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Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review (2021)
Journal Article
Ng, C. Y., Chai, J. Y., Foo, J. B., Mohamad Yahaya, N. H., Yang, Y., Ng, M. H., & Law, J. X. (in press). Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review. International Journal of Nanomedicine, Volume 16, 6749-6781. https://doi.org/10.2147/ijn.s327059

Treatment of cartilage defects such as osteoarthritis (OA) and osteochondral defect (OCD) remains a huge clinical challenge in orthopedics. OA is one of the most common chronic health conditions and is mainly characterized by the degeneration of arti... Read More about Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review.

Development and evaluation of a novel virtual agent-based app for patients with colorectal cancer: A mixed methods study (2021)
Thesis
Chatzixenitidis, A. (2021). Development and evaluation of a novel virtual agent-based app for patients with colorectal cancer: A mixed methods study. (Thesis). Keele University

Background and aim: Information support is an integral part of cancer care, but its provision can be problematic in busy health settings. The aim of this project was to develop and evaluate a health app to facilitate the provision of information supp... Read More about Development and evaluation of a novel virtual agent-based app for patients with colorectal cancer: A mixed methods study.

Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice (2021)
Thesis
Lawton, S. A. (2021). Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice. (Thesis). Keele University

Background: There are a range of data collection methodologies employed for collecting patient health related research data. Within primary care settings, and particularly within general practice, time and resources are limited. The utility of an aut... Read More about Automated Check-in Data Collection (AC DC): an investigation of utility, acceptability and effectiveness in general practice.

Antiproliferative, proapoptotic and DNA methylation activity of sesqui- and diterpenoids in ovarian cancer cells (2021)
Thesis
Fadayomi, I. E. (2021). Antiproliferative, proapoptotic and DNA methylation activity of sesqui- and diterpenoids in ovarian cancer cells. (Thesis). Keele University

Ovarian cancer is a gynaecological malignancy associated with the highest level of death. Its resistance against anti-cancer drugs in recent time has exacerbated the problem. Hence, the search for novel drugs from plants used in traditional medicine... Read More about Antiproliferative, proapoptotic and DNA methylation activity of sesqui- and diterpenoids in ovarian cancer cells.

An investigation into the biosynthesis of cuticular hydrocarbons in British ants using isotopically labelled diets and gas chromatography - mass spectrometry (2021)
Thesis
Shemilt, S. J. (2021). An investigation into the biosynthesis of cuticular hydrocarbons in British ants using isotopically labelled diets and gas chromatography - mass spectrometry. (Thesis). Keele University

Ants are one of only four groups which can be classed as being truly social, that is they demonstrate altruistic behaviours towards nestmates. However in order to do this there must be a complex nestmate recognition signal at work. This signal is gen... Read More about An investigation into the biosynthesis of cuticular hydrocarbons in British ants using isotopically labelled diets and gas chromatography - mass spectrometry.

Convective boundary structure and mixing in stellar interiors (2021)
Thesis
Scott, L. J. A. (2021). Convective boundary structure and mixing in stellar interiors. (Thesis). Keele University

The treatment of convection remains one of the key uncertainties in stellar evolution. In particular, mixing processes at the boundaries of convective regions are complex and diffcult to define analytically. Therefore, hydrodynamic simulations are us... Read More about Convective boundary structure and mixing in stellar interiors.

The sedimentary architecture and spatial variations of dryland ephemeral fluvial systems (2021)
Thesis
Priddy, C. L. (2021). The sedimentary architecture and spatial variations of dryland ephemeral fluvial systems. (Thesis). Keele University

Ancient dryland continental basins commonly comprise sedimentary fill that records the activity of both fluvial and aeolian environments. Despite extensive studies of dryland ephemeral fluvial systems, detailed three dimensional facies models for the... Read More about The sedimentary architecture and spatial variations of dryland ephemeral fluvial systems.

Magma storage and differentiation in volcanic arcs: examples from the central Aeolian arc, Italy (2021)
Thesis
Wiltshire, R. E. (2021). Magma storage and differentiation in volcanic arcs: examples from the central Aeolian arc, Italy. (Thesis). Keele University

The Aeolian arc is characterised by its complex geodynamic setting, with a heterogeneous mantle source and differing extents of shallow-level magmatic processes. These processes result in large within arc geochemical variations influencing the magma... Read More about Magma storage and differentiation in volcanic arcs: examples from the central Aeolian arc, Italy.

“Partial solutions to the menace”: Philip K. Dick and the Politics of Genre (2021)
Thesis
Johnston Jones, R. D. (2021). “Partial solutions to the menace”: Philip K. Dick and the Politics of Genre. (Thesis). Keele University

In an essay published in 1955, titled ‘Pessimism in Science Fiction’, Philip K. Dick posits that science fiction (sf) cannot function as social critique without conveying a tentative utopian impulse: a “partial solution to the menace”. In the unfoldi... Read More about “Partial solutions to the menace”: Philip K. Dick and the Politics of Genre.

1. Modern English. 2. The regenerating city: space, hauntings and youth culture in the post-millennial Manchester novel (2021)
Thesis
Gufar, S. (2021). 1. Modern English. 2. The regenerating city: space, hauntings and youth culture in the post-millennial Manchester novel. (Thesis). Keele University

My thesis investigates space, hauntings and youth culture in Manchester with two projects: a novel and a critical dissertation. The novel is a coming-of-age story that takes place in Ashton-under-Lyne. Modern English explores the experience of gro... Read More about 1. Modern English. 2. The regenerating city: space, hauntings and youth culture in the post-millennial Manchester novel.

Applying analytical chemistry techniques to the characterisation of mine spoils and assessing treatments for minimising their environmental impacts (2021)
Thesis
Alhar, M. A. M. (2021). Applying analytical chemistry techniques to the characterisation of mine spoils and assessing treatments for minimising their environmental impacts. (Thesis). Keele University

Mining activities can leave a legacy of contamination with the potential to threaten the wider environment and human health. This is particularly so with historic mines that pre-date modern restoration and environmental protection measures. This stud... Read More about Applying analytical chemistry techniques to the characterisation of mine spoils and assessing treatments for minimising their environmental impacts.

Patient-related factors influencing management and procedural outcomes of de novo cardiac electronic device implantation (2021)
Thesis
Mohamed, M. O. A. H. (2021). Patient-related factors influencing management and procedural outcomes of de novo cardiac electronic device implantation. (Thesis). Keele University

Cardiac implantable electronic devices (CIED) are an essential part of the management of patients with life threatening arrhythmias. While many patient-related factors have been previously shown to play a role in the choice of CIED type offered to pa... Read More about Patient-related factors influencing management and procedural outcomes of de novo cardiac electronic device implantation.

Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic (2021)
Journal Article
Shoaib, A., Van Spall, H. G. C., Wu, J., Cleland, J. G. F., McDonagh, T. A., Rashid, M., …Mamas, M. A. (2021). Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal - Quality of Care and Clinical Outcomes, 7(4), 378-387. https://doi.org/10.1093/ehjqcco/qcab040

Aims We hypothesized that a decline in admissions with heart failure during COVID-19 pandemic would lead to a reciprocal rise in mortality for patients with heart failure in the community. Methods and results We used National Heart Failure Audit d... Read More about Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic.

Agency, Free Will, Self-Constitution: New Concepts for Historians of German-Jewish History between 1914 and 1938? (2021)
Journal Article
Kauders, A. (2021). Agency, Free Will, Self-Constitution: New Concepts for Historians of German-Jewish History between 1914 and 1938?. Leo Baeck Institute Yearbook, https://doi.org/10.1093/leobaeck/ybab005

This article discusses recent work on German-Jewish agency between 1914 and 1938. To find out whether ‘agency’ might be a helpful category for examining the crises facing Central European Jewry in this period, the article addresses the subject from t... Read More about Agency, Free Will, Self-Constitution: New Concepts for Historians of German-Jewish History between 1914 and 1938?.

The Study of Identity in Health Psychology (2021)
Book Chapter
Locke, A., & Montague, J. (2021). The Study of Identity in Health Psychology. In The Cambridge Handbook of Identity (508-528). Cambridge University Press. https://doi.org/10.1017/9781108755146.027

In this chapter we consider the ways in which the study of identities has been approached in Critical Health Psychology. Critical approaches to health psychology move away from individualistic concerns to consider the ways in which wider social-psych... Read More about The Study of Identity in Health Psychology.

Upper Cretaceous calcareous nannofossil biostratigraphy of the East European Platform: A proposed regional nannofossil zonation scheme and correlation with foraminifera and radiolarian zones (2021)
Book Chapter
Ovechkina, M. N., Kopaevich, L. F., Vishnevskaya, V. S., & Mostovski, M. B. (2021). Upper Cretaceous calcareous nannofossil biostratigraphy of the East European Platform: A proposed regional nannofossil zonation scheme and correlation with foraminifera and radiolarian zones. In M. Montenari (Ed.), Stratigraphy & Timescales (293-437). Elsevier. https://doi.org/10.1016/bs.sats.2021.09.004

The Upper Cretaceous deposits are broadly distributed over the territory of the East European Platform (EEP), yet they cannot be reliably subdivided on the basis of the calcareous nannofossils using the existing global and provincial zonal schemes du... Read More about Upper Cretaceous calcareous nannofossil biostratigraphy of the East European Platform: A proposed regional nannofossil zonation scheme and correlation with foraminifera and radiolarian zones.

Glyceryl Trinitrate: History, Mystery, and Alcohol Intolerance (2021)
Journal Article
Pearson. (2021). Glyceryl Trinitrate: History, Mystery, and Alcohol Intolerance. Molecules, 6581 - 6581. https://doi.org/10.3390/molecules26216581

Glyceryl trinitrate (GTN) is one of the earliest known treatments for angina with a fascinating history that bridges three centuries. However, despite its central role in the nitric oxide (NO) story as a NO-donating compound, establishing the precise... Read More about Glyceryl Trinitrate: History, Mystery, and Alcohol Intolerance.

The Gaia-ESO Survey: Membership probabilities for stars in 63 open and 7 globular clusters from 3D kinematics (2021)
Journal Article
Wright, & Jeffries. (2021). The Gaia-ESO Survey: Membership probabilities for stars in 63 open and 7 globular clusters from 3D kinematics. Monthly Notices of the Royal Astronomical Society, https://doi.org/10.1093/mnras/stab3032

Spectroscopy from the final internal data release of the Gaia-ESO Survey (GES) has been combined with Gaia EDR3 to assign membership probabilities to targets observed towards 63 Galactic open clusters and 7 globular clusters. The membership probabili... Read More about The Gaia-ESO Survey: Membership probabilities for stars in 63 open and 7 globular clusters from 3D kinematics.