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All Outputs (1008)

Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated during an Outbreak, Venezuela, 2010 (2015)
Journal Article
Auguste, A. J., Liria, J., Giambalvo, D., Forrester, N. L., Moncada, M., Long, K. C., Morón, D., de Manzione, N., Tesh, R. B., Halsey, E. S., Kochel, T. J., Hernandez, R., Navarro, J.-C., & Weaver, S. C. (2015). Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated during an Outbreak, Venezuela, 2010. Emerging Infectious Diseases, 21(10), 1742-1750. https://doi.org/10.3201/eid2110.141660

Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform (2015)
Journal Article
Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S., George, V., Kalra, S., Kondrashov, A., Duc Hoang, M., Mosqueira, D., Patel, A., Prodanov, L., Rajamohan, D., Skarnes, W. C., Smith, J. G., & Young, L. E. (2015). Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform. BBA - Molecular Cell Research, 1863(7 Part B), 1728 - 1748. https://doi.org/10.1016/j.bbamcr.2015.10.014

Cardiomyocytes from human pluripotent stem cells (hPSCs-CMs) could revolutionise biomedicine. Global burden of heart failure will soon reach USD $90bn, while unexpected cardiotoxicity underlies 28% of drug withdrawals. Advances in hPSC isolation, Cas... Read More about Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.

Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study. (2015)
Journal Article
McLachlan, S., Mansell, G., Sanders, T., Yardley, S., van der Windt, D., Brindle, L., Chew-Graham, C., & Little, P. (2015). Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study. Family Practice, 568 - 577. https://doi.org/10.1093/fampra/cmv048

BACKGROUND: Lung and colorectal cancer are common and have high UK mortality rates. Early diagnosis is important in reducing cancer mortality, but the literature on lung and colorectal cancers suggests many people wait for a considerable time before... Read More about Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study..

The triple whammy anxiety depression and osteoarthritis in long-term conditions (2015)
Journal Article
Jinks, Chew-Graham, Mallen, & Healey. (2015). The triple whammy anxiety depression and osteoarthritis in long-term conditions. BMC Family Practice, Article 163. https://doi.org/10.1186/s12875-015-0346-2

Improving the management of people with long-term conditions is a key priority of the UK National Health Service. Whilst the coexistence of two or more long-term conditions in one person is increasingly the norm in primary care, guidelines and delive... Read More about The triple whammy anxiety depression and osteoarthritis in long-term conditions.

Research is the Future, the Future is……. (2015)
Journal Article
Gilchrist, F. J. (2015). Research is the Future, the Future is……. Paediatric Respiratory Reviews, 17, 32 - 33. https://doi.org/10.1016/j.prrv.2015.08.008

Over the past two decades, Professor Lenney has established the Paediatric Respiratory Department at the Royal Stoke University Hospital as a centre recognised for high quality research. A broad portfolio of clinical and laboratory based research is... Read More about Research is the Future, the Future is……..

Development of hand phenotypes and changes in hand pain and problems over time in older people (2015)
Journal Article
Green, D. J., Jordan, K. P., Protheroe, J., & Van Der Windt, D. A. (2015). Development of hand phenotypes and changes in hand pain and problems over time in older people. PAIN, 569-576. https://doi.org/10.1097/j.pain.0000000000000402

Hand disabilities are frequent causes of pain and disability in older people, yet knowledge regarding the characteristics and patterns of hand pain and problems over time is lacking. The main aim of this study was to identify sub-groups of older indi... Read More about Development of hand phenotypes and changes in hand pain and problems over time in older people.

Structural Insights into Separase Architecture and Substrate Recognition through Computational Modelling of Caspase-Like and Death Domains (2015)
Journal Article
Winter, A., Schmid, R., & Bayliss, R. (2015). Structural Insights into Separase Architecture and Substrate Recognition through Computational Modelling of Caspase-Like and Death Domains. PLoS Computational Biology, e1004548 - ?. https://doi.org/10.1371/journal.pcbi.1004548

Separases are large proteins that mediate sister chromatid disjunction in all eukaryotes. They belong to clan CD of cysteine peptidases and contain a well-conserved C-terminal catalytic protease domain similar to caspases and gingipains. However, unl... Read More about Structural Insights into Separase Architecture and Substrate Recognition through Computational Modelling of Caspase-Like and Death Domains.

Public entrepreneurship and the politics of regeneration in multi-Level governance (2015)
Journal Article
Catney. (2015). Public entrepreneurship and the politics of regeneration in multi-Level governance. Environment and Planning C: Government and Policy, https://doi.org/10.1177/0263774X15613357

The paper uses a case study of urban regeneration policy in Sheffield, UK, to explore local public entrepreneurship in a system of multi-level governance. Recent analyses of public entrepreneurs have directed attention to the macro-political structur... Read More about Public entrepreneurship and the politics of regeneration in multi-Level governance.

Mapping atomic and difuse interstellar band absorption across the Magellanic clouds and the Milky Way (2015)
Journal Article
Bailey, M., Van Loon, J. T., Sarre, P. J., & Beckman, J. E. (2015). Mapping atomic and difuse interstellar band absorption across the Magellanic clouds and the Milky Way. Monthly Notices of the Royal Astronomical Society, 454(4), 4013-4026. https://doi.org/10.1093/mnras/stv2178

Diffuse interstellar bands (DIBs) trace warm neutral and weakly ionized diffuse interstellar medium (ISM). Here we present a dedicated, high signal-to-noise spectroscopic survey of two of the strongest DIBs, at 5780 and 5797 Å, in optical spectra of... Read More about Mapping atomic and difuse interstellar band absorption across the Magellanic clouds and the Milky Way.

Bullying and undermining: a threat to both patient care and medical personnel wellbeing? A cross sectional survey of the Undergraduates, trainees and consultants in Obstetrics and Gynaecology in the West Midlands (2015)
Journal Article
Parry-Smith, W., Morse, L., Sutherland, A., Horrocks, P., & O’Mahony, F. (2015). Bullying and undermining: a threat to both patient care and medical personnel wellbeing? A cross sectional survey of the Undergraduates, trainees and consultants in Obstetrics and Gynaecology in the West Midlands. MedEdPublish,

The molecular characterisation of Escherichia coli K1 isolated from neonatal nasogastric feeding tubes (2015)
Journal Article
Masood. (2015). The molecular characterisation of Escherichia coli K1 isolated from neonatal nasogastric feeding tubes. BMC Infectious Diseases, https://doi.org/10.1186/s12879-015-1210-7

Background
The most common cause of Gram-negative bacterial neonatal meningitis is E. coli K1. It has a mortality rate of 10–15 %, and neurological sequelae in 30–50 % of cases. Infections can be attributable to nosocomial sources, however the pre-c... Read More about The molecular characterisation of Escherichia coli K1 isolated from neonatal nasogastric feeding tubes.

Criminal Investigation Through the Eye of the Detective: Technological Innovation and Tradition (2015)
Journal Article
(2015). Criminal Investigation Through the Eye of the Detective: Technological Innovation and Tradition. Surveillance & Society, https://doi.org/10.24908/ss.v13i3/4.5403

Technological elements and scientific knowledge are steadily transforming both the traditional image of the detective and the nature of contemporary police work. However, despite the potential utility of scientific methods and new technologies in cri... Read More about Criminal Investigation Through the Eye of the Detective: Technological Innovation and Tradition.