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Novel similarity measure for interval-valued data based on overlapping ratio (2017)
Conference Proceeding
Kabir, S., Wagner, C., Havens, T. C., Anderson, D. T., & Aickelin, U. (2017). Novel similarity measure for interval-valued data based on overlapping ratio. . https://doi.org/10.1109/fuzz-ieee.2017.8015623

In computing the similarity of intervals, current similarity measures such as the commonly used Jaccard and Dice measures are at times not sensitive to changes in the width of intervals, producing equal similarities for substantially different pairs... Read More about Novel similarity measure for interval-valued data based on overlapping ratio.

The British Society for Rheumatology Guideline for the Management of Gout (2017)
Journal Article
Mallen, C., & Roddy, E. (2017). The British Society for Rheumatology Guideline for the Management of Gout. Rheumatology, 56(7), E1-E20. https://doi.org/10.1093/rheumatology/kex156

OBJECTIVES: We previously found large variations in general practitioner (GP) hypertension treatment probability in oldest-old (>80 years) between countries. We wanted to explore whether differences in country-specific cardiovascular disease (CVD) bu... Read More about The British Society for Rheumatology Guideline for the Management of Gout.

Internal dynamics condition centennial-scale oscillations in marine-based ice stream retreat (2017)
Journal Article
Smedley, R., Chiverrell, R., Ballantyne, C., Burke, M., Clark, C., Duller, G., …Thomas, G. (2017). Internal dynamics condition centennial-scale oscillations in marine-based ice stream retreat. Geology, 49(5), 787–790. https://doi.org/10.1130/G38991.1

Rates of ice stream retreat over decades can be determined from repeated satellite surveys and over millennia by palaeoenvironmental reconstructions. Centennial time scales are an important temporal gap in geological observations of value in process... Read More about Internal dynamics condition centennial-scale oscillations in marine-based ice stream retreat.

How to get the most from your summer placement (2017)
Journal Article
Gunnell, K. . A., & Neville, K. (2017). How to get the most from your summer placement. Pharmaceutical Journal, https://doi.org/10.1211/PJ.2017.20203274

You have been successful in your application for a summer placement, but now what? In this article, teaching fellow Karen Gunnell and academic clinical educator Kerry Neville discuss with Angela Kam what to do and what not to do before, during, and a... Read More about How to get the most from your summer placement.

Patients’ understanding and attitudes towards infliximab and etanercept biosimilars: result of a UK web-based survey. (2017)
Journal Article
(2017). Patients’ understanding and attitudes towards infliximab and etanercept biosimilars: result of a UK web-based survey. BioDrugs, 439-446

Background Infliximab and etanercept biosimilars present significant potential cost savings to the NHS. Patients need to be involved in the decision to use these medicines but there is limited published literature on their knowledge and attitudes ab... Read More about Patients’ understanding and attitudes towards infliximab and etanercept biosimilars: result of a UK web-based survey..

Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival (2017)
Journal Article
(2017). Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival. Bioscience Reports, https://doi.org/10.1042/BSR20170843

The E3 ubiquitin ligase RNF168 is a ring finger protein that has previously been identified to play an important regulatory role in the repair of double-strand DNA breaks.  In the present study, an unbiased forward genetics functional screen in mouse... Read More about Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival.

Antarctic climate and ice sheet configuration during a peak-warmth Early Pliocene interglacial at 4.23?Ma (2017)
Journal Article
(2017). Antarctic climate and ice sheet configuration during a peak-warmth Early Pliocene interglacial at 4.23?Ma. Climate of the Past Discussions, 959-975. https://doi.org/10.5194/cp-13-959-2017

The geometry of Antarctic ice sheets during warm periods of the geological past is difficult to determine from geological evidence, but is important to know because such reconstructions enable a more complete understanding of how the ice-sheet system... Read More about Antarctic climate and ice sheet configuration during a peak-warmth Early Pliocene interglacial at 4.23?Ma.

Testing a one-dimensional prescription of dynamical shear mixing with a two-dimensional hydrodynamic simulation (2017)
Journal Article
Edelman, P., Röpke, F., Hirschi, R., Georgy, C., & Jones, S. (2017). Testing a one-dimensional prescription of dynamical shear mixing with a two-dimensional hydrodynamic simulation. Astronomy and Astrophysics, 604, Article A25. https://doi.org/10.1051/0004-6361/201629873

Context. The treatment of mixing processes is still one of the major uncertainties in 1D stellar evolution models. This is mostly due to the need to parametrize and approximate aspects of hydrodynamics in hydrostatic codes. In particular, the effect... Read More about Testing a one-dimensional prescription of dynamical shear mixing with a two-dimensional hydrodynamic simulation.

A tale of three cities - OmegaCAM discovers multiple sequences in the color-magnitude diagram of the Orion Nebula Cluster (2017)
Journal Article
Wright, N. J. (2017). A tale of three cities - OmegaCAM discovers multiple sequences in the color-magnitude diagram of the Orion Nebula Cluster. Astronomy and Astrophysics, A22 - A22. https://doi.org/10.1051/0004-6361/201730432

As part of the accretion discs in Ha with OmegaCAM (ADHOC) survey, we imaged a region of 12 × 8 square degrees around the Orion Nebula Cluster in r, i and Ha. Thanks to the high-quality photometry obtained, we discovered three well-separated pre-main... Read More about A tale of three cities - OmegaCAM discovers multiple sequences in the color-magnitude diagram of the Orion Nebula Cluster.

Antarctic climate and ice-sheet configuration during the early Pliocene interglacial at 4.23Ma (2017)
Journal Article
(2017). Antarctic climate and ice-sheet configuration during the early Pliocene interglacial at 4.23Ma. Climate of the Past, 959 - 975. https://doi.org/10.5194/cp-13-959-2017

The geometry of Antarctic ice sheets during warm periods of the geological past is difficult to determine from geological evidence, but is important to know because such reconstructions enable a more complete understanding of how the ice-sheet system... Read More about Antarctic climate and ice-sheet configuration during the early Pliocene interglacial at 4.23Ma.

Patient's Understanding and Attititudes Towards Infliximab and Etanercept Biosimilars (2017)
Journal Article
(2017). Patient's Understanding and Attititudes Towards Infliximab and Etanercept Biosimilars. BioDrugs, 1-8. https://doi.org/10.1007/s40259-017-0238-1

Background Infliximab and etanercept biosimilars present significant potential cost savings to the NHS. Patients need to be involved in the decision to use these medicines but there is a limited published literature on their knowledge and attitudes... Read More about Patient's Understanding and Attititudes Towards Infliximab and Etanercept Biosimilars.

Synthesis and organogelating behaviour of amino acid-functionalised triphenylenes (2017)
Journal Article
Meegan, J. E., Yang, X., Rungsirisakun, R., Cosgrove, S. C., Bushby, R. J., Sadeghpour, A., …Ansell, R. J. (in press). Synthesis and organogelating behaviour of amino acid-functionalised triphenylenes. Soft Matter, 13(35), 5922-5932. https://doi.org/10.1039/c7sm00676d

Four novel amino acid-functionalised triphenylenes have been prepared with glycine, L-alanine, L-phenylalanine and L-tryptophan ethyl ester side-chains. The glycine derivative is a good gelator of chloroform, the alanine derivative gels ethanol and t... Read More about Synthesis and organogelating behaviour of amino acid-functionalised triphenylenes.

Hand dysfunction after transradial artery catheterization for coronary procedures (2017)
Journal Article
Ayyaz Ul Haq, M., Rashid, M., Shing Kwok, C., Wai Wong, C., Nolan, J., & Mamas, M. A. (2017). Hand dysfunction after transradial artery catheterization for coronary procedures. World Journal of Cardiology, 9(7), 609-619. https://doi.org/10.4330/wjc.v9.i7.609

AIM To sythesize the available literature on hand dysfunction after transradial catheterization. METHODS We searched MEDLINE and EMBASE. The search results were reviewed by two independent judicators for studies that met the inclusion criteria a... Read More about Hand dysfunction after transradial artery catheterization for coronary procedures.

G-quadruplexes: prediction, characterization, and biological application (2017)
Journal Article
(2017). G-quadruplexes: prediction, characterization, and biological application. Trends in Biotechnology, 997-1013. https://doi.org/10.1016/j.tibtech.2017.06.012

Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention for decades. Recent me... Read More about G-quadruplexes: prediction, characterization, and biological application.

Increase in body weight over a two-year period is associated with an increase in midfoot pressure and foot pain (2017)
Journal Article
(2017). Increase in body weight over a two-year period is associated with an increase in midfoot pressure and foot pain. Journal of Foot and Ankle Research, https://doi.org/10.1186/s13047-017-0214-5

Background There is a well-recognised relationship between body weight, plantar pressures and foot pain, but the temporal association between these factors is unknown. The aim of this study was to investigate the relationships between increasing wei... Read More about Increase in body weight over a two-year period is associated with an increase in midfoot pressure and foot pain.