Towards an understanding of amyloidogenesis: a structural and biophysical analysis of transthyretin
(2018)
Thesis
Yee, A. W. (2018). Towards an understanding of amyloidogenesis: a structural and biophysical analysis of transthyretin. (Thesis). Keele University
Human transthyretin (TTR) is heavily implicated in a range of fatal amyloid diseases. The propensity to form amyloid varies between wild-type TTR and various mutants. In all cases this occurs by tetramer dissociation to a monomeric form, which in tur... Read More about Towards an understanding of amyloidogenesis: a structural and biophysical analysis of transthyretin.