All Outputs (5)

Structural characterisation of the human innate immune proteins FIBCD1 and surfactant proteins A and D (2021)
Thesis
Williams, H. M. Structural characterisation of the human innate immune proteins FIBCD1 and surfactant proteins A and D. (Thesis). Keele University. https://keele-repository.worktribe.com/output/419435

The surfactant proteins A and D (SP-A and SP-D) and fibrinogen C containing domain 1 (FIBCD1) are pattern recognition receptors, which recognise pathogens through the binding of carbohydrate residues embedded within surface structures. The work prese... Read More about Structural characterisation of the human innate immune proteins FIBCD1 and surfactant proteins A and D.

Structural characterisation of human immunoglobulin G Fc fragment and its interaction with heparin (2020)
Thesis
Earps, H. F. Structural characterisation of human immunoglobulin G Fc fragment and its interaction with heparin. (Thesis). Keele University. https://keele-repository.worktribe.com/output/417399

Human immunoglobulin (Ig) G is the most commonly found class of antibody in the human body and is involved in pathogen recognition as a part of the adaptive and innate immune response. Recognition occurs through the fragment antibody binding (FAB) re... Read More about Structural characterisation of human immunoglobulin G Fc fragment and its interaction with heparin.

A multidisciplinary investigation of the relationship between 'Pseudomonas syringae' and 'Aesculus hippocastanum' bleeding canker (2020)
Thesis
Alhamd, O. A. A. A multidisciplinary investigation of the relationship between 'Pseudomonas syringae' and 'Aesculus hippocastanum' bleeding canker. (Thesis). Keele University. https://keele-repository.worktribe.com/output/421792

Bleeding canker of Aesculus hippocastanum is caused by Pseudomonas syringae pathovar aesculi. The disease has rapidly spread through many countries, yet little is known about this potentially fatal disease. Climate change affects plant diseases direc... Read More about A multidisciplinary investigation of the relationship between 'Pseudomonas syringae' and 'Aesculus hippocastanum' bleeding canker.

Investigation of modified forms of serum C-reactive protein in diabetes mellitus (2019)
Thesis
Mahmood, S. M. Investigation of modified forms of serum C-reactive protein in diabetes mellitus. (Thesis). Keele University. https://keele-repository.worktribe.com/output/414936

C-reactive protein (CRP) is known to dissociate to its monomeric subunits (mCRP) in vivo. Furthermore, hyperglycaemia associated with diabetes mellitus (DM) results in glycation of serum proteins to a various extent based on their half-life and glyca... Read More about Investigation of modified forms of serum C-reactive protein in diabetes mellitus.

Investigation of serum monomeric C-reactive protein and associated auto-antibodies in rheumatoid arthritis (2019)
Thesis
Moran, J. A. Investigation of serum monomeric C-reactive protein and associated auto-antibodies in rheumatoid arthritis. (Thesis). Keele University. https://keele-repository.worktribe.com/output/413132

The research described here considers molecular variations of the acute phase response protein, C reactive protein (CRP), and the presence of CRP and anti CRP autoantibodies in rheumatoid arthritis (RA) patient serum.
Monomeric CRP (mCRP) was genera... Read More about Investigation of serum monomeric C-reactive protein and associated auto-antibodies in rheumatoid arthritis.