Characterization of a K<inf>ATP</inf> channel-independent pathway involved in potentiation of insulin secretion by efaroxan
(2001)
Journal Article
Chan, S. L., Mourtada, M., & Morgan, N. G. (2001). Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan. Diabetes, 50(2), 340–347. https://doi.org/10.2337/diabetes.50.2.340
Efaroxan, like several other imidazoline reagents, elicits a glucose-dependent increase in insulin secretion from pancreatic β-cells. This response has been attributed to efaroxan-mediated blockade of KATP channels, with the subsequent gating of volt... Read More about Characterization of a K<inf>ATP</inf> channel-independent pathway involved in potentiation of insulin secretion by efaroxan.