All Outputs (1721)

ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control (2023)
Thesis
Devlin, A. J. ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518613

Heparin is a member of the glycosaminoglycan (GAG) family of naturally occurring, polydisperse, linear polysaccharides. Heparin is a ubiquitous anticoagulant drug, a member of the WHO’s list of vital medicines and the second used drug by weight after... Read More about ATR-FTIR spectroscopy of heparin: using multivariate analyses for next-generation quality control.

The effect of construct configuration on the mechanical stiffness and strength of spinal implants for kyphotic spinal deformity (2023)
Thesis
Tsang, K. S. The effect of construct configuration on the mechanical stiffness and strength of spinal implants for kyphotic spinal deformity. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518875

Spinal deformity involves a wide spectrum of disease, including congenital, developmental, degenerative and traumatic; affecting infant, adolescence and the elderly. Of these, Sheuermann’s kyphosis is a form of developmental long spinal deformity, ch... Read More about The effect of construct configuration on the mechanical stiffness and strength of spinal implants for kyphotic spinal deformity.

Statistical methods for prognostic factor and risk prediction research (2023)
Thesis
Whittle, R. L. Statistical methods for prognostic factor and risk prediction research. (Thesis). Keele University. https://keele-repository.worktribe.com/output/515791

Prognosis research is an important part of medical research as it seeks to understand, predict, and improve future outcomes in people with a given disease or health condition. This thesis focuses on the application and development of statistical meth... Read More about Statistical methods for prognostic factor and risk prediction research.

Fundamental parameters of very low mass stars in eclipsing binary star systems observed with the CHEOPS satellite (2023)
Thesis
Swayne, M. I. Fundamental parameters of very low mass stars in eclipsing binary star systems observed with the CHEOPS satellite. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518842

Observations of low-mass stars have frequently shown unexpectedly large stellar radii when compared to the predictions from theoretical stellar structure models. This “radius inflation” problem may have consequences not just for stellar science but a... Read More about Fundamental parameters of very low mass stars in eclipsing binary star systems observed with the CHEOPS satellite.

Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate (2023)
Thesis
Brown-Lyons, A. L. Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518848

Background: Inflammation is a major driver, and perhaps cause, of neurodegeneration, suggesting neuroimmunomodulation as a therapeutic strategy. Microglia, the primary mediators of neuroinflammation, switch between three activation states [surveillan... Read More about Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate.

Between pragmatism and ideology: role-conflict management in Turkey’s foreign policy towards Israel under the Adalet ve Kalkınma Partisi (AKP), 2002-2022 (2023)
Thesis
Çelik, A. Between pragmatism and ideology: role-conflict management in Turkey’s foreign policy towards Israel under the Adalet ve Kalkınma Partisi (AKP), 2002-2022. (Thesis). Keele University. https://keele-repository.worktribe.com/output/522414

The opposed tendencies in Turkey’s foreign policy—shifting between pragmatism and ideology—have become an issue of debate in both political and academic circles ever since the Adalet ve Kalkınma Partisi (Justice and Development Party, or AKP) came to... Read More about Between pragmatism and ideology: role-conflict management in Turkey’s foreign policy towards Israel under the Adalet ve Kalkınma Partisi (AKP), 2002-2022.

Radio and infrared surveys for active galactic nuclei behind the Magellanic Clouds (2023)
Thesis
Pennock, C. M. Radio and infrared surveys for active galactic nuclei behind the Magellanic Clouds. (Thesis). Keele University. https://keele-repository.worktribe.com/output/515724

I present an analysis of a new 120 deg2 radio continuum image of the Large Magellanic Cloud (LMC) at 888 MHz with a bandwidth of 288 MHz and beam size of 13.′′9×12.′′1, from the Australian Square Kilometre Array Pathfinder (ASKAP). I constructed a ca... Read More about Radio and infrared surveys for active galactic nuclei behind the Magellanic Clouds.

The evaluation of a metabonomic approach to detect decomposition products in water and leachates using Liquid Chromatography-Mass Spectrometry (2023)
Thesis
Williams, M. F. The evaluation of a metabonomic approach to detect decomposition products in water and leachates using Liquid Chromatography-Mass Spectrometry. (Thesis). Keele University. https://keele-repository.worktribe.com/output/515544

Statistics show that there was a 12% increase in missing persons’ incidents in the UK between 2014 and 2019. Approximately 50% of these missing individuals are found within 24 hours, and on average a large number will be deceased. Land-based searches... Read More about The evaluation of a metabonomic approach to detect decomposition products in water and leachates using Liquid Chromatography-Mass Spectrometry.

Conscious robots: what happens when a philosophical confusion becomes a societal reality? (2023)
Thesis
Ozdemir, S. Conscious robots: what happens when a philosophical confusion becomes a societal reality?. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518830

This thesis is an investigation into philosophical issues surrounding the production of human-like robots. I will argue that there is no reason to think conscious robots will ever be built, but that supposedly conscious robots that are able to emulat... Read More about Conscious robots: what happens when a philosophical confusion becomes a societal reality?.

Deciphering the atmospheric properties of hot gas giant exoplanets via ground-based transmission spectroscopy (2023)
Thesis
Spyratos, P. Deciphering the atmospheric properties of hot gas giant exoplanets via ground-based transmission spectroscopy. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518836

Transiting hot gas giant exoplanets are great targets for atmospheric investigations due to their extended atmospheres and their strong obscuring effect on the observed starlight when they pass in front of their host star. Transmission spectroscopy c... Read More about Deciphering the atmospheric properties of hot gas giant exoplanets via ground-based transmission spectroscopy.

The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin (2023)
Thesis
Sandhu, K. S. The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518404

The following thesis began by discussing current controversies surrounding EPC identification then studied the effect of atorvastatin on EPC numbers in bench and bed side studies.
Atorvastatin was hypothesised to increase chemokine CXCL-12 its recep... Read More about The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin.

“Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status (2023)
Thesis
Machin, H. E. “Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518045

Undocumented Chinese migration to the UK has, in the aftermath of widely publicised events such as the Dover and Morecambe Bay tragedies, triggered significant concern. Since such events, attention has turned to other forms of irregular entry. Yet, u... Read More about “Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status.

Understanding process of management control changes in hybrid organisational contracts (2023)
Thesis
Zaidi, U. Understanding process of management control changes in hybrid organisational contracts. (Thesis). Keele University. https://keele-repository.worktribe.com/output/517966

Motivated by controversial public and private sector hybrid organisational relationships and, more broadly, by repeated calls regarding control and management of hybrid organisational relationships, this thesis is concerned with the understanding pro... Read More about Understanding process of management control changes in hybrid organisational contracts.

Chemical synthesis of fluorinated carbocyclic nucleoside analogues (2023)
Thesis
Benckendorff, C. M. M. Chemical synthesis of fluorinated carbocyclic nucleoside analogues. (Thesis). Keele University. https://keele-repository.worktribe.com/output/529473

Since the discovery of their pharmaceutical potential, nucleoside analogues have become one of the most important classes of chemotherapeutic agents in the treatment of many cancers and viral infections. In many chronic illnesses, such as HBV or HIV... Read More about Chemical synthesis of fluorinated carbocyclic nucleoside analogues.

Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay (2023)
Thesis
Freakley, A. L. Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518051

Leishmaniasis is a neglected tropical disease associated with poverty, deprived socio-economic settings and population displacement, primarily due to conflict. The causative agent are species of Leishmania parasites that are transmitted by sand flies... Read More about Study to determine the rate of kill of anti-leishmanial drugs using a novel bioluminescence-based assay.

The management of varices in acute on chronic liver failure: a systematic review of guidelines and investigation of local practice (2023)
Thesis
Kesavan, S. The management of varices in acute on chronic liver failure: a systematic review of guidelines and investigation of local practice. (Thesis). Keele University. https://keele-repository.worktribe.com/output/515604

Varices are a complication of chronic liver disease and are associated with a high mortality if they haemorrhage. Patients need to be managed using the best available evidence to improve their outcomes. This thesis is formed of two parts: a systemati... Read More about The management of varices in acute on chronic liver failure: a systematic review of guidelines and investigation of local practice.

Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study (2023)
Thesis
Campbell, L. H. Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518227

Background - First Contact Physiotherapists (FCPs) specialise in supporting people who consult with musculoskeletal conditions in National Health Service primary care. Cited FCP role challenges include professional isolation, time demands and changin... Read More about Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study.

UAVS as a platform for earthwork heritage: monitoring, documentation and visualisation (2023)
Thesis
Malbon, H. UAVS as a platform for earthwork heritage: monitoring, documentation and visualisation. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518455

Conservation of Cultural Heritage has been a mainstay of UNESCO and other such organisations for decades, whether it is artefacts, buildings, or earthworks. With the increase of tourism, urban encroachment, climate change, or naturally occurring proc... Read More about UAVS as a platform for earthwork heritage: monitoring, documentation and visualisation.

Gender mainstreaming in Sri Lanka, 1978-2015 (2023)
Thesis
Hettiarachchi, S. H. Gender mainstreaming in Sri Lanka, 1978-2015. (Thesis). Keele University. https://keele-repository.worktribe.com/output/515774

Gender mainstreaming has been the most “modern” policy approach to gender equality, over the globe. It is also served as a policy strategy to ensure equality for women in society. Sri Lanka is seriously pondering into uplifting gender mainstreaming s... Read More about Gender mainstreaming in Sri Lanka, 1978-2015.

A social realist challenge to the structuring of professional practice knowledge for initial teacher education in England (2023)
Thesis
Swift, D. A social realist challenge to the structuring of professional practice knowledge for initial teacher education in England. (Thesis). Keele University. https://keele-repository.worktribe.com/output/518059

Professional practice knowledge for beginning teachers involves grappling with the extent to which ‘theory’ and ‘practice’ should be evident during initial teacher education courses. The end point assessment tool for such programmes in England is tha... Read More about A social realist challenge to the structuring of professional practice knowledge for initial teacher education in England.