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Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling (2014)
Journal Article
(2014). Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling. British Journal of Pharmacology, 3963-3979. https://doi.org/10.1111/bph.12604

The delivery of therapeutic agents is characterized by numerous challenges including poor absorption, low penetration in target tissues and non-specific dissemination in organs, leading to toxicity or poor drug exposure. Several nanomedicine strategi... Read More about Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling.

Geothermal reservoir characteristics of Meso- and Cenozoic sedimentary rocks of Budapest (Hungary) (2014)
Journal Article
(2014). Geothermal reservoir characteristics of Meso- and Cenozoic sedimentary rocks of Budapest (Hungary). Zeitschrift der Deutschen Gesellschaft für Geowissenschaften ZDGG, 487 - 493. https://doi.org/10.1127/1860-1804/2014/0069

The characterisation of deep geothermal reservoirs of sedimentary basins is supported by outcrop analogue studies since reservoir characteristics are strongly related to the sedimentary facies and thus influence the basic direction of geothermal fiel... Read More about Geothermal reservoir characteristics of Meso- and Cenozoic sedimentary rocks of Budapest (Hungary).

Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database (2014)
Journal Article
Mamas. (2014). Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database. Journal of Biomedical Research, 349 -359. https://doi.org/10.7555/JBR.28.20140045

Heart failure is common in older people and its prevalence is increasing. The Heart 'omics' in AGEing (HOMAGE) project aims to provide a biomarker approach that will improve the early diagnosis of heart failure. A large clinical database, based on (1... Read More about Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database.

Physical properties of the WASP-67 planetary system from multi-colour photometry (2014)
Journal Article
Mancini, L., Southworth, J., Ciceri, S., Calchi Novati, S., Dominik, M., Henning, T., …Wertz, O. (2014). Physical properties of the WASP-67 planetary system from multi-colour photometry. Astronomy & Astrophysics, 568, Article A127. https://doi.org/10.1051/0004-6361/201424106

Context. The extrasolar planet WASP-67 b is the first hot Jupiter definitively known to undergo only partial eclipses. The lack of the second and third contact points in this planetary system makes it difficult to obtain accurate measurements of its... Read More about Physical properties of the WASP-67 planetary system from multi-colour photometry.

Getting under the skin of the primary care consultation using video stimulated recall: a systematic review (2014)
Journal Article
Paskins, Z., McHugh, G., & Hassell, A. B. (2014). Getting under the skin of the primary care consultation using video stimulated recall: a systematic review. BMC medical research methodology, 101 -?. https://doi.org/10.1186/1471-2288-14-101

BACKGROUND: Video stimulated recall (VSR) is a method of enhancing participants' accounts of the consultation using a video recording of the event to encourage and prompt recall in a post consultation interview. VSR is used in education and education... Read More about Getting under the skin of the primary care consultation using video stimulated recall: a systematic review.

Impact of left ventricular function in relation to procedural outcomes following percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society (2014)
Journal Article
Mamas, M. A., Anderson, S. G., O'Kane, P. D., Keavney, B., Nolan, J., Oldroyd, K. G., …de Belder, M. A. (2014). Impact of left ventricular function in relation to procedural outcomes following percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society. European Heart Journal, 35(43), 3004-3012. https://doi.org/10.1093/eurheartj/ehu303

Aim Between 10 and 30% of patients undergoing percutaneous coronary intervention (PCI) have left ventricular (LV) dysfunction. We investigate the association between LV function on early and late mortality outcomes in a national ‘real-world’ cohort... Read More about Impact of left ventricular function in relation to procedural outcomes following percutaneous coronary intervention: insights from the British Cardiovascular Intervention Society.

Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical Practice Research Datalink (2014)
Journal Article
Clarson, L. E., Hider, S. L., Belcher, J., Heneghan, C., Roddy, E., & Mallen, C. D. (2014). Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, 74(4), 642-647. https://doi.org/10.1136/annrheumdis-2014-205252

Objectives To determine whether gout increases risk of incident coronary heart disease (CHD), cerebrovascular (CVD) and peripheral vascular disease (PVD) in a large cohort of primary care patients with gout, since there have been no such large studie... Read More about Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK Clinical Practice Research Datalink.

Implementing the NICE osteoarthritis guidelines: a mixed methods study and cluster randomised trial of a model osteoarthritis consultation in primary care - the Management of OsteoArthritis In Consultations (MOSAICS) study protocol (2014)
Journal Article
Dziedzic, K. S., Healey, E. L., Porcheret, M., Nio Ong, B., Main, C. J., Jordan, K. P., …Hay, E. M. (2014). Implementing the NICE osteoarthritis guidelines: a mixed methods study and cluster randomised trial of a model osteoarthritis consultation in primary care - the Management of OsteoArthritis In Consultations (MOSAICS) study protocol. Implementation Science, 9, Article 95. https://doi.org/10.1186/s13012-014-0095-y

Backgroundhere is as yet no evidence on the feasibility of implementing recommendations from the National Institute of Health and Care Excellence (NICE) osteoarthritis (OA) guidelines in primary care, or of the effect these recommendations on the con... Read More about Implementing the NICE osteoarthritis guidelines: a mixed methods study and cluster randomised trial of a model osteoarthritis consultation in primary care - the Management of OsteoArthritis In Consultations (MOSAICS) study protocol.

Reflections on mirror therapy: A systematic review of the effect of mirror visual feedback on the brain (2014)
Journal Article
Deconinck, F. J., Smorenburg, A. R., Benham, A., Ledebt, A., Feltham, M. G., & Savelsbergh, G. J. (2015). Reflections on mirror therapy: A systematic review of the effect of mirror visual feedback on the brain. Neurorehabilitation and Neural Repair, 29(4), 349-361. https://doi.org/10.1177/1545968314546134

Background. Mirror visual feedback (MVF), a phenomenon where movement of one limb is perceived as movement of the other limb, has the capacity to alleviate phantom limb pain or promote motor recovery of the upper limbs after stroke. The tool has rece... Read More about Reflections on mirror therapy: A systematic review of the effect of mirror visual feedback on the brain.

Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15 (2014)
Journal Article
Reader, K. L., Mottershead, D. G., Martin, G. A., Gilchrist, R. B., Heath, D. A., McNatty, K. P., & Juengel, J. L. (2016). Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15. Reproduction, Fertility and Development, 28(4), 491. https://doi.org/10.1071/rd14099

Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) act synergistically to regulate granulosa cell proliferation and steroid production in several species. Several non-Sma and mothers against decapentaplegic (SMAD) signal... Read More about Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15.

Bacterially synthesized ferrite nanoparticles for magnetic hyperthermia applications (2014)
Journal Article
Céspedes, E., Byrne, J. M., Farrow, N., Moise, S., Coker, V. S., Bencsik, M., …Telling, N. D. (in press). Bacterially synthesized ferrite nanoparticles for magnetic hyperthermia applications. Nanoscale, 6(21), 12958-12970. https://doi.org/10.1039/c4nr03004d

Magnetic hyperthermia uses AC stimulation of magnetic nanoparticles to generate heat for cancer cell destruction. Whilst nanoparticles produced inside magnetotactic bacteria have shown amongst the highest reported heating to date, these particles are... Read More about Bacterially synthesized ferrite nanoparticles for magnetic hyperthermia applications.

Efficacy and well-being in rural north India: the role of social identification with a large-scale community identity (2014)
Journal Article
(2014). Efficacy and well-being in rural north India: the role of social identification with a large-scale community identity. European Journal of Social Psychology, 787-798. https://doi.org/10.1002/ejsp.2060

Identifying with a group can contribute to a sense of well-being. The mechanisms involved are diverse: social identification with a group can impact individuals' beliefs about issues such as their connections with others, the availability of social s... Read More about Efficacy and well-being in rural north India: the role of social identification with a large-scale community identity.

Combining observational techniques to constrain convection in evolved massive star models (2014)
Journal Article
(2014). Combining observational techniques to constrain convection in evolved massive star models. Proceedings of the International Astronomical Union, 47-51. https://doi.org/10.1017/S1743921314006255

Recent stellar evolution computations indicate that massive stars in the range ~ 20 - 30 Msun are located in the blue supergiant (BSG) region of the Hertzsprung-Russell diagram at two different stages of their life: immediately after the main sequenc... Read More about Combining observational techniques to constrain convection in evolved massive star models.

Fixed dose-combination products in psychiatry: Systematic review and meta-analysis (2014)
Journal Article
Farooq, S., & Singh, S. P. (2015). Fixed dose-combination products in psychiatry: Systematic review and meta-analysis. Journal of Psychopharmacology, 29(5), 556-564. https://doi.org/10.1177/0269881114541016

Despite highly prevalent use of drug combinations in psychiatry, combination products are not commonly available. We aimed to systematically review the evidence for the use and efficacy of combination products in the practice of psychiatry. Systemati... Read More about Fixed dose-combination products in psychiatry: Systematic review and meta-analysis.

How do gym members engage with music during exercise? (2014)
Journal Article
Lamont. (2014). How do gym members engage with music during exercise?. Qualitative Research in Sport, Exercise and Health, 411-427. https://doi.org/10.1080/2159676x.2014.949835

Music is widely used to accompany exercise, and research has investigated its effects on a range of physical, physiological and psychological outcomes using quantitative methods. This research sought to investigate music and exercise using a qualitat... Read More about How do gym members engage with music during exercise?.

WASP-117b: a 10-day-period Saturn in an eccentric and misaligned orbit (2014)
Journal Article
Hellier, Smalley, & Maxted. (2014). WASP-117b: a 10-day-period Saturn in an eccentric and misaligned orbit. Astronomy & Astrophysics, https://doi.org/10.1051/0004-6361/201424481

We report the discovery of WASP-117b, the first planet with a period beyond 10 days found by the WASP survey. The planet has a mass of Mp = 0.2755 ± 0.0089 MJ, a radius of and is in an eccentric (e = 0.302 ± 0.023), 10.02165 ± 0.00055 d orbit around... Read More about WASP-117b: a 10-day-period Saturn in an eccentric and misaligned orbit.

High-precision photometry by telescope defocussing - VI. WASP-24, WASP-25 and WASP-26 (2014)
Journal Article
Southworth, J., Hinse, T., Burgdorf, M., Calchi Novati, S., Dominik, M., Galianni, P., …Vilela, C. (2014). High-precision photometry by telescope defocussing - VI. WASP-24, WASP-25 and WASP-26. Monthly Notices of the Royal Astronomical Society, 444(1), 776 -789. https://doi.org/10.1093/mnras/stu1492

We present time series photometric observations of 13 transits in the planetary systems WASP-24, WASP-25 and WASP-26. All three systems have orbital obliquity measurements, WASP-24 and WASP-26 have been observed with Spitzer, and WASP-25 was previous... Read More about High-precision photometry by telescope defocussing - VI. WASP-24, WASP-25 and WASP-26.