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All Outputs (1651)

Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity (2022)
Thesis
Sargeant, K. E. (2022). Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity. (Thesis). Keele University

Background: Greater understanding of NQNs’ perceptions of their pre-registration and transition experiences, and influences on their perceptions can inform pre-registration curricula and preceptorship programmes to support a positive transition to qu... Read More about Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity.

An in vitro study of the modulation of astrocytes in the blood brain barrier during human cerebral malaria (2022)
Thesis
Ogbolosingha, A. J. (2022). An in vitro study of the modulation of astrocytes in the blood brain barrier during human cerebral malaria. (Thesis). Keele University

Cerebral malaria (CM) is the most life-threatening complication of Plasmodium falciparum (Pf) infection. A key hallmark of CM is the sequestration of Pf infected red blood cells (PRBC) to the human brain endothelial cells (HBEC) of the blood brain ba... Read More about An in vitro study of the modulation of astrocytes in the blood brain barrier during human cerebral malaria.

Exploring the use of attractive sugar bait stations to deliver antiplasmodial compounds to Anopheles mosquitoes (2022)
Thesis
Highton, G. A. (2022). Exploring the use of attractive sugar bait stations to deliver antiplasmodial compounds to Anopheles mosquitoes. (Thesis). Keele University

Between 2000 and 2015, Sub-Saharan Africa made historic process against the scourge of malaria. Since this time there has been a plateau in the number of malaria cases and mortalities. The decreasing efficacy of the current methods used against this... Read More about Exploring the use of attractive sugar bait stations to deliver antiplasmodial compounds to Anopheles mosquitoes.

Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke (2022)
Thesis
Singh, A. (2022). Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke. (Thesis). Keele University

Ischaemic stroke is the most common form of stroke, accounting for appropriate 87% of all strokes. Reperfusion is the only immediate treatment option following ischaemic stroke, however, this option is only applicable to a small percentage of patient... Read More about Activation of Hypoxia Inducible Factor pathway for neuroprotection in in vitro models of ischaemic stroke.

Neuroevolution of bipedal locomotion: algorithmic, balance penalty and morphological improvements for improved robustness and performance (2022)
Thesis
Jackson, B. (2022). Neuroevolution of bipedal locomotion: algorithmic, balance penalty and morphological improvements for improved robustness and performance. (Thesis). Keele University

Bipedalism is theorised to have emerged in humans in order to enable endurance running and tool use via the hands. It is one of the most complex styles of locomotion, with agents typically having a high center of mass and two feet very close together... Read More about Neuroevolution of bipedal locomotion: algorithmic, balance penalty and morphological improvements for improved robustness and performance.

Radical idealism and empirical metaphysics in the work of Mary Baker Eddy (2022)
Thesis
Sheldon, N. D. (2022). Radical idealism and empirical metaphysics in the work of Mary Baker Eddy. (Thesis). Keele University

The nineteenth-century American, Mary Baker Eddy, is well known in the United States for having founded the religion Christian Science, but she is not generally regarded as philosopher, let alone an original one. This dissertation argues that she is... Read More about Radical idealism and empirical metaphysics in the work of Mary Baker Eddy.

A multimodal approach to biomarker discovery for spinal cord injury (2022)
Thesis
Bernardo Harrington, G. M. (2022). A multimodal approach to biomarker discovery for spinal cord injury. (Thesis). Keele University

The extent of the devastating outcomes following spinal cord injury, particularly with respect to neurological function, are difficult to predict. This can make it difficult to plan clinical care and manage patient expectations, both of which can hav... Read More about A multimodal approach to biomarker discovery for spinal cord injury.

User-centred design of bedside clinical guidelines for mobile devices (2022)
Thesis
Mitchell, J. A. (2022). User-centred design of bedside clinical guidelines for mobile devices. (Thesis). Keele University

Local point of care clinical guidelines exist in numerous formats and cover a variety of clinical information, normally created on a national and local level. They are generally available as basic web pages, PDFs or documents. Despite widespread avai... Read More about User-centred design of bedside clinical guidelines for mobile devices.

The influence of halokinesis on shallow-marine sediments in salt basins: The Fulmar Formation, Central North Sea, UK (2022)
Thesis
Foey, J. A. L. (2022). The influence of halokinesis on shallow-marine sediments in salt basins: The Fulmar Formation, Central North Sea, UK. (Thesis). Keele University

Salt collapse structures host significant hydrocarbon reserves and have enormous economic importance, however despite this there is comparatively little research conducted on their evolution, structure and facies distribution. This thesis provides an... Read More about The influence of halokinesis on shallow-marine sediments in salt basins: The Fulmar Formation, Central North Sea, UK.

Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records (2022)
Thesis
Dyer, B. P. (2022). Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records. (Thesis). Keele University

Introduction
Frozen shoulder, a condition that can cause prolonged pain and disability, has previously been found to be common amongst people with diabetes. This thesis aimed to improve the understanding of the nature of the relationship between dia... Read More about Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records.

Contesting piety: representations of Indonesian internet celebrities on Instagram (2022)
Thesis
Annisa, F. (2022). Contesting piety: representations of Indonesian internet celebrities on Instagram. (Thesis). Keele University

This thesis aims to ascertain how, through the social media platform Instagram, Muslim women internet celebrities represent themselves as public figures who can represent the ummah. Through their self-representation on social media, Muslim women inte... Read More about Contesting piety: representations of Indonesian internet celebrities on Instagram.

An in vitro study into the effects of erastin in the SH-SY5Y cell line, as a model of Parkinson’s disease (2022)
Thesis
Earle, H. (2022). An in vitro study into the effects of erastin in the SH-SY5Y cell line, as a model of Parkinson’s disease. (Thesis). Keele University

Ferroptosis is a non-apoptotic, iron-dependent cell death pathway first identified in an engineered tumorigenic cell line in 2012. Hallmark characteristics include direct or indirect loss of functional GPX4 enzymes, resulting in depletion of glutathi... Read More about An in vitro study into the effects of erastin in the SH-SY5Y cell line, as a model of Parkinson’s disease.

Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis (2022)
Thesis
Burgess, R. M. (2022). Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis. (Thesis). Keele University

Introduction: High quality data on service performance is essential in healthcare. There is however a paucity of publicly reported data in community/primary care musculoskeletal (MSK) services. There is also a lack of guidance on which metrics servic... Read More about Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis.

From quarks to cognition: in pursuit of a complete micropsychist theory of consciousness (2022)
Thesis
Hibbert, B. J. (2022). From quarks to cognition: in pursuit of a complete micropsychist theory of consciousness. (Thesis). Keele University

Despite having received a recent resurgence of interest, Panpsychism remains a worldview afflicted by various explanatory shortfalls. Chiefly, the literature is yet to provide a ‘proper’ panpsychist theory of consciousness with the potential to expla... Read More about From quarks to cognition: in pursuit of a complete micropsychist theory of consciousness.

Impulsive-compulsive behaviours in Parkinson’s disease: a behavioural, neuroimaging and neurophysiological investigation (2022)
Thesis
Martini, A. (2022). Impulsive-compulsive behaviours in Parkinson’s disease: a behavioural, neuroimaging and neurophysiological investigation. (Thesis). Keele University

Background: Persons with Parkinson’s (PwP) may develop Impulsivecompulsive behaviours (ICBs) as side-effect of dopamine replacement therapy (DRT). The unresolved question addressed by this thesis is why only some PwP develop ICBs. This is an importan... Read More about Impulsive-compulsive behaviours in Parkinson’s disease: a behavioural, neuroimaging and neurophysiological investigation.

Military logistics and supply during the British Civil Wars, 1638–1653 (2022)
Thesis
Price, G. W. (2022). Military logistics and supply during the British Civil Wars, 1638–1653. (Thesis). Keele University

The aim of this thesis is to analyse the logistics and supply systems of the armies during the British Civil Wars at an operational level. Current historical works have neglected to fully evaluate the events of the British Civil Wars with respect to... Read More about Military logistics and supply during the British Civil Wars, 1638–1653.

Examining the self-representation of hijab fashion bloggers as a postfeminist phenomenon: discourses of empowerment and their limitations (2022)
Thesis
Mora, L. (2022). Examining the self-representation of hijab fashion bloggers as a postfeminist phenomenon: discourses of empowerment and their limitations. (Thesis). Keele University

In the last decade, hijab fashion bloggers on Instagram have gained remarkable levels of popularity among young Muslim women. While scholars have recognised the importance of describing and celebrating the empowering sides of hijab fashion as a subcu... Read More about Examining the self-representation of hijab fashion bloggers as a postfeminist phenomenon: discourses of empowerment and their limitations.

Cell models to evaluate oligodendrocyte lineage cell growth on biomaterials (2022)
Thesis
Chowdhury, F. (2022). Cell models to evaluate oligodendrocyte lineage cell growth on biomaterials. (Thesis). Keele University

Oligodendrocyte lineage and neuronal cells are essential neural populations required for axonal remyelination after spinal cord injury (SCI). Injection of an exogenous cell population into the site of neural injury has posed translational barriers, s... Read More about Cell models to evaluate oligodendrocyte lineage cell growth on biomaterials.