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Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents (2018)
Journal Article
Reynisson, J. (2018). Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents. Molecules, https://doi.org/10.3390/molecules23010145

It is now established that the thieno[2,3-b]pyridines are a potent class of antiproliferatives. One of the main issues encountered for their clinical application is their low water solubility. In order to improve this, two strategies were pursued. Fi... Read More about Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

Enhanced Collision Avoidance for Distributed LTE Vehicle to Vehicle Broadcast Communications (2018)
Journal Article
Fan. (2018). Enhanced Collision Avoidance for Distributed LTE Vehicle to Vehicle Broadcast Communications. IEEE Communications Letters, 630 - 633. https://doi.org/10.1109/LCOMM.2018.2791399

In this letter, we investigate the distributed autonomous resource selection for LTE vehicle to vehicle (V2V) broadcast. The effectiveness of collision avoidance and location based resource allocation enhancements is examined. It is found that collis... Read More about Enhanced Collision Avoidance for Distributed LTE Vehicle to Vehicle Broadcast Communications.

Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up. (2018)
Journal Article
Stynes, S., Konstantinou, K., Ogollah, R., Hay, E. M., & Dunn, K. M. (2018). Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up. PAIN, 159(4), https://doi.org/10.1097/j.pain.0000000000001147

Traditionally, low back-related leg pain (LBLP) is diagnosed clinically as referred leg pain or sciatica (nerve root involvement). However, within the spectrum of LBLP, we hypothesised that there may be other unrecognised patient subgroups. This stud... Read More about Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up..

HumanMethylation450K Array–Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer (2018)
Journal Article
Kitchen, M. O., Bryan, R. T., Emes, R. D., Luscombe, C. J., Cheng, K., Zeegers, M. P., …Fryer, A. A. (2018). HumanMethylation450K Array–Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer. Biomarkers in Cancer, 10, 1179299X1775192. https://doi.org/10.1177/1179299x17751920

Background: High-risk non-muscle invasive bladder cancer (HR-NMIBC) is a clinically unpredictable disease. Despite clinical risk estimation tools, many patients are undertreated with intra-vesical therapies alone, whereas others may be over-treated... Read More about HumanMethylation450K Array–Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer.

Plasticity within the niche ensures the maintenance of aSox2+stem cell population in the mouse incisor. (2018)
Journal Article
(2018). Plasticity within the niche ensures the maintenance of aSox2+stem cell population in the mouse incisor. Development, https://doi.org/10.1242/dev.155929

In mice, the incisors grow throughout the animal's life, and this continuous renewal is driven by dental epithelial and mesenchymal stem cells.Sox2is a principal marker of the epithelial stem cells that reside in the mouse incisor stem cell niche, ca... Read More about Plasticity within the niche ensures the maintenance of aSox2+stem cell population in the mouse incisor..

Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database (2018)
Journal Article
Mamas. (2018). Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database. American Heart Journal, 46-54. https://doi.org/10.1016/j.ahj.2018.01.001

Aims Access site choice for cases requiring rotational atherectomy (PCI-ROTA) is poorly defined. Using the British Cardiovascular Intervention Society PCI database, temporal changes and contemporary associates/outcomes of access site choice for PCI-... Read More about Temporal changes in radial access use, associates and outcomes in patients undergoing PCI using rotational atherectomy between 2007 and 2014: results from the British Cardiovascular Intervention Society national database.

Kant’s Critique Of Religion: Epistemic Sources Of Secularism (2018)
Journal Article
Baiasu. (2018). Kant’s Critique Of Religion: Epistemic Sources Of Secularism. Diametros: A Journal of Philosophy, 7-29. https://doi.org/10.13153/diam.54.2017.1131

The secular interpretation of Kant is widespread and Kant is viewed as the most prestigious founding father of liberal secularism. At the same time, however, commentators note that Kant’s position on secularism is in fact much more complex, and some... Read More about Kant’s Critique Of Religion: Epistemic Sources Of Secularism.

An excess of massive stars in the local 30 Doradus starburst (2018)
Journal Article
Schneider, F. R. N., Sana, H., Evans, C. J., Bestenlehner, J. M., Castro, N., Fossati, L., …Norman, C. (2018). An excess of massive stars in the local 30 Doradus starburst. Science, 359(6371), 69-71. https://doi.org/10.1126/science.aan0106

The 30 Doradus star-forming region in the Large Magellanic Cloud is a nearby analog of large star-formation events in the distant universe. We determined the recent formation history and the initial mass function (IMF) of massive stars in 30 Doradus... Read More about An excess of massive stars in the local 30 Doradus starburst.

A deep X-ray view of the bare AGN Ark120. IV. XMM-Newton and NuSTAR spectra dominated by two temperature (warm, hot) Comptonization processes (2018)
Journal Article
(2018). A deep X-ray view of the bare AGN Ark120. IV. XMM-Newton and NuSTAR spectra dominated by two temperature (warm, hot) Comptonization processes. Astronomy & Astrophysics, A42 -?. https://doi.org/10.1051/0004-6361/201731290

We perform an X-ray spectral analysis of the brightest and cleanest bare AGN known so far, Ark 120, in order to determine the process(es) at work in the vicinity of the SMBH. We present spectral analysis of data from an extensive campaign observing A... Read More about A deep X-ray view of the bare AGN Ark120. IV. XMM-Newton and NuSTAR spectra dominated by two temperature (warm, hot) Comptonization processes.

A survey of general practitioners' attitudes towards psychiatry. (2018)
Journal Article
(2018). A survey of general practitioners' attitudes towards psychiatry. https://doi.org/10.1192/pb.bp.109.027896

Aims and method There is a lack of current data regarding attitudes of doctors towards psychiatry. General practitioners (GPs) are increasingly involved in teaching psychiatry, and their attitudes towards psychiatry may affect their ability to promo... Read More about A survey of general practitioners' attitudes towards psychiatry..

Perspectives on supporting fathers affected by postnatal depression and a history of violence (2018)
Journal Article
Laws, T., & Keeling, J. (2018). Perspectives on supporting fathers affected by postnatal depression and a history of violence. Journal of Health Visiting, 6(1), 40-47. https://doi.org/10.12968/johv.2018.6.1.40

Intimate partner violence in the perinatal period is a significant problem that remains underscreened, underdiagnosed and undertreated. The establishment of evidence-based guidelines to enable health visitors to identify couples experiencing violence... Read More about Perspectives on supporting fathers affected by postnatal depression and a history of violence.

Adopting an Open Innovation Program with Supply Chain Management in China: A Case Study (2018)
Journal Article
Lau, A. K. W., Lee, L. W. Y., Lai, K., & Lee, P. K. C. (2018). Adopting an Open Innovation Program with Supply Chain Management in China: A Case Study. Engineering Management Journal, 30(1), 24-41. https://doi.org/10.1080/10429247.2017.1408387

This study examines how an open innovation program can be implemented in practice by a foreign company operating in China with due consideration of traditional supply chain management practices. A case study of an open innovation initiative in a reno... Read More about Adopting an Open Innovation Program with Supply Chain Management in China: A Case Study.

Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. (2018)
Journal Article
Choudry, A., & Farooq, S. (2018). Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. BJPsych Bulletin, 345 - 352. https://doi.org/10.1192/pb.bp.116.055269

Aims and method To review the literature to examine the factors that may be affecting recruitment into psychiatry in the UK. We systematically searched four databases to identify studies from 1974 to 2016 and identified 27 papers that met the specifi... Read More about Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views..

Risk of cancer in patients with psoriasis on biological therapies: a systematic review (2018)
Journal Article
Peleva, E., Exton, L. S., Kelley, K., Kleyn, C. E., Mason, K. J., & Smith, C. H. (2018). Risk of cancer in patients with psoriasis on biological therapies: a systematic review. British Journal of Dermatology, 178(1), 103-113. https://doi.org/10.1111/bjd.15830

Background Biological therapies are highly effective in psoriasis, but have profound effects on innate and adaptive immune pathways that may negatively impact on cancer immunosurveillance mechanisms. Objectives To investigate the risk of cancer... Read More about Risk of cancer in patients with psoriasis on biological therapies: a systematic review.

Hemiarthroplasty proximal femoral endoprostheses following tumour reconstruction: is acetabular replacement necessary? (2018)
Journal Article
Stevenson, J. D., Kumar, V. S., Cribb, G. L., & Cool, P. (2018). Hemiarthroplasty proximal femoral endoprostheses following tumour reconstruction: is acetabular replacement necessary?. The Bone & Joint Journal, 100-B(1), 101-108. https://doi.org/10.1302/0301-620x.100b1.bjj-2017-0005.r1

Aims Dislocation rates are reportedly lower in patients requiring proximal femoral hemiarthroplasty than for patients undergoing hip arthroplasty for neoplasia. Without acetabular replacement, pain due to acetabular wear necessitating revision surge... Read More about Hemiarthroplasty proximal femoral endoprostheses following tumour reconstruction: is acetabular replacement necessary?.

Mosquito bottlenecks alter viral mutant swarm in a tissue and time-dependent manner with contraction and expansion of variant positions and diversity (2018)
Journal Article
Patterson, E. I., Khanipov, K., Rojas, M. M., Kautz, T. F., Rockx-Brouwer, D., Golovko, G., …Forrester, N. L. (2018). Mosquito bottlenecks alter viral mutant swarm in a tissue and time-dependent manner with contraction and expansion of variant positions and diversity. Virus Evolution, 4(1), https://doi.org/10.1093/ve/vey001