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All Outputs (101)

Describing the impact of community pharmacy organisation type on emergency hormonal contraception services in England (2022)
Journal Article
Thayer, N., White, S., & Frisher, M. (2022). Describing the impact of community pharmacy organisation type on emergency hormonal contraception services in England. International Journal of Pharmacy Practice, 30(6), 514–519. https://doi.org/10.1093/ijpp/riac067

OBJECTIVES: In England, non-dispensing pharmacy services are commissioned either nationally or locally. For the national service Medicines Use Reviews (MURs), large multiple/chain pharmacies provide more consultations than independents. This study ai... Read More about Describing the impact of community pharmacy organisation type on emergency hormonal contraception services in England.

Stem cell-based therapy for human diseases. (2022)
Journal Article
Hoang, D., Pham, P., Bach, T., Ngo, A., Nguyen, Q., Phan, T., …Heke, M. (2022). Stem cell-based therapy for human diseases. Signal Transduction and Targeted Therapy, 272 - ?. https://doi.org/10.1038/s41392-022-01134-4

Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be treated. Stem cell-based therapy, including human pluripotent stem cells (hPSCs) and multipotent mesenchymal stem cells... Read More about Stem cell-based therapy for human diseases..

Allogenic Umbilical Cord Tissue for Treatment of Knee Osteoarthritis (2022)
Journal Article
Gupta, A., & Maffulli, N. (2022). Allogenic Umbilical Cord Tissue for Treatment of Knee Osteoarthritis. Sports Medicine and Arthroscopy Review, 30(3), 162-165. https://doi.org/10.1097/jsa.0000000000000350

Interest in use of perinatal allogenic tissues including clinical-grade minimally manipulated umbilical cord tissue-derived allograft formulations to treat knee osteoarthritis (OA) patients is increasing. Limited studies have characterized these form... Read More about Allogenic Umbilical Cord Tissue for Treatment of Knee Osteoarthritis.

Osteoarthritis Risks and Sports: An Evidence-based Systematic Review (2022)
Journal Article
Migliorini, F., Maffulli, N., Pintore, A., Ernst, J., Eschweiler, J., Hildebrand, F., & Betsch, M. (in press). Osteoarthritis Risks and Sports: An Evidence-based Systematic Review. Sports Medicine and Arthroscopy Review, 30(3), 118-140. https://doi.org/10.1097/jsa.0000000000000351

Purpose: Regular sports activities are associated with multiple physical and psychological health benefits. However, sports also may lead to injuries and the development of osteoarthritis (OA). This systematic review investigated the association betw... Read More about Osteoarthritis Risks and Sports: An Evidence-based Systematic Review.

Low-Dose NSAIDs Efficacy in Orthopedic Applications (2022)
Journal Article
Oliva, F., Quaranta, M., Cipollaro, L., Conti, V., De Bellis, E., Filippelli, A., & Maffulli, N. (2022). Low-Dose NSAIDs Efficacy in Orthopedic Applications. Sports Medicine and Arthroscopy Review, 30(3), 147-161. https://doi.org/10.1097/jsa.0000000000000353

Non-steroidal anti-inflammatory drugs (NSAIDs) [cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors] and COXIBs (the COX-2 selective inhibitors) may induce several potentially severe and life-threatening issues especially in elderly pati... Read More about Low-Dose NSAIDs Efficacy in Orthopedic Applications.

Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries (2022)
Journal Article
Malliaropoulos, N., Bikos, G., Tsifountoudis, I., Alaseirlis, D., Christodoulou, D., Padhiar, N., & Maffulli, N. (2023). Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries. Surgeon, 21(4), 225-229. https://doi.org/10.1016/j.surge.2022.06.002

Objective Tibial stress injuries are challenging in terms of early diagnosis, management strategy, and safe return-to-play. In the present study, pain production associated with the application of therapeutic ultrasound (TUS) was used as a primary d... Read More about Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries.

The creation of an online learning resource to support the implementation of the nice shared decision making guideline (2022)
Journal Article
Jacklin, Thompson, & Maddock. (2022). The creation of an online learning resource to support the implementation of the nice shared decision making guideline. Pharmacoepidemiology and Drug Safety, 7 - 7. https://doi.org/10.1002/pds.5499

Background: Shared decision making (SDM) is a joint process in which a healthcare professional works together with a person to reach a decision about care1; this can help ensure care is personalised to each individual. Research shows that SDM is not... Read More about The creation of an online learning resource to support the implementation of the nice shared decision making guideline.

A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome (2022)
Journal Article
Harrington, G. M. B., Cool, P., Hulme, C., Osman, A., Chowdhury, J. R., Kumar, N., …Wright, K. (2022). A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome. arXiv, https://doi.org/10.1101/2022.07.12.499696

1Abstract1.1IntroductionSpinal Cord Injury (SCI) is a major cause of disability, with complications post-injury often leading to life-long health issues with need of extensive treatment. Neurological outcome post-SCI can be variable and difficult to... Read More about A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome.

Exploring community pharmacists' use of health literacy interventions in their everyday practice. (2022)
Journal Article
White, S., & Cork, T. (2022). Exploring community pharmacists' use of health literacy interventions in their everyday practice. Research in Social and Administrative Pharmacy, 18(11), 3948-3952. https://doi.org/10.1016/j.sapharm.2022.06.007

BACKGROUND: Limited health literacy often results in people inadequately understanding medicines-related information and subsequently not taking medicines as prescribed. Using health literacy interventions is important for community pharmacists, as t... Read More about Exploring community pharmacists' use of health literacy interventions in their everyday practice..

Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT (2022)
Journal Article
Watkins, C., Tishkovskaya, S., Brown, C., Sutton, C., Garcia, Y. S., Forshaw, D., …Panton, C. (2022). Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT. Health Technology Assessment, 26(31), 1-88. https://doi.org/10.3310/eftv1270

Background Urinary incontinence affects around half of stroke survivors in the acute phase, and it often presents as a new problem after stroke or, if pre-existing, worsens significantly, adding to the disability and helplessness caused by neurologic... Read More about Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT.

In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum (2022)
Journal Article
Okokon, J. E., Etuk, I. C., Thomas, P. S., Drijfhout, F. P., Claridge, T. D., & Li, W. (2022). In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum. Biomedicine and Pharmacotherapy, https://doi.org/10.1016/j.biopha.2022.113153

Solanum anomalum is a plant used ethnomedically for the treatment of diabetes. The study was aimed to validate ethnomedical claims in rat model and identify the likely antidiabetic compounds. Leaf extract (70–210 mg/kg/day) and fractions (140 mg/kg/d... Read More about In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum.

Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke (2022)
Thesis
Singh, A. (2022). Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke. (Thesis). Keele University

Ischaemic stroke is the most common form of stroke, accounting for appropriate 87% of all strokes. Reperfusion is the only immediate treatment option following ischaemic stroke, however, this option is only applicable to a small percentage of patient... Read More about Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke.

A multimodal approach to biomarker discovery for spinal cord injury (2022)
Thesis
Bernardo Harrington, G. M. (2022). A multimodal approach to biomarker discovery for spinal cord injury. (Thesis). Keele University

The extent of the devastating outcomes following spinal cord injury, particularly with respect to neurological function, are difficult to predict. This can make it difficult to plan clinical care and manage patient expectations, both of which can hav... Read More about A multimodal approach to biomarker discovery for spinal cord injury.

Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial. (2022)
Journal Article
Nolan. (2022). Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial. JACC: Cardiovascular Interventions, 1191 - 1201. https://doi.org/10.1016/j.jcin.2022.04.032

BACKGROUND: Currently, transradial access (TRA) is the recommended access for coronary procedures because of increased safety, with radial artery occlusion (RAO) being its most frequent complication, which will increasingly affect patients undergoing... Read More about Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial..