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A full-field 3D digital image correlation and modelling technique to characterise anterior cruciate ligament mechanics ex vivo. (2020)
Journal Article
(2020). A full-field 3D digital image correlation and modelling technique to characterise anterior cruciate ligament mechanics ex vivo. Acta biomaterialia, 417-428. https://doi.org/10.1016/j.actbio.2020.07.003

It is limiting to use conventional methods when characterising material properties of complex biological tissues with inhomogeneous and anisotropic structure, such as the anterior cruciate ligament (ACL) in the knee joint. This study aims to develop... Read More about A full-field 3D digital image correlation and modelling technique to characterise anterior cruciate ligament mechanics ex vivo..

Single-dwell treatment with a low-sodium solution in hypertensive peritoneal dialysis patients. (2020)
Journal Article
Davies. (2020). Single-dwell treatment with a low-sodium solution in hypertensive peritoneal dialysis patients. https://doi.org/10.1177/0896860820924136

BACKGROUND: Patients on peritoneal dialysis (PD) may suffer from sodium (Na) and fluid overload, hypertension and increased cardiovascular risk. Low-Na dialysis solution, by increasing the diffusive removal of Na, might improve blood pressure (BP) ma... Read More about Single-dwell treatment with a low-sodium solution in hypertensive peritoneal dialysis patients..

Feasibility and Face Validity of Outcome Measures for Use in Future Studies of Polymyalgia Rheumatica: An OMERACT Study (2020)
Journal Article
Yates, M., Owen, C. E., Muller, S., Graham, K., Neill, L., Twohig, H., …Working Group, O. P. (2020). Feasibility and Face Validity of Outcome Measures for Use in Future Studies of Polymyalgia Rheumatica: An OMERACT Study. Journal of Rheumatology, 47(9), 1379-1384. https://doi.org/10.3899/jrheum.190575

OBJECTIVE: The aim of this study was to survey participants with PMR to evaluate the face validity, acceptability and domain match of proposed candidate outcome measures. METHODS: A structured, online, anonymous survey was disseminated by patient sup... Read More about Feasibility and Face Validity of Outcome Measures for Use in Future Studies of Polymyalgia Rheumatica: An OMERACT Study.

SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018 (2020)
Presentation / Conference
Robinson, D., Craig, R., Lane, J., Andrew, A., Bailey, J., Yu, D., …Prieto-Alhambra, D. (2020, August). SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018. Poster presented at World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020), Spain (virtual)

Objective: Recent RCTs have demonstrated little efficacy of certain shoulder surgeries. To investigate the trend in shoulder surgery incidence over time overall and by surgery type. Methods: Data were obtained from UK primary care electronic healt... Read More about SECULAR TRENDS IN SHOULDER SURGERY IN THE UK BETWEEN 2000-2018.

Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis (2020)
Journal Article
Lau, T. S., Chan, L. K. Y., Man, G. C. W., Wong, C. H., Lee, J. H. S., Yim, S. F., …Kwong, J. (2020). Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis. Cancer Immunology Research, 8(8), 1099-1111. https://doi.org/10.1158/2326-6066.CIR-19-0616

Emerging evidence shows that the efficacy of chemotherapeutic drugs is reliant on their capability to induce immunogenic cell death (ICD), thus transforming dying tumor cells into antitumor vaccines. We wanted to uncover potential therapeutic strateg... Read More about Paclitaxel Induces Immunogenic Cell Death in Ovarian Cancer via TLR4/IKK2/SNARE-Dependent Exocytosis.

Virtual patients as a tool for training pre-registration pharmacists and increasing their preparedness to practice: A qualitative study (2020)
Journal Article
Thompson, J., White, S., & Chapman, S. (2020). Virtual patients as a tool for training pre-registration pharmacists and increasing their preparedness to practice: A qualitative study. PloS one, 15(8), Article e0238226. https://doi.org/10.1371/journal.pone.0238226

Virtual patients are an active learning pedagogical tool which simulate clinical scenarios in a three-dimensional environment. Their use in pharmacy education is under-researched in comparison to other healthcare professions. In the United Kingdom, p... Read More about Virtual patients as a tool for training pre-registration pharmacists and increasing their preparedness to practice: A qualitative study.

The impact of COVID-19 on percutaneous coronary intervention for ST-elevation myocardial infarction. (2020)
Journal Article
Mamas. (2020). The impact of COVID-19 on percutaneous coronary intervention for ST-elevation myocardial infarction. Heart, 1805-1811. https://doi.org/10.1136/heartjnl-2020-317650

Background The objective of the study was to identify any changes in primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) in England by analysing procedural numbers, clinical characteristics and patient outc... Read More about The impact of COVID-19 on percutaneous coronary intervention for ST-elevation myocardial infarction..

Questions and answers on workup diagnosis and risk stratification: a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation (2020)
Journal Article
Mamas, M. (2020). Questions and answers on workup diagnosis and risk stratification: a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal, https://doi.org/10.1093/eurheartj/ehaa602

Guidelines.

Guidance for Implementing Best Practice Therapeutic Exercise for Patients With Knee and Hip Osteoarthritis: What Does the Current Evidence Base Tell Us? (2020)
Journal Article
Holden, M. A., Button, K., Collins, N. J., Henrotin, Y., Hinman, R. S., Larsen, J. B., …Bennell, K. (2021). Guidance for Implementing Best Practice Therapeutic Exercise for Patients With Knee and Hip Osteoarthritis: What Does the Current Evidence Base Tell Us?. Arthritis Care and Research, 73(12), 1746-1753. https://doi.org/10.1002/acr.24434

Therapeutic exercise is a recommended first‐line treatment for patients with knee and hip osteoarthritis (OA); however, there is little specific advice or practical resources to guide clinicians in its implementation. As the first in a series of proj... Read More about Guidance for Implementing Best Practice Therapeutic Exercise for Patients With Knee and Hip Osteoarthritis: What Does the Current Evidence Base Tell Us?.

The use of multiplex staining to measure the density and clustering of four endometrial immune cells around the implantation period in women with recurrent miscarriage: comparison with fertile controls (2020)
Journal Article
Zhao, Y., Chen, X., Zhang, T., Chan, L. K. Y., Liu, Y., Chung, J. P., …Li, T. (2020). The use of multiplex staining to measure the density and clustering of four endometrial immune cells around the implantation period in women with recurrent miscarriage: comparison with fertile controls. Journal of Molecular Histology, 51(5), 593-603. https://doi.org/10.1007/s10735-020-09908-2

The Governance of British Higher Education: The Impact of Governmental, Financial and Market Pressures: By Michael Shattock and Aniko Horvath. Pp198 + xxiii. London: Bloomsbury Academic. 2020. £81 (hbk). ISBN 978-1350074026 (hbk). (2020)
Journal Article
Howlett, J. (2021). The Governance of British Higher Education: The Impact of Governmental, Financial and Market Pressures: By Michael Shattock and Aniko Horvath. Pp198 + xxiii. London: Bloomsbury Academic. 2020. £81 (hbk). ISBN 978-1350074026 (hbk). British Journal of Educational Studies, 69(1), 129-131. https://doi.org/10.1080/00071005.2020.1810482

Antimicrobial resistance preparedness in sub-Saharan African countries (2020)
Journal Article
Abdel Hamid, M., Haider, N., Kock, R., Ippolito, G., Zumla, A., McHugh, T., …Ntoumi, F. (2020). Antimicrobial resistance preparedness in sub-Saharan African countries. Antimicrobial Resistance and Infection Control, 9, Article 145. https://doi.org/10.1186/s13756-020-00800-y

Background Antimicrobial resistance (AMR) is of growing concern globally and AMR status in sub-Saharan Africa (SSA) is undefined due to a lack of real-time data recording, surveillance and regulation. World Health Organization (WHO) Joint External E... Read More about Antimicrobial resistance preparedness in sub-Saharan African countries.

A global pandemic is not a good time to introduce ‘opt-out’ for organ donation (2020)
Journal Article
Parsons. (2020). A global pandemic is not a good time to introduce ‘opt-out’ for organ donation. Medical Law International, 155 - 166. https://doi.org/10.1177/0968533220950002

Following several international examples, England introduced a system of deemed consent for organ donation in May 2020. This had been planned for over a year. However, the unprecedented circumstances of the COVID-19 pandemic raise issues that make t... Read More about A global pandemic is not a good time to introduce ‘opt-out’ for organ donation.