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Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line (2018)
Journal Article
Haga, I. R., Simpson, J. L., Hawes, P. C., & Beard, P. M. (2018). Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line. Scientific Reports, 8, Article 16956. https://doi.org/10.1038/s41598-018-34732-w

The re-emergence of poxviral zoonotic infections and the threat of bioterrorism emphasise the demand for efective antipoxvirus therapies. Here, we show that carbenoxolone, a pharmacological inhibitor of gap junction function and a compound widely... Read More about Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line.

Optimizing outcomes for ankylosing spondylitis and axial spondyloarthritis patients: a holistic approach to care. (2018)
Journal Article
(2018). Optimizing outcomes for ankylosing spondylitis and axial spondyloarthritis patients: a holistic approach to care. Rheumatology, vi29 - vi34. https://doi.org/10.1093/rheumatology/key200

Axial SpA (axSpA) can affect diverse elements of an individual's life. The areas affected can be much more wide-ranging than the historical medical model of SpA, causing increased disease activity (pain and stiffness) and disability (reduced range of... Read More about Optimizing outcomes for ankylosing spondylitis and axial spondyloarthritis patients: a holistic approach to care..

Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts (2018)
Journal Article
Shoaib, A., Kinnaird, T., Curzen, N., Kontopantelis, E., Ludman, P., de Belder, M., …Mamas, M. (2018). Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts. Circulation: Cardiovascular Interventions, 11(11), https://doi.org/10.1161/circinterventions.118.006824

Background: There are limited data on outcomes of patients with previous CABG presenting with NSTEMI undergoing PCI. We compare clinical characteristics and outcomes in NSTEMI patients undergoing PCI with or without prior CABG surgery in a national c... Read More about Outcomes Following Percutaneous Coronary Intervention (PCI) in Non-ST-segment Elevation Myocardial Infarction Patients with Coronary Artery Bypass Grafts.

Design of a chiral elastic structure supporting interfacial waveforms (2018)
Journal Article
Nieves. (2018). Design of a chiral elastic structure supporting interfacial waveforms. https://doi.org/10.1109/MetaMaterials.2018.8534138

An infinite heterogeneous elastic triangular lattice connected to a non-uniform array of gyroscopic spinners is considered. An algorithm is described for generating interfacial waves that propagate along the boundaries of subdomains containing inhomo... Read More about Design of a chiral elastic structure supporting interfacial waveforms.

FAST Phase III RCT of Radiotherapy Hypofractionation for Treatment of Early Breast Cancer: 10-Year Results (CRUKE/04/015) (2018)
Journal Article
Brunt, A., Haviland, J., Sydenham, M., Algurafi, H., Alhasso, A., Bliss, P., …Yarnold, J. (2018). FAST Phase III RCT of Radiotherapy Hypofractionation for Treatment of Early Breast Cancer: 10-Year Results (CRUKE/04/015). International Journal of Radiation Oncology - Biology - Physics, 102(5), 1603 -1604. https://doi.org/10.1016/j.ijrobp.2018.08.049

Conference abstract.

A Perfusion Culture System for Assessing Bone Marrow Stromal Cell Differentiation on PLGA Scaffolds for Bone Repair (2018)
Journal Article
(2018). A Perfusion Culture System for Assessing Bone Marrow Stromal Cell Differentiation on PLGA Scaffolds for Bone Repair. Frontiers in Bioengineering and Biotechnology, 161 -161. https://doi.org/10.3389/fbioe.2018.00161

Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone ma... Read More about A Perfusion Culture System for Assessing Bone Marrow Stromal Cell Differentiation on PLGA Scaffolds for Bone Repair.

Consolidation of pathology services in England: have savings been achieved? (2018)
Journal Article
(2018). Consolidation of pathology services in England: have savings been achieved?. BMC Health Services Research, https://doi.org/10.1186/s12913-018-3683-8

Background: During the last decade, pathology services in England have undergone profound changes with an extensive consolidation of laboratories. This has been driven by some national reviews forecasting a national reduction of costs by £250–£500 mi... Read More about Consolidation of pathology services in England: have savings been achieved?.

The cryptotephra record of the Marine Isotope Stage 12 to 10 interval (460–335 ka) at Tenaghi Philippon, Greece: Exploring chronological markers for the Middle Pleistocene of the Mediterranean region (2018)
Journal Article
Gertisser. (2018). The cryptotephra record of the Marine Isotope Stage 12 to 10 interval (460–335 ka) at Tenaghi Philippon, Greece: Exploring chronological markers for the Middle Pleistocene of the Mediterranean region. Quaternary Science Reviews, 313-333. https://doi.org/10.1016/j.quascirev.2018.09.019

Precise chronologies that allow direct correlation of paleoclimate archives are a prerequisite for deciphering the spatiotemporal characteristics of short-term climate variability. Such chronologies can be established through the analysis of tephra l... Read More about The cryptotephra record of the Marine Isotope Stage 12 to 10 interval (460–335 ka) at Tenaghi Philippon, Greece: Exploring chronological markers for the Middle Pleistocene of the Mediterranean region.

Provenance information recorded by mineral inclusions in detrital garnet (2018)
Journal Article
(2018). Provenance information recorded by mineral inclusions in detrital garnet. Sedimentary Geology, 32-49. https://doi.org/10.1016/j.sedgeo.2018.07.009

Garnet single-grain analysis is an often used and well established tool in sedimentary provenance studies, especially when metamorphic source rocks are involved. So far, however, solely the geochemical composition of detrital garnets is considered to... Read More about Provenance information recorded by mineral inclusions in detrital garnet.

The impact of diabetes on the prognostic value of left ventricular function following percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society. (2018)
Journal Article
Mamas, & Rashid. (2018). The impact of diabetes on the prognostic value of left ventricular function following percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society. Catheterization and Cardiovascular Interventions, 393-402. https://doi.org/10.1002/ccd.27642

Objectives To study the relationship between diabetes mellitus (DM) and left ventricular (LV) function on outcomes following percutaneous coronary intervention (PCI). Background Methods DM is a growing public health challenge worldwide and a signific... Read More about The impact of diabetes on the prognostic value of left ventricular function following percutaneous coronary intervention: Insights from the British Cardiovascular Intervention Society..

The Elicitation and Management of Multiple Health Concerns in GP Consultations (2018)
Journal Article
Chew-Graham. (2018). The Elicitation and Management of Multiple Health Concerns in GP Consultations. Patient Education and Counseling, https://doi.org/10.1016/j.pec.2018.11.009

Objective To describe the nature of patient concerns and to explore if, when and how they are addressed by GPs in the UK. Methods Detailed coding and descriptive analysis of 185 video recordings from the EPaC study (Elicitation of Patient Concer... Read More about The Elicitation and Management of Multiple Health Concerns in GP Consultations.

Geophysical assessment of illegally buried toxic waste for a legal enquiry: A case study in Northern Ireland (UK) (2018)
Journal Article
Ruffell, A., Pringle, J. K., Graham, C., Langton, M., & Jones, G. M. (2018). Geophysical assessment of illegally buried toxic waste for a legal enquiry: A case study in Northern Ireland (UK). Environmental Forensics, 19(4), 239-252. https://doi.org/10.1080/15275922.2018.1519740

Buried illegal waste and uncontrolled legal waste dumps are a major problem throughout the world, both in developing and more economically developed countries. Criminal investigations can effectively use geoscience investigations to assist them to be... Read More about Geophysical assessment of illegally buried toxic waste for a legal enquiry: A case study in Northern Ireland (UK).

Sonic Spectres: Word Ghosts in Madeleine Thien's Dogs at the Perimeter and the digital map project, 'Fictional Montreal/Montreal fictif' (2018)
Journal Article
Morgan. (2018). Sonic Spectres: Word Ghosts in Madeleine Thien's Dogs at the Perimeter and the digital map project, 'Fictional Montreal/Montreal fictif'. The London Journal of Canadian Studies, 40-57. https://doi.org/10.14324/111.444.ljcs.2018v33.004

This article analyses various ghosts and their connections with the unsaid and said in relation to Madeleine Thien’s Dogs at the Perimeter (2011) and the digital map project, ‘Fictional Montreal/Montréal fictif’ (Morgan and Lichti, 2016-17). Drawing... Read More about Sonic Spectres: Word Ghosts in Madeleine Thien's Dogs at the Perimeter and the digital map project, 'Fictional Montreal/Montreal fictif'.

Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene (2018)
Journal Article
(2018). Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene. Climate of the Past, 1727 -1738. https://doi.org/10.5194/cp-14-1727-2018

The Amundsen Sea Low (ASL) plays a major role in the climate and environment of Antarctica and the Southern Ocean, including surface air temperature and sea ice concentration changes. Unfortunately, a relative dearth of observational data across the... Read More about Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene.

Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene (2018)
Journal Article
(2018). Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene. Climate of the Past Discussions, 1727-1738. https://doi.org/10.5194/cp-2018-11

The Amundsen Sea Low (ASL) plays a major role in the climate and environment of Antarctica and the Southern Ocean, including surface air temperature and sea ice concentration changes. Unfortunately, a relative dearth of observational data across the... Read More about Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene.

The annual, temporal and spatial pattern of Setaria tundra outbreaks in Finnish reindeer: a mechanistic transmission model approach (2018)
Journal Article
Haider, N., Laaksonen, S., Kjær, L. J., Oksanen, A., & Bødker, R. (in press). The annual, temporal and spatial pattern of Setaria tundra outbreaks in Finnish reindeer: a mechanistic transmission model approach. Parasites and Vectors, 11, Article 565. https://doi.org/10.1186/s13071-018-3159-z

Background In northern Finland (Lapland), reindeer are reared as semi-domesticated animals. The region has a short summer season of 2–3 months, yet reindeer are infected with the mosquito-borne filarioid parasite Setaria tundra. The infection causes... Read More about The annual, temporal and spatial pattern of Setaria tundra outbreaks in Finnish reindeer: a mechanistic transmission model approach.

Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies (2018)
Journal Article
Martinengo, L., Olsson, M., Bajpai, R., Soljak, M., Upton, Z., Schmidtchen, A., …Jarbrink, K. (2019). Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies. Annals of Epidemiology, 29, 8 - 15. https://doi.org/10.1016/j.annepidem.2018.10.005

Purpose Chronic wounds are a major public health challenge, but little is known about the true burden with studies reporting different estimates because of disparities in study designs and measurement methods. This hampers efficient resource allocat... Read More about Prevalence of chronic wounds in the general population: systematic review and meta-analysis of observational studies.

Discovery of WASP-174b: Doppler tomography of a near-grazing transit (2018)
Journal Article
Maxted, Hellier, & Smalley. (2018). Discovery of WASP-174b: Doppler tomography of a near-grazing transit. Monthly Notices of the Royal Astronomical Society, 5307-5313. https://doi.org/10.1093/mnras/sty2197

We report the discovery and tomographic detection of WASP-174b, a planet with a near-grazing transit on a 4.23-d orbit around a V = 11.9, F6V star with [Fe/H] = 0.09 ± 0.09. The planet is in a moderately misaligned orbit with a sky-projected spin–orb... Read More about Discovery of WASP-174b: Doppler tomography of a near-grazing transit.