. (2016). A contemporary risk model for predicting 30-day mortality following percutaneous coronary intervention in England and Wales. International Journal of Cardiology, 125-132. https://doi.org/10.1016/j.ijcard.2016.02.085

Aims: The current risk model for percutaneous coronary intervention (PCI) in the UK is based on outcomes of patients who were treated in a different era of interventional cardiology. This study aimed to create a new model, based on a contemporary coh... Read More about A contemporary risk model for predicting 30-day mortality following percutaneous coronary intervention in England and Wales.

Is there a relationship of operator and center volume with access site related outcomes?: an analysis from the British Cardiovascular Intervention Society (2016)
Journal Article
Nolan, & Mamas. (2016). Is there a relationship of operator and center volume with access site related outcomes?: an analysis from the British Cardiovascular Intervention Society. Circulation: Cardiovascular Interventions, https://doi.org/10.1161/circinterventions.115.003333

Background: Transradial access (TRA) is associated with reduced access site related bleeding complications and mortality post percutaneous coronary intervention (PCI). The objective of this study is to examine the relationship between access site pra... Read More about Is there a relationship of operator and center volume with access site related outcomes?: an analysis from the British Cardiovascular Intervention Society.

Accessing rehabilitation after stroke - a guessing game? (2016)
Journal Article
(2016). Accessing rehabilitation after stroke - a guessing game?. Disability and Rehabilitation, 709- 713. https://doi.org/10.3109/09638288.2016.1160448

AIM: To explore the use, meaning and value of the term "rehabilitation potential". METHOD: The authors of this commentary met to discuss concerns relating to the pressure on health service staff created by reduced length of stay in acute settings of... Read More about Accessing rehabilitation after stroke - a guessing game?.

Investigation into drug solubilisation potential of sulfonated calix[4]resorcinarenes (2016)
Journal Article
(2016). Investigation into drug solubilisation potential of sulfonated calix[4]resorcinarenes. Journal of Nanomedicine and Nanotechnology, https://doi.org/10.4172/2157-7439.1000370

Increasing importance is being placed on the role of drug solubilisation in the drug development pipeline. In order for drugs to successfully pass through the pre-clinical studies required before clinical trials they often require addition of excipie... Read More about Investigation into drug solubilisation potential of sulfonated calix[4]resorcinarenes.

Virtual imaging for patient information on radiotherapy planning and delivery (2016)
Presentation / Conference
Sule-Suso, J., Finney, S., Bisson, J., Hammersley, S., Jassal, S., Knight, C., …Moloney, A. (2016, April). Virtual imaging for patient information on radiotherapy planning and delivery. Poster presented at ESTRO 35, Turin, Italy

Purpose or Objective: To assess whether both patients and their relatives would welcome further information on a oneto-one basis on RT planning and delivery using the virtual reality (VR) system VERT.

Iron Oxides in the Human Brain (2016)
Book Chapter
Collingwood, J. F., & Telling, N. D. Iron Oxides in the Human Brain. In Iron Oxides: From Nature to Applications (143-176). Wiley. https://doi.org/10.1002/9783527691395.ch7

The presence and formation of iron oxide in the human brain are of interest to those engaged in understanding fundamental processes of biomineralization and of iron metabolism in neurobiology and neuropathology. There is evidence for the formation of... Read More about Iron Oxides in the Human Brain.

Flourescent, online monitoring of PLGA degradation for regenerative medicine applications (2016)
Journal Article
Yang. (2016). Flourescent, online monitoring of PLGA degradation for regenerative medicine applications. RSC advances, 44364 - 44370. https://doi.org/10.1039/C6RA04690H

Degradable polymers such as poly(lactic-co-glycolic acid) (PLGA) are frequently chosen for tissue engineering, due to their ease of production, controllable degradation rates and Food and Drug Administration (FDA) approval. Within tissue engineering... Read More about Flourescent, online monitoring of PLGA degradation for regenerative medicine applications.