Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis

Ishigaki, Kazuyoshi; Sakaue, Saori; Terao, Chikashi; Luo, Yang; Sonehara, Kyuto; Yamaguchi, Kensuke; Amariuta, Tiffany; Lai Too, Chun; A Laufer, Vincent; C Scott, Ian; Viatte, Sebastien; Takahashi, Meiko; Ohmura, Koichiro; Murasawa, Akira; Hashimoto, Motomu; Ito, Hiromu; Hammoudeh, Mohammed; Al Emadi, Samar; K Masri, Basel; Halabi, Hussien; Badsha, Humeria; W Uthman, Imad; Wu, Xin; Lin, Li; Lin, Ting; Plant, Darren; Barton, Anne; Orozco, Gisela; MM Verstappen, Suzanne; Bowes, John; J MacGregor, Alexander; Honda, Suguru; Koido, Masaru; Tomizuka, Kohei; Kamatani, Yoichiro; Tanaka, Hiroaki; Tanaka, Eiichi; Suzuki, Akari; Maeda, Yuichi; Yamamoto, Kenichi; Miyawaki, Satoru; Xie, Gang; Zhang, Jinyi; Amos, Chris; Keystone, Ed; Wolbink, Gertjan; van der Horst-Bruinsma, Irene; Cui, Jing; P Liao, Katherine; J Carroll, Robert

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Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis (2021)
Working Paper
Ishigaki, K., Sakaue, S., Terao, C., Luo, Y., Sonehara, K., Yamaguchi, K., …J Carroll, R. Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis

Trans-ancestry genetic research promises to improve power to detect genetic signals, fine-mapping resolution, and performances of polygenic risk score (PRS). We here present a large-scale genome-wide association study (GWAS) of rheumatoid arthritis (... Read More about Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis.