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All Outputs (60)

A genealogy of rights: emancipatory rights-claiming as a conscious act of freedom (2022)
Thesis
Holder, S. D. (2022). A genealogy of rights: emancipatory rights-claiming as a conscious act of freedom. (Thesis). Keele University

This project seeks to excavate and explore the emancipatory potential of rights and rights language. Public international law, and its most powerful normative concept, sovereignty, helped manufacture a distinct brand of freedom and equality in the ro... Read More about A genealogy of rights: emancipatory rights-claiming as a conscious act of freedom.

Heparin: an established anticoagulant drug with therapeutic potential for COVID-19 (2022)
Thesis
McIntosh, O. G. (2022). Heparin: an established anticoagulant drug with therapeutic potential for COVID-19. (Thesis). Keele University

The biologically and medically important heparan sulphate and heparin polysaccharides have been previously shown to mediate viral cell entry for enveloped viruses. Furthermore, heparin and its analogues have been shown to have anti-inflammatory and a... Read More about Heparin: an established anticoagulant drug with therapeutic potential for COVID-19.

Sustainable integration: an ethnographic study of a British Muslim community in Birmingham (2022)
Thesis
Elsayed, S. (2022). Sustainable integration: an ethnographic study of a British Muslim community in Birmingham. (Thesis). Keele University

Drawing upon ethnographic research undertaken in an area of Birmingham, this thesis investigates meanings and understandings of integration in a community deemed nonintegrated, namely the Muslim community. Exploring real-world stories and mundane exp... Read More about Sustainable integration: an ethnographic study of a British Muslim community in Birmingham.

The relative dominance of allo-controls and local-scale sedimentary processes upon preserved successions of aeolian-marine margins (2022)
Thesis
Cross, S. L. (2022). The relative dominance of allo-controls and local-scale sedimentary processes upon preserved successions of aeolian-marine margins. (Thesis). Keele University

The sedimentology, controls and efficiency of central erg environments are wellconstrained, however marginal relationships are less understood and often underrepresented. The Moab Member of the Curtis Formation is a well-exposed, laterally continuous... Read More about The relative dominance of allo-controls and local-scale sedimentary processes upon preserved successions of aeolian-marine margins.

Secondary transfer effect and intergroup solidarity: alternative processes of generalisation (2022)
Thesis
Unver, H. (2022). Secondary transfer effect and intergroup solidarity: alternative processes of generalisation. (Thesis). Keele University

Through a series of six studies (Studies 1, 5, and 6 involves two groups), this thesis focuses on a relatively understudied dimension of intergroup contact, i.e. secondary transfer effect (STE; Pettigrew, 2009). More specifically, the thesis investig... Read More about Secondary transfer effect and intergroup solidarity: alternative processes of generalisation.

Ecoaesthetics: Environmental aesthetics and Kant's deduction (2022)
Thesis
Kings, A. E. (2022). Ecoaesthetics: Environmental aesthetics and Kant's deduction. (Thesis). Keele University

This thesis is designed to develop an understanding of the problems, limitations and potential uses of Kant's aesthetic deduction. Motivated by an interest in environmental aesthetics, this thesis offers a critical analysis of Kantian aesthetics in o... Read More about Ecoaesthetics: Environmental aesthetics and Kant's deduction.

Determining the role of epigenetics in telomerase regulation (2022)
Thesis
Dogan, F. (2022). Determining the role of epigenetics in telomerase regulation. (Thesis). Keele University

Telomeres are guanine-rich 5'-TTAGGG-3' repeats found at the ends of human chromosomes that protect chromosomes from degradation and also provide stabilization. Telomerase macromolecule is the primary enzyme responsible for telomere elongation. Telom... Read More about Determining the role of epigenetics in telomerase regulation.

Coloniality, expert knowledges and the 'war on terror': a survey of three think tanks' discourses 2001-2015 (2022)
Thesis
Khan, S. (2022). Coloniality, expert knowledges and the 'war on terror': a survey of three think tanks' discourses 2001-2015. (Thesis). Keele University

Informed by the critique of Eurocentrism in the discipline of International Relations, this thesis investigates the relationship between knowledge production defined as expertise, the ‘global war on terror’, and coloniality. It conducts a critical su... Read More about Coloniality, expert knowledges and the 'war on terror': a survey of three think tanks' discourses 2001-2015.

The Photograph Superiority Effect: Investigating the role of stimulus format and distinctiveness in recognition (2022)
Thesis
Adams, J. (2022). The Photograph Superiority Effect: Investigating the role of stimulus format and distinctiveness in recognition. (Thesis). Keele University

Stimuli presented as pictures are recognised better than those presented as words (Paivio, Rogers, & Smythe, 1968; Shepard, 1967). Numerous theoretical accounts have been proposed to explain this robust Picture Superiority Effect (PSE), though incons... Read More about The Photograph Superiority Effect: Investigating the role of stimulus format and distinctiveness in recognition.

Non-anticoagulant glycosaminoglycan extracts isolated from aquatic species inhibit BACE-1: a key drug target in Alzheimer’s Disease (2022)
Thesis
Mycroft-West, C. J. (2022). Non-anticoagulant glycosaminoglycan extracts isolated from aquatic species inhibit BACE-1: a key drug target in Alzheimer’s Disease. (Thesis). Keele University

Currently, only palliative drugs are available for the treatment of Alzheimer’s disease, therefore there is an urgent need to develop therapeutics targeting the underlying aetiology of the disease. The clinical anticoagulant heparin has previously be... Read More about Non-anticoagulant glycosaminoglycan extracts isolated from aquatic species inhibit BACE-1: a key drug target in Alzheimer’s Disease.

Military logistics and supply during the British Civil Wars, 1638–1653 (2022)
Thesis
Price, G. W. (2022). Military logistics and supply during the British Civil Wars, 1638–1653. (Thesis). Keele University

The aim of this thesis is to analyse the logistics and supply systems of the armies during the British Civil Wars at an operational level. Current historical works have neglected to fully evaluate the events of the British Civil Wars with respect to... Read More about Military logistics and supply during the British Civil Wars, 1638–1653.

Radical idealism and empirical metaphysics in the work of Mary Baker Eddy (2022)
Thesis
Sheldon, N. D. (2022). Radical idealism and empirical metaphysics in the work of Mary Baker Eddy. (Thesis). Keele University

The nineteenth-century American, Mary Baker Eddy, is well known in the United States for having founded the religion Christian Science, but she is not generally regarded as philosopher, let alone an original one. This dissertation argues that she is... Read More about Radical idealism and empirical metaphysics in the work of Mary Baker Eddy.

Impulsive-compulsive behaviours in Parkinson’s disease: a behavioural, neuroimaging and neurophysiological investigation (2022)
Thesis
Martini, A. (2022). Impulsive-compulsive behaviours in Parkinson’s disease: a behavioural, neuroimaging and neurophysiological investigation. (Thesis). Keele University

Background: Persons with Parkinson’s (PwP) may develop Impulsivecompulsive behaviours (ICBs) as side-effect of dopamine replacement therapy (DRT). The unresolved question addressed by this thesis is why only some PwP develop ICBs. This is an importan... Read More about Impulsive-compulsive behaviours in Parkinson’s disease: a behavioural, neuroimaging and neurophysiological investigation.

An in vitro study of the modulation of astrocytes in the blood brain barrier during human cerebral malaria (2022)
Thesis
Ogbolosingha, A. J. (2022). An in vitro study of the modulation of astrocytes in the blood brain barrier during human cerebral malaria. (Thesis). Keele University

Cerebral malaria (CM) is the most life-threatening complication of Plasmodium falciparum (Pf) infection. A key hallmark of CM is the sequestration of Pf infected red blood cells (PRBC) to the human brain endothelial cells (HBEC) of the blood brain ba... Read More about An in vitro study of the modulation of astrocytes in the blood brain barrier during human cerebral malaria.

Neuroevolution of bipedal locomotion: algorithmic, balance penalty and morphological improvements for improved robustness and performance (2022)
Thesis
Jackson, B. (2022). Neuroevolution of bipedal locomotion: algorithmic, balance penalty and morphological improvements for improved robustness and performance. (Thesis). Keele University

Bipedalism is theorised to have emerged in humans in order to enable endurance running and tool use via the hands. It is one of the most complex styles of locomotion, with agents typically having a high center of mass and two feet very close together... Read More about Neuroevolution of bipedal locomotion: algorithmic, balance penalty and morphological improvements for improved robustness and performance.

User-centred design of bedside clinical guidelines for mobile devices (2022)
Thesis
Mitchell, J. A. (2022). User-centred design of bedside clinical guidelines for mobile devices. (Thesis). Keele University

Local point of care clinical guidelines exist in numerous formats and cover a variety of clinical information, normally created on a national and local level. They are generally available as basic web pages, PDFs or documents. Despite widespread avai... Read More about User-centred design of bedside clinical guidelines for mobile devices.

From quarks to cognition: in pursuit of a complete micropsychist theory of consciousness (2022)
Thesis
Hibbert, B. J. (2022). From quarks to cognition: in pursuit of a complete micropsychist theory of consciousness. (Thesis). Keele University

Despite having received a recent resurgence of interest, Panpsychism remains a worldview afflicted by various explanatory shortfalls. Chiefly, the literature is yet to provide a ‘proper’ panpsychist theory of consciousness with the potential to expla... Read More about From quarks to cognition: in pursuit of a complete micropsychist theory of consciousness.

Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke (2022)
Thesis
Singh, A. (2022). Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke. (Thesis). Keele University

Ischaemic stroke is the most common form of stroke, accounting for appropriate 87% of all strokes. Reperfusion is the only immediate treatment option following ischaemic stroke, however, this option is only applicable to a small percentage of patient... Read More about Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke.

Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis (2022)
Thesis
Burgess, R. M. (2022). Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis. (Thesis). Keele University

Introduction: High quality data on service performance is essential in healthcare. There is however a paucity of publicly reported data in community/primary care musculoskeletal (MSK) services. There is also a lack of guidance on which metrics servic... Read More about Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis.