All Outputs (2)

Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment (2013)
Journal Article
Balami, J. S., Fricker, R. A., & Chen, R. (2013). Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment. CNS & Neurological Disorders - Drug Targets, 12(2), 209 -219. https://doi.org/10.2174/1871527311312020007

No pharmacological intervention has been shown convincingly to improve neurological outcome in stroke patients after the brain tissue is infarcted. While conventional therapeutic strategies focus on preventing brain damage, stem cell treatment has th... Read More about Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment.

Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease.
Journal Article
Mitchell​, W. D., Orme, R. P., Hart, S. R., & Fricker, R. A. (2018). Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease. PeerJ PrePrints, https://doi.org/10.7287/peerj.preprints.26443v2

Parkinson’s disease is a widespread condition caused by degeneration of dopamine neurons in the midbrain. A number of proteins are known to be important to signalling mechanisms present in the midbrain during natural dopamine neuron development, an... Read More about Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease..