All Outputs (1608)

Best interests decisions for people with advanced dementia: a qualitative study of nurses’ perspectives in England (2023)
Thesis

In the United Kingdom (UK), there are 907,900 people aged over 65 with dementia, 546,500 of whom would be classed as having severe dementia (Wittenberg et al 2019). Advanced dementia is now recognised as a leading cause of death in the UK and across... Read More about Best interests decisions for people with advanced dementia: a qualitative study of nurses’ perspectives in England.

The impact on patients of pharmacist-conducted domiciliary COPD annual reviews: a qualitative study (2023)
Thesis

Introduction Globally, Chronic Obstructive Pulmonary Disease (COPD) is one of the most important non-communicable diseases with a progressive downhill course.1 Guidelines recommend regular review of patients with COPD.2 In the UK traditionally, ann... Read More about The impact on patients of pharmacist-conducted domiciliary COPD annual reviews: a qualitative study.

Using the solid injection technique with gas chromatography and mass spectrometry to identify cuticular hydrocarbons in several thrips insect species (2023)
Thesis

Thrips are a group of insects included in the order Thysanoptera. So far, over 6000 species have been described, among which over 100 are known as crop pests There is a plethora of studies on various species of thrips, yet the CHC composition is know... Read More about Using the solid injection technique with gas chromatography and mass spectrometry to identify cuticular hydrocarbons in several thrips insect species.

Constructing and maintaining a ‘noncriminal’ identity: a psychosocial narrative inquiry into the lives of people with convictions (2023)
Thesis

Despite burgeoning interest in the field of collateral consequences research, there is little empirical research exploring the subjective experiences of people living with convictions (PWCs), particularly within the jurisdiction of England and Wales.... Read More about Constructing and maintaining a ‘noncriminal’ identity: a psychosocial narrative inquiry into the lives of people with convictions.

Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling (2023)
Thesis

Fibroblast growth factors (FGFs) are polypeptide growth factors and are potent regulators of cell proliferation, cell differentiation, cell migration and angiogenesis (Ornitz and Itoh, 2001). FGFs can bind with fibroblast growth factor receptors with... Read More about Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling.

Part 1 - Scenes from the Storm Andrew Jackson - The Road to the Presidency A Drama. Part 2 - The Story of the Storm: Issues of History, Genre, and Truth in Scenes from the Storm (2023)
Thesis

‘Andrew Jackson, I am given to understand, was a patriot and a traitor. He was one of the greatest of generals, and wholly ignorant of the art of war. A writer brilliant, elegant, eloquent, and without being able to compose a correct sentence, or spe... Read More about Part 1 - Scenes from the Storm Andrew Jackson - The Road to the Presidency A Drama. Part 2 - The Story of the Storm: Issues of History, Genre, and Truth in Scenes from the Storm.

Modelling and forecasting oil market volatility: A regime switching GARCH MIDAS approach (2023)
Thesis

In this thesis, we consider a regime switching GARCH MIDAS model with Student-t innovations. By allowing the error term to be non-Gaussian, we want to see how effective it is in describing the volatility displayed in financial time series. For the lo... Read More about Modelling and forecasting oil market volatility: A regime switching GARCH MIDAS approach.

Organising to win: the role of trade union leadership in the 2016-17 Mixed Fleet Unite-British Airways dispute (2023)
Thesis

The purpose of this thesis is to add to the industrial relations literature on strikes by conducting a case study of the 2016-17 Mixed Fleet – BA industrial dispute and answer the principal research question: How do trade union workplace representati... Read More about Organising to win: the role of trade union leadership in the 2016-17 Mixed Fleet Unite-British Airways dispute.

Natural variations in egg hatching behaviour and selection of novel slowhatching strains for male anopheline deployment (2023)
Thesis

Genetic Mosquito mass release is a promising tool in the suppression of wild Anopheles gambiae sensu lato mosquitoes as part of malaria control in Africa. This tool requires a plethora number of eggs and a strain with good fitness. Thus, the success... Read More about Natural variations in egg hatching behaviour and selection of novel slowhatching strains for male anopheline deployment.

Association of frailty status with the causes, characteristics and outcomes of patients with cardiovascular disease using electronic health record data (2023)
Thesis

Introduction Cardiovascular disease (CVD) is the commonest cause of morbidity and mortality worldwide. Frailty is a clinical syndrome of physiological decline, resulting in adverse health outcomes. While the bidirectional relationship between CVD a... Read More about Association of frailty status with the causes, characteristics and outcomes of patients with cardiovascular disease using electronic health record data.

Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study (2023)
Thesis

Introduction The incidence of type 2 Diabetes mellitus (T2DM) is increasing and is a major public health burden. Obesity is one of the main modifiable risk factors for T2DM. However no UK studies have assessed the relationship of orlistat, a medica... Read More about Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study.

Reformative perspective on the principle of legitimate expectation in Turkish administrative law (2023)
Thesis

This PhD thesis aims to reform the principle of legitimate expectation in Turkish Administrative Law by considering European Union Law, decisions of the European Court of Human Rights (ECtHR), and utilizing Hohfeld analysis. The narrow interpretation... Read More about Reformative perspective on the principle of legitimate expectation in Turkish administrative law.

The potential for compression garments to influence upper limb function in children with unilateral spastic cerebral palsy (2023)
Thesis

Cerebral palsy (CP) is an umbrella term that describes a group of people with various motor, sensory and mental dysfunctions caused by permanent damage to the developing brain. Depending on the location and size of the brain damage, signs and symptom... Read More about The potential for compression garments to influence upper limb function in children with unilateral spastic cerebral palsy.

Squaring the Adoption Triangle: reconciling the competing needs of sibling children (2023)
Thesis

Siblings are important – so far, so obvious – and yet the sibling relationship does not feature in the commonly-described ‘Adoption Triangle’1 of birth parent, child and prospective adopters. Social workers construct care plans, making recommenda... Read More about Squaring the Adoption Triangle: reconciling the competing needs of sibling children.

Deep Reinforcement Learning for Smart Energy Networks (2023)
Thesis

To reduce global greenhouse gas emissions, the world must find intelligent solutions to maximise the utilisation of carbon-free renewable energy sources (RES). Energy storage systems (ESS) can be used to store energy when RES generation exceeds deman... Read More about Deep Reinforcement Learning for Smart Energy Networks.

Alzheimer's Disease: Investigating the neuroprotective role of Polyunsaturated fatty acids against β-Amyloid accumulation using SH-SY5Y cell models (2023)
Thesis

Alzheimer’s disease is the most common type of dementia characterised by cognitive impairments such as memory loss as well as behavioural symptoms like depression and aggression. The hallmark of the disease is the accumulation of beta-Amyloid (Aβ) as... Read More about Alzheimer's Disease: Investigating the neuroprotective role of Polyunsaturated fatty acids against β-Amyloid accumulation using SH-SY5Y cell models.

Mystical Post-anarchism (2023)
Thesis

The aim of this thesis is to explore the theoretical response that a mystical approach to post-anarchism can provide to the problems of domination and control within the contemporary capitalist state. In doing this, it also seeks to find a way past s... Read More about Mystical Post-anarchism.

Music and sound in the Japanese 'ghost' film: cultural representation and transformation (2023)
Thesis

This thesis examines the role of music and sound in Japanese ‘ghost’ films. Scholarship on contemporary Japanese horror cinema often examines culture-bound descriptions of spirits. Such discussion typically revolves around tensions between, on the on... Read More about Music and sound in the Japanese 'ghost' film: cultural representation and transformation.

In-solution and interface study on biological model membranes and their interaction with Prohibitin (2023)
Thesis

Prohibitins (PHB) play a crucial role in premature cellular ageing, tumour suppression, cell cycle regulation, and apoptosis, and their deregulation is involved in viral infections, neurological and cardiovascular diseases and cancer. Despite the ess... Read More about In-solution and interface study on biological model membranes and their interaction with Prohibitin.

The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin (2023)
Thesis

The following thesis began by discussing current controversies surrounding EPC identification then studied the effect of atorvastatin on EPC numbers in bench and bed side studies. Atorvastatin was hypothesised to increase chemokine CXCL-12 its recep... Read More about The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin.