All Outputs (67)

Urban Metabolism: An integrated approach to exploring the challenges of resource management for urban sustainability in developing countries (2021)
Thesis
Khalifa, Y. A. (2021). Urban Metabolism: An integrated approach to exploring the challenges of resource management for urban sustainability in developing countries. (Thesis). Keele University

Driven by climate change and scarcity of resources, resource management has become crucial for urban sustainability worldwide. There is an increasing interest in urban metabolism as a concept as it enables researchers to identify environment-related... Read More about Urban Metabolism: An integrated approach to exploring the challenges of resource management for urban sustainability in developing countries.

The formation of a cross-town Multi-Academy Trust: A case of policy enactment in the local organisation of education (2021)
Thesis
Hay, A. L. (2021). The formation of a cross-town Multi-Academy Trust: A case of policy enactment in the local organisation of education. (Thesis). Keele University

This research investigates two high schools and one middle school in the grip of a seismic policy change as they set aside generations of rivalry to work together as a newly formed Multi-Academy Trust (MAT). It adopts an insider case study approach;... Read More about The formation of a cross-town Multi-Academy Trust: A case of policy enactment in the local organisation of education.

Investigation into the role of long non-coding RNAs in neuroblastoma and glioma (2021)
Thesis
Bountali, A. (2021). Investigation into the role of long non-coding RNAs in neuroblastoma and glioma. (Thesis). Keele University

Long non-coding RNAs (lncRNAs) play key roles in several processes in healthy and cancer settings and the underpinning mechanisms of their action are thoroughly investigated. In line with this, this study investigates the role of the lncRNA myocardia... Read More about Investigation into the role of long non-coding RNAs in neuroblastoma and glioma.

4:23 PM, Relaxant (2021)
Thesis
Bolger, L. S. A. (2021). 4:23 PM, Relaxant. (Thesis). Keele University

The practical component of this thesis is a collection of poems entitled 4:23 PM, Relaxant, which consists of an original collection of verse written mainly in the confessional tradition. The collection addresses a number of themes including family a... Read More about 4:23 PM, Relaxant.

Treaties as a central diplomatic tool in the ‘legal’ pacification, and colonisation of the Western Lower Niger, 1884-1914 (2021)
Thesis
Ariye, E. C. (2021). Treaties as a central diplomatic tool in the ‘legal’ pacification, and colonisation of the Western Lower Niger, 1884-1914. (Thesis). Keele University

This thesis is a case study of Great Britain’s colonisation of a few indigenous, contiguous peoples of the Western Lower Niger from 1884 to 1914. These are the Itsekiri, the Western Ijo, the Urhobo, the Isoko and the Ukwuani of present-day Delta Stat... Read More about Treaties as a central diplomatic tool in the ‘legal’ pacification, and colonisation of the Western Lower Niger, 1884-1914.

Exploring the securitisation of climate change within the meaning of Article 39: mapping the narratives of UN Security Council intervention (2021)
Thesis
Murphy, A. (2021). Exploring the securitisation of climate change within the meaning of Article 39: mapping the narratives of UN Security Council intervention. (Thesis). Keele University

The IPCC is unequivocal that climate change is happening, and its consequences will continue to be devastating for the earth and humanity. The inadequacy of international climate law to mitigate the threat, makes it essential that we search for ways... Read More about Exploring the securitisation of climate change within the meaning of Article 39: mapping the narratives of UN Security Council intervention.

Livelihoods, vulnerability, and adaptation to climate change of small-holder farmers in Kilimanjaro, Tanzania (2021)
Thesis
Mwasha, S. I. (2021). Livelihoods, vulnerability, and adaptation to climate change of small-holder farmers in Kilimanjaro, Tanzania. (Thesis). Keele University

Climate change is expected to reduce food security in many African countries, and yield from rain-fed agriculture is projected to decline significantly. Future warming will persist even if current agreements on emission controls are put into action b... Read More about Livelihoods, vulnerability, and adaptation to climate change of small-holder farmers in Kilimanjaro, Tanzania.

Architectural elements in fluvial multi-storey sandbodies: deposition, preservation and numerical representation (2021)
Thesis
Mitten, A. J. (2021). Architectural elements in fluvial multi-storey sandbodies: deposition, preservation and numerical representation. (Thesis). Keele University

The recoverable proportion of known mobile resources from fluvial multi-storey sandbodies (MSBs) reservoirs is relatively low. The low recovery proportion can be attributed to a lack of a three-dimensional understanding of the reservoir architecture,... Read More about Architectural elements in fluvial multi-storey sandbodies: deposition, preservation and numerical representation.

Investigating health and work participation in later working life: multi-state modelling of Healthy Working Life Expectancy using national population datasets (2021)
Thesis
Parker, M. E. (2021). Investigating health and work participation in later working life: multi-state modelling of Healthy Working Life Expectancy using national population datasets. (Thesis). Keele University

Introduction Retirement ages are rising in many countries due to population ageing and increasing life expectancy. It is unclear whether people in later working life (age =50) are able to work for longer due to health conditions and a lack of job op... Read More about Investigating health and work participation in later working life: multi-state modelling of Healthy Working Life Expectancy using national population datasets.

Exploring the usage of edge gradients within images to perform coarse localisation (2021)
Thesis
Jarvis, D. G. (2021). Exploring the usage of edge gradients within images to perform coarse localisation. (Thesis). Keele University

With the rise in autonomous systems being integrated into the world around us, it has become increasingly important that theses systems have functions that allow the navigation of environments. One of the key functions is the recognition of the envir... Read More about Exploring the usage of edge gradients within images to perform coarse localisation.

The impact of guidelines on the use of imaging in osteoarthritis: a time trend analysis using electronic health record data (2021)
Thesis
Henry-Blake, C. J. (2021). The impact of guidelines on the use of imaging in osteoarthritis: a time trend analysis using electronic health record data. (Thesis). Keele University

The National Institute for Health and Care Excellence (NICE) suggests there is no role for routine radiography in the diagnosis of osteoarthritis (OA). It is not known how consistent this recommendation is across guidelines, or the impact of guidelin... Read More about The impact of guidelines on the use of imaging in osteoarthritis: a time trend analysis using electronic health record data.

Preparation and structural studies of halogen bonded co-crystals (2021)
Thesis
Mahmood, A. S. M. (2021). Preparation and structural studies of halogen bonded co-crystals. (Thesis). Keele University

The project investigates the reactions of selected aromatic nitrogen compounds with selected di- and interhalogens in order to obtain crystalline N···I halogen-bonded complexes according to the equation: A + B ? AB where reactant A is a pyridine... Read More about Preparation and structural studies of halogen bonded co-crystals.

The meaning of life: a defence of the question’s legitimacy and routes towards ultimate meaning (2021)
Thesis
Fox, J. (2021). The meaning of life: a defence of the question’s legitimacy and routes towards ultimate meaning. (Thesis). Keele University

This dissertation establishes and defends three positions: (1) The question ‘What is the meaning of life?’ is a request for a global-metaphysical explanation for life and existence that narrates across those elements of most existential import to hum... Read More about The meaning of life: a defence of the question’s legitimacy and routes towards ultimate meaning.

Physical activity in people with osteoarthritis and comorbidity: a multi-method study (2021)
Thesis
McKevitt, S. (2021). Physical activity in people with osteoarthritis and comorbidity: a multi-method study. (Thesis). Keele University

Osteoarthritis (OA) is common and associated with one of the highest comorbidity rates. OA clinical guidelines recommend physical activity (PA) as core treatment, irrespective of comorbidity. However, no current synthesis of the effectiveness of PA f... Read More about Physical activity in people with osteoarthritis and comorbidity: a multi-method study.

Evaluation of surgical outcomes using administrative hospital data (2021)
Thesis
El-Dhuwaib, Y. (2021). Evaluation of surgical outcomes using administrative hospital data. (Thesis). Keele University

Hospital Episode Statistics (HES) is the main hospital administrative dataset in England. Since the early 1990s HES has been used for research. The aim of the thesis is to evaluate the use of HES data to measure surgical outcomes. Objectives: 1.... Read More about Evaluation of surgical outcomes using administrative hospital data.

A multi-methods study of the factors influencing the adoption of proprotein convertase subtilisin/kexin-type 9 (PCSK9) inhibitors (2021)
Thesis
Odingo, M. O. (2021). A multi-methods study of the factors influencing the adoption of proprotein convertase subtilisin/kexin-type 9 (PCSK9) inhibitors. (Thesis). Keele University

Introduction A new class of lipid lowering agent Proprotein Convertase Subtilisin/Kexin Type 9 inhibitors (PCSK9) was launched in 2015 for the treatment of heterozygous familial hypercholesterolemia (HeFH) in combination with statin therapy. There a... Read More about A multi-methods study of the factors influencing the adoption of proprotein convertase subtilisin/kexin-type 9 (PCSK9) inhibitors.

Investigation of correlation of biochemical marker expression and mechanical properties of preterm membranes (2021)
Thesis
Bhunia, S. (2021). Investigation of correlation of biochemical marker expression and mechanical properties of preterm membranes. (Thesis). Keele University

The fetal membrane surrounds and supports the developing fetus during the pregnancy. The cellular structure of the fetal membrane and the proteins synthesized by the cells of amniotic and chorionic membranes, maintain the mechanical integrity of the... Read More about Investigation of correlation of biochemical marker expression and mechanical properties of preterm membranes.

Dopaminergic modulation of activity dependent synaptic plasticity in rodent lateral entorhinal cortex (2021)
Thesis
Wells, T. R. (2021). Dopaminergic modulation of activity dependent synaptic plasticity in rodent lateral entorhinal cortex. (Thesis). Keele University

The entorhinal cortex serves as the interface region between allocortical input and the hippocampus, with current theories suggesting that the region is involved in memory encoding, with dopamine serving as a “motivational currency” provided to memor... Read More about Dopaminergic modulation of activity dependent synaptic plasticity in rodent lateral entorhinal cortex.

Nicotinamide, neural cells, and Parkinson’s disease: exploring nicotinamide’s effects on proliferation, neuronal differentiation, and neuroprotection within in vitro models (2021)
Thesis
Green, E. L. (2021). Nicotinamide, neural cells, and Parkinson’s disease: exploring nicotinamide’s effects on proliferation, neuronal differentiation, and neuroprotection within in vitro models. (Thesis). Keele University

Parkinson’s disease (PD) is characterised by motor symptoms caused by degeneration of dopaminergic neurons in the substantia nigra. The cause remains elusive and current treatments cannot halt or reverse progression. This thesis explores the effects... Read More about Nicotinamide, neural cells, and Parkinson’s disease: exploring nicotinamide’s effects on proliferation, neuronal differentiation, and neuroprotection within in vitro models.

Balancing value and effort: a classic grounded theory of frontline police practice (2021)
Thesis
Ash, D. P. (2021). Balancing value and effort: a classic grounded theory of frontline police practice. (Thesis). Keele University

This thesis seeks to explain the behaviour of frontline police officers engaged in incident work. Policymakers try to improve police legitimacy by changing how individual police officers interact with the public at police incidents. However, police p... Read More about Balancing value and effort: a classic grounded theory of frontline police practice.