Mechanical loading of bioengineered skeletal muscle in vitro recapitulates gene expression signatures of resistance exercise in vivo
(2021)
Journal Article
Turner, D. C., Gorski, P. P., Seaborne, R. A., Viggars, M., Murphy, M., Jarvis, J. C., …Sharples, A. P. (2021). Mechanical loading of bioengineered skeletal muscle in vitro recapitulates gene expression signatures of resistance exercise in vivo. Journal of Cellular Physiology, 236(9), 6534-6547. https://doi.org/10.1002/jcp.30328
Understanding the role of mechanical loading and exercise in skeletal muscle (SkM) is paramount for delineating the molecular mechanisms that govern changes in muscle mass. However, it is unknown whether loading of bioengineered SkM in vitro adequate... Read More about Mechanical loading of bioengineered skeletal muscle in vitro recapitulates gene expression signatures of resistance exercise in vivo.