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Synthesis and Scalable Conversion of l-Iduronamides to Heparin-Related Di- and Tetrasaccharides (2012)
Journal Article
Miller. (2012). Synthesis and Scalable Conversion of l-Iduronamides to Heparin-Related Di- and Tetrasaccharides. Journal of Organic Chemistry, 7823 -7843. https://doi.org/10.1021/jo300722y

A diastereomerically pure cyanohydrin, preparable on kilogram scale, is efficiently converted in one step into a novel l-iduronamide. A new regioselective acylation of this iduronamide and a new mild amide hydrolysis method mediated by amyl nitrite e... Read More about Synthesis and Scalable Conversion of l-Iduronamides to Heparin-Related Di- and Tetrasaccharides.

Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine. (2012)
Journal Article
Richardson, A., Stamelos, V., & Redman, C. (2012). Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine. Journal of Molecular Signaling, 12 - ?. https://doi.org/10.1186/1750-2187-7-12

BH3 mimetics such as ABT-737 and navitoclax bind to the BCL-2 family of proteins and induce apoptosis through the intrinsic apoptosis pathway. There is considerable variability in the sensitivity of different cells to these drugs. Understanding the m... Read More about Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine..

Surveillance technologies and the crises of confidence in regulatory agencies (2012)
Journal Article
Kearon, T. (2013). Surveillance technologies and the crises of confidence in regulatory agencies. Criminology and Criminal Justice, 13(4), 415-430. https://doi.org/10.1177/1748895812454747

Technology plays an increasing role in policing and other aspects of the criminal justice process. This article will briefly outline the notion of a criminal justice ‘techno-fix’ as a potential attempt by criminal justice agencies to use technology a... Read More about Surveillance technologies and the crises of confidence in regulatory agencies.

Does life course socio-economic position influence chronic disabling pain in older adults? A general population study (2012)
Journal Article
Lacey, R. J., Belcher, J., & Croft, P. R. (2013). Does life course socio-economic position influence chronic disabling pain in older adults? A general population study. European Journal of Public Health, 23(4), 534 - 540. https://doi.org/10.1093/eurpub/cks056

Background
Chronic pain is the leading cause of disability in developed countries. Prevalence is linked with socio-economic position (SEP), but little is known about the influence of SEP on disabling pain over the life course. We have investigated t... Read More about Does life course socio-economic position influence chronic disabling pain in older adults? A general population study.

Stalag Luft III: The Archaeology of an Escaper’s Camp (2012)
Book Chapter
Doyle, P., Pringle, J., & Babits, L. E. (2013). Stalag Luft III: The Archaeology of an Escaper’s Camp. In Prisoners of War (129-144). Springer New York. https://doi.org/10.1007/978-1-4614-4166-3_8

Stalag Luft III was a German prisoner of war camp for Allied aviators during World War II. Situated at Zagan, Poland, in what was once eastern Germany, the site is famous for repeated escape attempts, particularly the mass escape of 79 PoWs in March... Read More about Stalag Luft III: The Archaeology of an Escaper’s Camp.

EChO - Exoplanet Characterisation Observatory (2012)
Journal Article
Tinetti, G., Beaulieu, J., Henning, T., Meyer, M., Micela, G., Ribas, I., …Yurchenko, S. (2012). EChO - Exoplanet Characterisation Observatory. Experimental Astronomy, 34, 311-353. https://doi.org/10.1007/s10686-012-9303-4

A dedicated mission to investigate exoplanetary atmospheres represents a major milestone in our quest to understand our place in the universe by placing our Solar System in context and by addressing the suitability of planets for the presence of life... Read More about EChO - Exoplanet Characterisation Observatory.

Parasites, proteomes and systems: has Descartes' clock run out of time? (2012)
Journal Article
(2012). Parasites, proteomes and systems: has Descartes' clock run out of time?. Parasitology, 1103 - 1118. https://doi.org/10.1017/S0031182012000716

Systems biology aims to integrate multiple biological data types such as genomics, transcriptomics and proteomics across different levels of structure and scale; it represents an emerging paradigm in the scientific process which challenges the reduct... Read More about Parasites, proteomes and systems: has Descartes' clock run out of time?.

Three empirical studies on the agreement of reviewers about the quality of software engineering experiments (2012)
Journal Article
(2012). Three empirical studies on the agreement of reviewers about the quality of software engineering experiments. Information and Software Technology, 804 -819. https://doi.org/10.1016/j.infsof.2011.11.008

Context
During systematic literature reviews it is necessary to assess the quality of empirical papers. Current guidelines suggest that two researchers should independently apply a quality checklist and any disagreements must be resolved. However, t... Read More about Three empirical studies on the agreement of reviewers about the quality of software engineering experiments.

HSTEP -- Homogeneous Studies of Transiting Extrasolar Planets (2012)
Conference Proceeding
Southworth, J. (2012). HSTEP -- Homogeneous Studies of Transiting Extrasolar Planets. . https://doi.org/10.1017/S174392131301332X

I give a summary of the HSTEP project: an effort to calculate the physical properties of the known transiting extrasolar planets using a homogeneous approach. I discuss the motivation for the project, list the 83 planets which have already been studi... Read More about HSTEP -- Homogeneous Studies of Transiting Extrasolar Planets.

Investigating the significance of dissolved organic contaminants in aquatic environments: Coupling passive sampling with in vitro bioassays (2012)
Journal Article
Emelogu, E. S., Pollard, P., Robinson, C. D., Smedes, F., Webster, L., Oliver, I. W., …Moffat, C. F. (2013). Investigating the significance of dissolved organic contaminants in aquatic environments: Coupling passive sampling with in vitro bioassays. Chemosphere, 90(2), 210-219. https://doi.org/10.1016/j.chemosphere.2012.06.041

We investigated the feasibility of coupling passive sampling and in vitro bioassay techniques for both chemical and ecotoxicological assessment of complex mixtures of organic contaminants in water. Silicone rubber passive sampling devices (SR-PSDs) w... Read More about Investigating the significance of dissolved organic contaminants in aquatic environments: Coupling passive sampling with in vitro bioassays.

Capturing Browsing Interests of Users into Web Usage Profiles (2012)
Presentation / Conference
Kabir, S., Mudur, S., & Shiri, N. (2012, July). Capturing Browsing Interests of Users into Web Usage Profiles. Presented at 26th AAAI Conference on Artificial Intelligence (AAAI-12), Toronto, Ontario, Canada

We present a new weighted session similarity measure to capture the browsing interests of users in web usage profiles discovered from web log data. We base our similarity measure on the reasonable assumption that when users spend longer times on page... Read More about Capturing Browsing Interests of Users into Web Usage Profiles.

Biocompatibility and Toxicity of Magnetic Nanoparticles in Regenerative Medicine (2012)
Journal Article
(2012). Biocompatibility and Toxicity of Magnetic Nanoparticles in Regenerative Medicine. Journal of Nanomaterials, https://doi.org/10.1155/2012/614094

Regenerative medicine is a pioneering field aimed at restoring and regenerating the function of damaged cells, organs and tissues in order to establish normal function. It demands the cross communication of disciplines to develop effective therapeuti... Read More about Biocompatibility and Toxicity of Magnetic Nanoparticles in Regenerative Medicine.

Club cells inhibit alveolar epithelial wound repairviaTRAIL-dependent apoptosis (2012)
Journal Article
Akram, K. M., Lomas, N. J., Spiteri, M. A., & Forsyth, N. R. (2013). Club cells inhibit alveolar epithelial wound repairviaTRAIL-dependent apoptosis. European Respiratory Journal, 41(3), 683-694. https://doi.org/10.1183/09031936.00213411

Club cells (Clara cells) participate in bronchiolar wound repair and regeneration. Located in the bronchioles, they become activated during alveolar injury in idiopathic pulmonary fibrosis (IPF) and migrate into the affected alveoli, a process called... Read More about Club cells inhibit alveolar epithelial wound repairviaTRAIL-dependent apoptosis.