Skip to main content

Research Repository

Advanced Search

All Outputs (1441)

Anne Conway on Time, the Trinity and Eschatology (2017)
Journal Article
Head. (2017). Anne Conway on Time, the Trinity and Eschatology. Philosophy and Theology, 277-295. https://doi.org/10.5840/philtheol201781480

This paper considers the conception of the Triune God, soteriology and eschatology in Anne Conway’s metaphysics. After outlining some of the key features of her thought, including her account of a timeless God who is nevertheless intimately present i... Read More about Anne Conway on Time, the Trinity and Eschatology.

Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis (2017)
Journal Article
(2017). Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis. Annals of the Rheumatic Diseases, 1774-1779. https://doi.org/10.1136/annrheumdis-2017-211414

Objectives Psoriatic arthritis (PsA) is a chronic inflammatory arthritis, with a strong heritable component, affecting patients with psoriasis. Here we attempt to identify genetic variants within the major histocompatibility complex (MHC) that differ... Read More about Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis.

Aluminum Exposure for 60 days at Human Dietary Levels Impairs Spermatogenesis and Sperm Quality in Rats (2017)
Journal Article
(2017). Aluminum Exposure for 60 days at Human Dietary Levels Impairs Spermatogenesis and Sperm Quality in Rats. Reproductive Toxicology, 128-141. https://doi.org/10.1016/j.reprotox.2017.08.008

Abstract Concerns about environmental aluminum (Al) and reproductive health have been raised. We investigated the effects of Al exposure at a human relevant dietary level and a high level exposure to Al. Experiment 1 (Lower level) rats were treated o... Read More about Aluminum Exposure for 60 days at Human Dietary Levels Impairs Spermatogenesis and Sperm Quality in Rats.

A Systematic Mapping Study of Empirical Studies on Software Cloud Testing Methods (2017)
Conference Proceeding
Al-Said Ahmad, A., Brereton, O., & Andras, P. (2017). A Systematic Mapping Study of Empirical Studies on Software Cloud Testing Methods. In 2017 IEEE International Conference on Software Quality, Reliability and Security Companion (QRS-C). https://doi.org/10.1109/QRS-C.2017.94

Context: Software has become more complicated, dynamic, and asynchronous than ever, making testing more challenging. With the increasing interest in the development of cloud computing, and increasing demand for cloud-based services, it has become ess... Read More about A Systematic Mapping Study of Empirical Studies on Software Cloud Testing Methods.

Autonomous magnetic labelling of functional mesenchymal stem cells for improved traceability and spacial control in cell therapy applications (2017)
Journal Article
(2017). Autonomous magnetic labelling of functional mesenchymal stem cells for improved traceability and spacial control in cell therapy applications. Journal of Tissue Engineering and Regenerative Medicine, 2333-2348. https://doi.org/10.1002/term.2133

Mesenchymal stem cells (MSCs) represent a valuable resource for regenerative medicine treatments for orthopaedic repair and beyond. Following developments in isolation, expansion and differentiation protocols, efforts to promote clinical translation... Read More about Autonomous magnetic labelling of functional mesenchymal stem cells for improved traceability and spacial control in cell therapy applications.

Migratory Eurasian Reed Warblers Can Use Magnetic Declination to Solve the Longitude Problem. (2017)
Journal Article
Chernetsov, N., Pakhomov, A., Kobylkov, D., Kishkinev, D., Holland, R. A., & Mouritsen, H. (2017). Migratory Eurasian Reed Warblers Can Use Magnetic Declination to Solve the Longitude Problem. Current Biology, 2647 - 2651.e2. https://doi.org/10.1016/j.cub.2017.07.024

The longitude problem (determining east-west position) is a classical problem in human sea navigation. Prior to the use of GPS satellites, extraordinarily accurate clocks measuring the difference between local time and a fixed reference (e.g., GMT) [... Read More about Migratory Eurasian Reed Warblers Can Use Magnetic Declination to Solve the Longitude Problem..

Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations (2017)
Journal Article
(2017). Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations. PloS one, 1 -17. https://doi.org/10.1371/journal.pone.0183358

Introduction Vitamin B3 has been shown to play an important role during embryogenesis. Specifically, there is growing evidence that nicotinamide, the biologically active form of vitamin B3, plays a critical role as a morphogen in the differentiation... Read More about Nicotinamide alone accelerates the conversion of mouse embryonic stem cells into mature neuronal populations.

Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle (2017)
Journal Article
Fisher, A. G., Seaborne, R. A., Hughes, T. M., Gutteridge, A., Stewart, C., Coulson, J. M., …Jarvis, J. C. (2017). Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle. FASEB Journal, 31(12), 5268-5282. https://doi.org/10.1096/fj.201700089RR

Physical inactivity and disuse are major contributors to age-related muscle loss. Denervation of skeletal muscle has been previously used as a model with which to investigate muscle atrophy following disuse. Although gene regulatory networks that con... Read More about Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle.

Final year physiotherapy student's reliability in chest x-ray interpretation (2017)
Journal Article
(2017). Final year physiotherapy student's reliability in chest x-ray interpretation. Physiotherapy Theory and Practice, 54-57. https://doi.org/10.1080/09593985.2017.1360423

Background: Newly qualified physiotherapists may be required to interpret an unreported chest X-ray (CXR) as part of their physiotherapy assessment in “on call” situations. Their interpretation may influence the patient management strategies they ado... Read More about Final year physiotherapy student's reliability in chest x-ray interpretation.

Evidence for a radiatively driven disc-wind in PDS 456? (2017)
Journal Article
(2017). Evidence for a radiatively driven disc-wind in PDS 456?. Monthly Notices of the Royal Astronomical Society: Letters, L15-L19. https://doi.org/10.1093/mnrasl/slx129

We present a newly discovered correlation between the wind outflow velocity and the X-ray luminosity in the luminous ($L_{\rm bol}\sim10^{47}\,\rm erg\,s^{-1}$) nearby ($z=0.184$) quasar PDS\,456. All the contemporary XMM-Newton, NuSTAR and Suzaku ob... Read More about Evidence for a radiatively driven disc-wind in PDS 456?.

Microclimatic temperatures increase the potential for vector-borne disease transmission in the Scandinavian climate (2017)
Journal Article
Haider, N., Kirkeby, C., Kristensen, B., Jung Kjær, L., Havskov Sørensen, J., & Bødker, R. (2017). Microclimatic temperatures increase the potential for vector-borne disease transmission in the Scandinavian climate. Scientific reports, https://doi.org/10.1038/s41598-017-08514-9

We quantified the difference between the meteorological temperature recorded by the Danish Meteorological Institute (DMI) weather stations and the actual microclimatic temperatures at two or three different heights at six potential insect habitats. W... Read More about Microclimatic temperatures increase the potential for vector-borne disease transmission in the Scandinavian climate.

The implementation of long-lasting insecticidal bed nets has differential effects on the genetic structure of the African malaria vectors in the Anopheles gambiae complex in Dielmo, Senegal. (2017)
Journal Article
(2017). The implementation of long-lasting insecticidal bed nets has differential effects on the genetic structure of the African malaria vectors in the Anopheles gambiae complex in Dielmo, Senegal. Malaria Journal, 337 - ?. https://doi.org/10.1186/s12936-017-1992-8

BACKGROUND: Mosquitoes belonging to the Anopheles gambiae complex are the main vectors of malaria in sub-Saharan Africa. Among these, An. gambiae, Anopheles coluzzii and Anopheles arabiensis are the most efficient vectors and are largely distributed... Read More about The implementation of long-lasting insecticidal bed nets has differential effects on the genetic structure of the African malaria vectors in the Anopheles gambiae complex in Dielmo, Senegal..

Management of Acute Stroke in the Older Person. (2017)
Journal Article
Parr, E., Ferdinand, P., & Roffe, C. (2017). Management of Acute Stroke in the Older Person. Geriatrics, 2(3), Article 27. https://doi.org/10.3390/geriatrics2030027

The majority of people who suffer a stroke are older adults. The last two decades have brought major progress in the diagnosis and management of stroke, which has led to significant reductions in mortality, long-term disability, and the need for inst... Read More about Management of Acute Stroke in the Older Person..

mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review (2017)
Journal Article
Gire, N., Farooq, S., Naeem, F., Duxbury, J., McKeown, M., Kundi, P. S., …Husain, N. mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review. mHealth, 3, 33-33. https://doi.org/10.21037/mhealth.2017.07.03

The relative burden of mental health disorders is increasing globally, in terms of prevalence and disability. There is limited data available to guide treatment choices for clinicians in low resourced settings, with mHealth technologies being a poten... Read More about mHealth based interventions for the assessment and treatment of psychotic disorders: a systematic review.

A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects. (2017)
Journal Article
(2017). A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects. Biometrics, 548 - 556. https://doi.org/10.1111/biom.12762

Random-effects meta-analyses are very commonly used in medical statistics. Recent methodological developments include multivariate (multiple outcomes) and network (multiple treatments) meta-analysis. Here, we provide a new model and corresponding est... Read More about A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects..

Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells (2017)
Journal Article
Abed, M., Richardson, A., & Abdullah, M. (2017). Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells. Scientific reports, 8090 -?. https://doi.org/10.1038/s41598-017-08649-9

Only 40% of patients with advanced ovarian cancer survive more than 5 years. We have previously shown that pitavastatin induces regression of ovarian cancer xenografts in mice. To evaluate whether the response of ovarian cancer cells to pitavastatin... Read More about Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells.

The occurrence of seismites in the Upper Silurian Whitcliffe Formation of the old Whitcliffe quarry, Ludlow (2017)
Journal Article
(2017). The occurrence of seismites in the Upper Silurian Whitcliffe Formation of the old Whitcliffe quarry, Ludlow

Sediments exposed in the old Whitcliffe quarry west of Ludford Bridge, Ludlow are micaceous, calcareous siltstones representing a transition from shallow marine to terrestrial environments. Two deformed beds (20 cm and 40 cm thick) are exposed, sandw... Read More about The occurrence of seismites in the Upper Silurian Whitcliffe Formation of the old Whitcliffe quarry, Ludlow.

Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites (2017)
Journal Article
Wastling. (2017). Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites. Parasitology Research, 2707 -2719. https://doi.org/10.1007/s00436-017-5579-7

Toxoplasma gondii and Neospora caninum are closely related intracellular protozoan parasites and tissue cyst-forming Coccidia of the phylum Apicomplexa. There are remarkable similarities between the morphology, genomes and transcriptomes of both para... Read More about Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites.