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Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic Memory (2018)
Journal Article
(2018). Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic Memory. bioRxiv, https://doi.org/10.1101/465708

Transcriptome wide changes in human skeletal muscle after acute (anabolic) and chronic resistance exercise (RE) induced hypertrophy have been extensively determined in the literature. We have also recently undertaken DNA methylome analysis (850,000 +... Read More about Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic Memory.

X-ray powder diffraction study of the stability of clathrate hydrates in the presence of salts with relevance to the Martian cryosphere (2018)
Journal Article
Safi, E., Thompson, S. P., Evans, A., Day, S. J., Murray, C. A., Baker, A. R., …Van Loon, J. T. (2019). X-ray powder diffraction study of the stability of clathrate hydrates in the presence of salts with relevance to the Martian cryosphere. Geochimica et Cosmochimica Acta, 245, 304-315. https://doi.org/10.1016/j.gca.2018.10.034

Water on the present day Martian surface is thought to exist in two thermally distinct sub-surface reservoirs: as ice in the cryosphere and as groundwater located deeper in the crust. These sub-surface environments are thought to contain saline, rath... Read More about X-ray powder diffraction study of the stability of clathrate hydrates in the presence of salts with relevance to the Martian cryosphere.

From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents (2018)
Journal Article
Lam, N. Y. S., Truong, D., Burmeister, H., Babak, M. V., Holtkamp, H. U., Movassaghi, S., …Hartinger, C. G. (2018). From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents. Inorganic Chemistry, 57(22), 14427-14434. https://doi.org/10.1021/acs.inorgchem.8b02634

Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action (2018)
Journal Article
(2018). Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, https://doi.org/10.1186/s13223-018-0305-2

Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only two aluminium salts which are used in clinically-approved vaccines, Alhydrogel® and AdjuPhos®, while the novel aluminium adjuvant used in Gardasil® is a sulphated... Read More about Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action.

Improving Shared Decision Making Between Patients and Clinicians: Design and Development of a Virtual Patient Simulation Tool. (2018)
Journal Article
Jacklin, S., Maskrey, N., & Chapman, S. (2018). Improving Shared Decision Making Between Patients and Clinicians: Design and Development of a Virtual Patient Simulation Tool. JMIR Medical Education, e10088 - ?. https://doi.org/10.2196/10088

BACKGROUND: Shared decision making (SDM) involves the formation of a collaborative partnership between the patient and clinician combining both of their expertise in order to benefit decision making. In order for clinicians to be able to carry out th... Read More about Improving Shared Decision Making Between Patients and Clinicians: Design and Development of a Virtual Patient Simulation Tool..

The success of university law schools in England and Wales: or how to fail (2018)
Journal Article
(2018). The success of university law schools in England and Wales: or how to fail. The Law Teacher, 490 -498. https://doi.org/10.1080/03069400.2018.1529278

University law schools in England and Wales presently have a very successful model for providing undergraduate education. This model allows them to discharge their duties with respect to both teaching and research. Providing they are careful in their... Read More about The success of university law schools in England and Wales: or how to fail.

Acute flares of knee osteoarthritis in primary care: a feasibility and pilot case-crossover study (2018)
Journal Article
Thomas, M., Butler-Walley, S., Rathod-Mistry, T., Mayson, Z., Parry, E., Pope, C., …Peat, G. (2018). Acute flares of knee osteoarthritis in primary care: a feasibility and pilot case-crossover study. Pilot and Feasibility Studies, 4, Article 167. https://doi.org/10.1186/s40814-018-0359-4

Background: Osteoarthritis (OA) is a leading cause of persistent pain and disability. Traditionally viewed as a slowly progressive disease, the impact of symptom variability on prognosis remains unclear. 'Acute-on-chronic' episodes are a well-recogni... Read More about Acute flares of knee osteoarthritis in primary care: a feasibility and pilot case-crossover study.

The Success of University Law Schools in England and Wales: Or How to Fail (2018)
Journal Article
(2018). The Success of University Law Schools in England and Wales: Or How to Fail. The Law Teacher, 490-498. https://doi.org/10.1080/03069400.2018.1529278

University law schools in England and Wales presently have a very successful model for providing undergraduate education. This model allows them to discharge their duties with respect to both teaching and research. Providing they are careful in their... Read More about The Success of University Law Schools in England and Wales: Or How to Fail.

Protocol for a randomized controlled trial of the Breaking Free Online Health and Justice program for substance misuse in prison settings (2018)
Journal Article
(2018). Protocol for a randomized controlled trial of the Breaking Free Online Health and Justice program for substance misuse in prison settings. Health and Justice, https://doi.org/10.1186/s40352-018-0078-1

Background Substance misuse, including problematic drug and alcohol use, are significant issues in society that can have multiple detrimental effects. Many people access support for their substance misuse during prison sentences, due to the associat... Read More about Protocol for a randomized controlled trial of the Breaking Free Online Health and Justice program for substance misuse in prison settings.

Peer assisted learning in pharmacy: The mentor and student perspective (2018)
Journal Article
Micallef, R., & Slater, N. (2018). Peer assisted learning in pharmacy: The mentor and student perspective. Pharmacy Education, 18,

Introduction: Peer assisted learning (PAL) was introduced into a 2nd year pharmacy cohort (n=160) using older students as mentors. Participation in PAL was voluntary. Aim: This study aims to evaluate the Pharmacy Law PAL sessions, from both the st... Read More about Peer assisted learning in pharmacy: The mentor and student perspective.

Correction to Lancet Public Health 2018; 3: 567–75 (2018)
Journal Article
Kontopantelis, E., Buchan, I., Webb, R. T., Ashcroft, D. M., Mamas, M. A., & Doran, T. (2018). Correction to Lancet Public Health 2018; 3: 567–75. The Lancet Public Health, 3(12), e566. https://doi.org/10.1016/s2468-2667%2818%2930231-7

Kontopantelis E, Buchan I, Webb RT, Ashcroft DM, Mamas MA, Doran T. Disparities in mortality among 25–44-year-olds in England: a longitudinal population-based study. Lancet Public Health 2018; 3: 567–75—In figure 5 of this Article, the labels on the... Read More about Correction to Lancet Public Health 2018; 3: 567–75.

'So many women suffer in silence': a thematic analysis of women's written accounts of coping with endometriosis. (2018)
Journal Article
Grogan, S., Turley, E., & Cole, J. (2018). 'So many women suffer in silence': a thematic analysis of women's written accounts of coping with endometriosis. Psychology and Health, 1364 - 1378. https://doi.org/10.1080/08870446.2018.1496252

OBJECTIVE: To understand women's experiences of coping with endometriosis, and impact on their lives. DESIGN: Women accessed an online questionnaire through a U.K.-based endometriosis charity website. METHODS: Thirty-four women, aged 22-56 years, wit... Read More about 'So many women suffer in silence': a thematic analysis of women's written accounts of coping with endometriosis..

One-Year Outcomes after PCI Strategies in Cardiogenic Shock. (2018)
Journal Article
Mamas. (2018). One-Year Outcomes after PCI Strategies in Cardiogenic Shock. New England Journal of Medicine, 1699 - 1710. https://doi.org/10.1056/NEJMoa1808788

BACKGROUND: Among patients with acute myocardial infarction, cardiogenic shock, and multivessel coronary artery disease, the risk of a composite of death from any cause or severe renal failure leading to renal-replacement therapy at 30 days was found... Read More about One-Year Outcomes after PCI Strategies in Cardiogenic Shock..

Quo Vadis EU Investment Law and Policy? The Shaky Path Towards the International Promotion of EU Rules (2018)
Journal Article
(2018). Quo Vadis EU Investment Law and Policy? The Shaky Path Towards the International Promotion of EU Rules. European Foreign Affairs Review, https://doi.org/10.2139/ssrn.3527604

Following the Lisbon changes to the EU’s Common Commercial Policy (CCP), the path was set for the EU to conclude international agreements that cover the protection of foreign direct investment and to participate in international investment law (IIL)... Read More about Quo Vadis EU Investment Law and Policy? The Shaky Path Towards the International Promotion of EU Rules.

Single-atom vacancy in monolayer phosphorene: A comprehensive study of stability and magnetism under applied strain (2018)
Journal Article
Abreu Da Silva Morbec, J. M., Rahman, G., & Kratzer, P. (2018). Single-atom vacancy in monolayer phosphorene: A comprehensive study of stability and magnetism under applied strain. Journal of Magnetism and Magnetic Materials, 546 -553. https://doi.org/10.1016/j.jmmm.2018.06.016

Using first-principles calculations based on density-functional theory we systematically investigate the effect of applied strain on the stability and on the electronic and magnetic properties of monolayer phosphorene with single-atom vacancy. We con... Read More about Single-atom vacancy in monolayer phosphorene: A comprehensive study of stability and magnetism under applied strain.

Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT. (2018)
Journal Article
Chew-Graham. (2018). Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT. Health Technology Assessment, 1 - 136. https://doi.org/10.3310/hta22630

BACKGROUND: Depression is usually managed in primary care and antidepressants are often the first-line treatment, but only half of those treated respond to a single antidepressant. OBJECTIVES: To investigate whether or not combining mirtazapine with... Read More about Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT..

Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death (2018)
Journal Article
Morgan, C., Webb, R. T., Carr, M. J., Kontopantelis, E., Chew-Graham, C. A., Kapur, N., & Ashcroft, D. M. (2018). Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death. The Lancet Psychiatry, 905-912. https://doi.org/10.1016/S2215-0366%2818%2930348-1

BACKGROUND: Self-harm is a major risk factor for suicide, with older adults (older than 65 years) having reportedly greater suicidal intent than any other age group. With the aging population rising and paucity of research focus in this age group, th... Read More about Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death.