All Outputs (2)

Coordination chemistry of a fused triazolopyrazine ligand favoring structural anion···π interactions (2025)
Journal Article
King, A. D., Woodfine, S. E., & Hawes, C. S. (in press). Coordination chemistry of a fused triazolopyrazine ligand favoring structural anion···π interactions. Journal of Coordination Chemistry, 1-12. https://doi.org/10.1080/00958972.2024.2445214

The fused heterocyclic ligand 1,2,4-triazolo[4,3-a]pyrazine (L1) is a rigid heterocyclic building block capable of pyrazolate-like coordination modes while retaining neutral electronic character. Here, we examine the coordination chemistry of this sp... Read More about Coordination chemistry of a fused triazolopyrazine ligand favoring structural anion···π interactions.

Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger. (2022)
Journal Article
Luo, J., Mobley, R., Woodfine, S., Drijfhout, F., Horrocks, P., Ren, X., & Li, W. (2022). Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger. Applied Microbiology and Biotechnology, 106, 2433-2444. https://doi.org/10.1007/s00253-022-11888-0

Artemisinin is a component part of current frontline medicines for the treatment of malaria. The aim of this study is to make analogues of artemisinin using microbial transformation and evaluate their in vitro antimalarial activity. A panel of microo... Read More about Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger..