All Outputs (1493)

Are Anticholinergic Symptoms a Risk Factor for Falls in Older General Practice Patients With Polypharmacy?: Study Protocol for the Development and Validation of a Prognostic Model (2021)
Journal Article
(2021). Are Anticholinergic Symptoms a Risk Factor for Falls in Older General Practice Patients With Polypharmacy?: Study Protocol for the Development and Validation of a Prognostic Model. Frontiers in Pharmacology, 577747 -?. https://doi.org/10.3389/fphar.2020.577747

Background: Cumulative anticholinergic exposure, also known as anticholinergic burden, is associated with a variety of adverse outcomes. However, studies show that anticholinergic effects tend to be underestimated by prescribers, and anticholinergics... Read More about Are Anticholinergic Symptoms a Risk Factor for Falls in Older General Practice Patients With Polypharmacy?: Study Protocol for the Development and Validation of a Prognostic Model.

TESS Hunt for Young and Maturing Exoplanets (THYME). IV. Three Small Planets Orbiting a 120 Myr Old Star in the Pisces-Eridanus Stream (2021)
Journal Article
Newton, E. R., Mann, A. W., Kraus, A. L., Livingston, J. H., Vanderburg, A., Curtis, J. L., Thao, P. C., Hawkins, K., Wood, M. L., Rizzuto, A. C., Soubkiou, A., Tofflemire, B. M., Zhou, G., Crossfield, I. J. M., Pearce, L. A., Collins, K. A., Conti, D. M., Tan, T.-G., Villeneuva, S., Spencer, A., …Latham, D. W. (2021). TESS Hunt for Young and Maturing Exoplanets (THYME). IV. Three Small Planets Orbiting a 120 Myr Old Star in the Pisces-Eridanus Stream. Astronomical Journal, 161(2), Article ARTN 65. https://doi.org/10.3847/1538-3881/abccc6

Young exoplanets can offer insight into the evolution of planetary atmospheres, compositions, and architectures. We present the discovery of the young planetary system TOI 451 (TIC 257605131, Gaia DR2 4844691297067063424). TOI 451 is a member of the... Read More about TESS Hunt for Young and Maturing Exoplanets (THYME). IV. Three Small Planets Orbiting a 120 Myr Old Star in the Pisces-Eridanus Stream.

Improving osteoarthritis management in primary healthcare: results from a quasi-experimental study (2021)
Journal Article
Osteras, N., Blaker, I. B., Hjortland, T., Cottrell, E., Quicke, J. G., Dziedzic, K. S., Blackburn, S., & Paulsen, A. (2021). Improving osteoarthritis management in primary healthcare: results from a quasi-experimental study. BMC Musculoskeletal Disorders, 22(1), Article 79. https://doi.org/10.1186/s12891-021-03959-6

BACKGROUND: To improve quality of care for patients with hip and knee osteoarthritis (OA), general practitioners (GPs) and physiotherapists (PTs) in a Norwegian municipality initiated an intervention. The intervention aimed to increase provision of c... Read More about Improving osteoarthritis management in primary healthcare: results from a quasi-experimental study.

Project Assessment: An international perspective (2021)
Journal Article
(2021). Project Assessment: An international perspective. Scholarship of Teaching and Learning in Psychology, 185-197. https://doi.org/10.1037/stl0000217

Project Assessment is an American Psychological Association (APA, 2018) initiative aimed at facilitating assessment of the five Comprehensive Learning Goals of the APA Guidelines for the Undergraduate Psychology Major (2013). We believe that Project... Read More about Project Assessment: An international perspective.

What is the optimum rehabilitation for patients who have undergone release procedures for frozen shoulder? A UK survey (2021)
Journal Article
Willmore, E., McRobert, C., Foy, C., Stratton, I., & van der Windt, D. (2021). What is the optimum rehabilitation for patients who have undergone release procedures for frozen shoulder? A UK survey. Musculoskeletal Science and Practice, 52, 102319. https://doi.org/10.1016/j.msksp.2021.102319

Despite usually being considered necessary, the rehabilitation regime that optimises outcomes for patients following release procedures for frozen shoulder has not been established and no accepted best practice guidelines currently exist. The purpose... Read More about What is the optimum rehabilitation for patients who have undergone release procedures for frozen shoulder? A UK survey.

Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach? (2021)
Journal Article
Garcia, J., McCarthy, H. S., Kuiper, J. H., Melrose, J., & Roberts, S. (2021). Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?. Biomolecules, 11(1), Article ARTN 92. https://doi.org/10.3390/biom11010092

Articular cartilage is considered to have limited regenerative capacity, which has led to the search for therapies to limit or halt the progression of its destruction. Perlecan, a multifunctional heparan sulphate (HS) proteoglycan, promotes embryonic... Read More about Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?.

Growth rates of accessory human enamel: a histological case study of a modern-day incisor from Northern England (2021)
Journal Article
Aris, C., & Street, E. (2021). Growth rates of accessory human enamel: a histological case study of a modern-day incisor from Northern England. Dental Anthropology, 34(1), https://doi.org/10.26575/daj.v34i1.312

This study investigates enamel growth of a modern-day human upper first incisor (S197) possessing an accessory cusp. Growth rates collected from the accessory enamel are compared to data collected from the primary cusp and healthy incisors from the s... Read More about Growth rates of accessory human enamel: a histological case study of a modern-day incisor from Northern England.

Towards consensus in defining and handling contextual factors within rheumatology trials: an initial qualitative study from an OMERACT working group (2021)
Journal Article
Nielsen, S. M., Uggen Rasmussen, M., Boers, M., A van der Windt, D., de Wit, M., G Woodworth, T., A Flurey, C., Beaton, D., Shea, B., Escorpizo, R., Furst, D. E., Smolen, J. S., Toupin-April, K., Boonen, A., Voshaar, M., Ellingsen, T., Wells, G. A., Reeves, B. C., March, L., Tugwell, P., & Christensen, R. (2021). Towards consensus in defining and handling contextual factors within rheumatology trials: an initial qualitative study from an OMERACT working group. Annals of the Rheumatic Diseases, 80(2), 242-249. https://doi.org/10.1136/annrheumdis-2020-217895

The Outcome Measures in Rheumatology Initiative established the Contextual Factors Working Group to guide the understanding, identification and handling of contextual factors for clinical trials. In clinical research, different uses of the term ‘cont... Read More about Towards consensus in defining and handling contextual factors within rheumatology trials: an initial qualitative study from an OMERACT working group.

Transient ultrasound stimulation has lasting effects on neuronal excitability (2021)
Journal Article
Clennell, B., Steward, T. G., Elley, M., Shin, E., Weston, M., Drinkwater, B. W., & Whitcomb, D. J. (2021). Transient ultrasound stimulation has lasting effects on neuronal excitability. Brain Stimulation, 14(2), 217-225. https://doi.org/10.1016/j.brs.2021.01.003

Background
Transcranial ultrasound stimulation can acutely modulate brain activity, but the lasting effects on neurons are unknown.

Objective
To assess the excitability profile of neurons in the hours following transient ultrasound stimulation.... Read More about Transient ultrasound stimulation has lasting effects on neuronal excitability.

E-transparency and government budgetary corruption: A social marketing and transformation case from Nigeria (2021)
Journal Article
Olarewaju, T., Rufai, I., & Gallage, S. (2021). E-transparency and government budgetary corruption: A social marketing and transformation case from Nigeria. The Electronic Journal of Information Systems in Developing Countries, 87(3), https://doi.org/10.1002/isd2.12167

This article shows how Information and Communication Technology (ICT), incorporating social media, can lead to accountability and transparency in a government's budget. Specifically, it examined how a Non-Governmental Organization (NGO) used ICT to f... Read More about E-transparency and government budgetary corruption: A social marketing and transformation case from Nigeria.

An optimised MALDI-TOF assay for phosphatidylcholine-specific phospholipase C. (2021)
Journal Article
Reynisson. (2021). An optimised MALDI-TOF assay for phosphatidylcholine-specific phospholipase C. Analytical Methods, https://doi.org/10.1039/D0AY02208J

The Bacillus cereus phosphatidylcholine-specific phospholipase C (PC-PLCBc) is an enzyme that catalyses the hydrolysis of phosphatidylcholines into phosphocholine and 1,2-diacylglycerols. PC-PLCBc has found applications in both the food industry and... Read More about An optimised MALDI-TOF assay for phosphatidylcholine-specific phospholipase C..

Serum lithium test requesting across three UK regions: an evaluation of adherence to monitoring guidelines (2021)
Journal Article
Parfitt, C., Duff, C. J., Scargill, J., Green, L., Holland, D., Heald, A. H., & Fryer, A. A. (2021). Serum lithium test requesting across three UK regions: an evaluation of adherence to monitoring guidelines. BMC Psychiatry, 21, Article 32. https://doi.org/10.1186/s12888-020-03023-y

BACKGROUND: Bipolar disorder is the fourth most common mental health condition, affecting ~?1% of UK adults. Lithium is an effective treatment for prevention of relapse and hospital admission, and is widely recommended as a first-line treatment. We p... Read More about Serum lithium test requesting across three UK regions: an evaluation of adherence to monitoring guidelines.

Anomalous Low Thermal Conductivity of Atomically Thin InSe Probed by Scanning Thermal Microscopy (2021)
Journal Article
Mazumder, D., Castanon, E., D. Kovalyuk, Z., Kolosov, O., Kazakova, O., Tzalenchuk, A., Patanè, A., Balakrishnan, N., Nilanthy, B., Vincent, T., Buckley, D., & R. Kudrynskyi, Z. (2021). Anomalous Low Thermal Conductivity of Atomically Thin InSe Probed by Scanning Thermal Microscopy. Advanced functional materials, 31(11), Article 2008967. https://doi.org/10.1002/adfm.202008967

The ability of a material to conduct heat influences many physical phenomena, ranging from thermal management in nanoscale devices to thermoelectrics. Van der Waals two dimensional (2D) materials offer a versatile platform to tailor heat transfer due... Read More about Anomalous Low Thermal Conductivity of Atomically Thin InSe Probed by Scanning Thermal Microscopy.

Towards engineering manufacturing systems for mass personalisation: a stigmergic approach (2021)
Journal Article
Ogunsakin, R., Marin, C. A., & Mehandjiev, N. (2021). Towards engineering manufacturing systems for mass personalisation: a stigmergic approach. International Journal of Computer Integrated Manufacturing, 34(4), 341-369. https://doi.org/10.1080/0951192x.2020.1858508

Mass personalisation is characterised by unpredicted changes in product design and manufacturing processes, as a result of customers’ ability to co-create and co-design products based on personal preferences. Previous approaches that address such unp... Read More about Towards engineering manufacturing systems for mass personalisation: a stigmergic approach.

Nanostructural deformation of high-stiffness spruce wood under tension. (2021)
Journal Article
(2021). Nanostructural deformation of high-stiffness spruce wood under tension

Conifer wood is an exceptionally stiff and strong material when its cellulose microfibrils are well aligned. However, it is not well understood how the polymer components cellulose, hemicelluloses and lignin co-operate to resist tensile stress in woo... Read More about Nanostructural deformation of high-stiffness spruce wood under tension..

Towards Estimation of Emotions From Eye Pupillometry With Low-Cost Devices (2021)
Journal Article
Rafique, S., Fleury, M., Kanwal, N., Karamat, I., & Asghar, M. (2021). Towards Estimation of Emotions From Eye Pupillometry With Low-Cost Devices. IEEE Access, 5354 - 5370. https://doi.org/10.1109/access.2020.3048311

Emotional care is important for some patients and their caregivers. Within a clinical or home care situation, technology can be employed to remotely monitor the emotional response of such people. This paper considers pupillometry as a non-invasive wa... Read More about Towards Estimation of Emotions From Eye Pupillometry With Low-Cost Devices.

Continual updating and monitoring of clinical prediction models: time for dynamic prediction systems? (2021)
Journal Article
(2021). Continual updating and monitoring of clinical prediction models: time for dynamic prediction systems?. Diagnostic and Prognostic Research, 1 - ?. https://doi.org/10.1186/s41512-020-00090-3

Clinical prediction models (CPMs) have become fundamental for risk stratification across healthcare. The CPM pipeline (development, validation, deployment, and impact assessment) is commonly viewed as a one-time activity, with model updating rarely c... Read More about Continual updating and monitoring of clinical prediction models: time for dynamic prediction systems?.

Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: a population-based cohort study (2021)
Journal Article
Chew-Graham, C. (2021). Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: a population-based cohort study. The Lancet Public Health, https://doi.org/10.1016/S2468-2667%2820%2930288-7

BACKGROUND: The COVID-19 pandemic has adversely affected population mental health. We aimed to assess temporal trends in primary care-recorded common mental illness, episodes of self-harm, psychotropic medication prescribing, and general practitioner... Read More about Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: a population-based cohort study.

Assessing Sampling Error in Pseudo-Panel Models (2021)
Journal Article
Khan, R. (2021). Assessing Sampling Error in Pseudo-Panel Models. Oxford Bulletin of Economics and Statistics, 83(3), 742-769. https://doi.org/10.1111/obes.12416

While pseudo-panels are useful when only repeated cross-section data are available, estimates are likely to be attenuated and suffer from sampling error if cell sizes (number of individuals grouped together in a cohort) are too few. However, there is... Read More about Assessing Sampling Error in Pseudo-Panel Models.

Biological Flora of the British Isles: Crataegus laevigata (2021)
Journal Article
Thomas, P. A., Leski, T., La Porta, N., Dering, M., & Iszkulo, G. (2021). Biological Flora of the British Isles: Crataegus laevigata. Journal of Ecology, 109(1), 572-596. https://doi.org/10.1111/1365-2745.13541

This account presents information on all aspects of the biology of Crataegus laevigata (Poir.) DC (Midland hawthorn) (C. oxyacanthoides Thuill.) that are relevant to understanding its ecological characteristics and behaviour. The main topics are pres... Read More about Biological Flora of the British Isles: Crataegus laevigata.