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The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients (2021)
Journal Article
Su, Y., Chen, Y., Tseng, Y., Shieh, G., Wu, P., Shiau, A., & Wu, C. (2021). The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients. Cells, 10(10), Article 2642. https://doi.org/10.3390/cells10102642

The embryonic stem cell marker Oct4 is expressed in several human cancers and is positively correlated with a poor outcome in cancer patients. However, its physiological role in cancer progression remains poorly understood. Tumor cells block apoptosi... Read More about The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients.

Racial disparities in management and outcomes of out-of-hospital cardiac arrest complicating myocardial infarction; a national study from England and Wales (2021)
Journal Article
Mamas, & Rashid. (2021). Racial disparities in management and outcomes of out-of-hospital cardiac arrest complicating myocardial infarction; a national study from England and Wales. https://doi.org/10.1016/j.cjco.2021.09.026

Background Studies of racial disparities in patients admitted with an OHCA in the setting of AMI have shown inconsistent results. Whether these differences in care exist in a universal healthcare system in England is unknown. Methods Patients admitte... Read More about Racial disparities in management and outcomes of out-of-hospital cardiac arrest complicating myocardial infarction; a national study from England and Wales.

Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature (2021)
Journal Article
Migliorini, F., La Padula, G., Torsiello, E., Spiezia, F., Oliva, F., & Maffulli, N. (2021). Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature. European Journal of Medical Research, 26(1), Article ARTN 118. https://doi.org/10.1186/s40001-021-00593-9

Large bone defects resulting from musculoskeletal tumours, infections, or trauma are often unable to heal spontaneously. The challenge for surgeons is to avoid amputation, and provide the best functional outcomes. Allograft, vascularized fibular or i... Read More about Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature.

Trust Beliefs in Significant Others, Interpersonal Stress, and Internalizing Psychopathology of Adolescents with Psychiatric Disorders. (2021)
Journal Article
(2021). Trust Beliefs in Significant Others, Interpersonal Stress, and Internalizing Psychopathology of Adolescents with Psychiatric Disorders. Child Psychiatry and Human Development, https://doi.org/10.1007/s10578-021-01255-x

This study examined relations between trust beliefs in significant others (TBSO), interpersonal stress, and internalizing psychopathology for adolescents with psychiatric disorders. Two hundred and thirty-four adolescents from an acute inpatient unit... Read More about Trust Beliefs in Significant Others, Interpersonal Stress, and Internalizing Psychopathology of Adolescents with Psychiatric Disorders..

Investigation of the blood proteome in response to spinal cord injury in rodent models (2021)
Journal Article
Hulme, C. H., Fuller, H. R., Riddell, J., Shirran, S. L., Botting, C. H., Osman, A., & Wright, K. T. (2022). Investigation of the blood proteome in response to spinal cord injury in rodent models. Spinal Cord, 60(4), 320-325. https://doi.org/10.1038/s41393-021-00692-8

STUDY DESIGN: Explanatory and Mechanistic Study OBJECTIVES: A better understanding of the ‘whole-body’ response following spinal cord injury (SCI) is needed to guide future research aimed at developing novel therapeutic interventions and identifying... Read More about Investigation of the blood proteome in response to spinal cord injury in rodent models.

Clinical validation of the Oswestry-Bristol Classification as part of a decision algorithm for trochlear dysplasia surgery (2021)
Journal Article
Sharma, N., Rehmatullah, N., Kuiper, J. H., Gallacher, P., & Barnett, A. J. (2021). Clinical validation of the Oswestry-Bristol Classification as part of a decision algorithm for trochlear dysplasia surgery. The Bone & Joint Journal, 103-B(10), 1586-1594. https://doi.org/10.1302/0301-620x.103b10.bjj-2020-1984.r1

The Oswestry-Bristol Classification (OBC) is an MRI-specific assessment tool to grade trochlear dysplasia. The aim of this study is to validate clinically the OBC by demonstrating its use in selecting treatments that are safe and effective.

In-hospital outcomes of endovascular versus surgical revascularization for chronic total occlusion in peripheral artery disease. (2021)
Journal Article
Mamas. (2021). In-hospital outcomes of endovascular versus surgical revascularization for chronic total occlusion in peripheral artery disease. Catheterization and Cardiovascular Interventions, E586 - E593. https://doi.org/10.1161/circinterventions.119.008150

BACKGROUND: The outcome of endovascular intervention (EVI) compared vs. surgical revascularization in patients with peripheral artery disease (PAD) due to chronic total occlusion (CTO) is unknown. METHODS: Using the National Inpatient Sample database... Read More about In-hospital outcomes of endovascular versus surgical revascularization for chronic total occlusion in peripheral artery disease..

Distribution, management and outcomes of AMI according to principal diagnosis priority during inpatient admission. (2021)
Journal Article
Mamas. (2021). Distribution, management and outcomes of AMI according to principal diagnosis priority during inpatient admission. https://doi.org/10.1111/ijcp.14554

BACKGROUND: In recent years, there has been a growing interest in outcomes of patients with acute myocardial infarction (AMI) using large administrative datasets. The present study was designed to compare the characteristics, management strategies an... Read More about Distribution, management and outcomes of AMI according to principal diagnosis priority during inpatient admission..

Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial. (2021)
Journal Article
Mamas. (2021). Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial. European Heart Journal, 3844 - 3852. https://doi.org/10.1093/eurheartj/ehab444

AIMS: Fractional flow reserve (FFRCT) using computed tomography coronary angiography (CTCA) determines both the presence of coronary artery disease and vessel-specific ischaemia. We tested whether an evaluation strategy based on FFRCT would improve e... Read More about Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial..

Effect of the Timing of Admission of Out of Hospital Cardiac Arrest Complicating Acute Myocardial Infarction on Management and Outcome. (2021)
Journal Article
(2021). Effect of the Timing of Admission of Out of Hospital Cardiac Arrest Complicating Acute Myocardial Infarction on Management and Outcome. https://doi.org/10.1016/j.amjcard.2021.06.042

There is limited data regarding the impact of time of admission on clinical outcomes of out of hospital cardiac arrest (OHCA) complicating acute myocardial infarction (AMI). We investigated the patient characteristics, management, and outcomes of OHC... Read More about Effect of the Timing of Admission of Out of Hospital Cardiac Arrest Complicating Acute Myocardial Infarction on Management and Outcome..

Comparison of Outcomes of Patients With Versus Without Chronic Liver Disease Undergoing Percutaneous Coronary Intervention. (2021)
Journal Article
Mamas. (2021). Comparison of Outcomes of Patients With Versus Without Chronic Liver Disease Undergoing Percutaneous Coronary Intervention. American Journal of Cardiology, 32 - 38. https://doi.org/10.1016/j.amjcard.2021.06.044

There are limited data on the outcomes of chronic liver disease (CLD) patients admitted for percutaneous coronary intervention (PCI). All PCI hospitalizations from the Nationwide Inpatient Sample (2004 to 2015) were analyzed and stratified by the pre... Read More about Comparison of Outcomes of Patients With Versus Without Chronic Liver Disease Undergoing Percutaneous Coronary Intervention..

Body Mass Index and Body Satisfaction: Does Availability of Well-Fitting Clothes Matter? (2021)
Journal Article
Grogan, S., Gill, S., Brownbridge, K., McChesney, G., Wren, P., Cole, J., …Armitage, C. J. (2021). Body Mass Index and Body Satisfaction: Does Availability of Well-Fitting Clothes Matter?. Clothing and Textiles Research Journal, 251 - 263. https://doi.org/10.1177/0887302X20915528

Relatively little is known about the factors that mediate the relationship between high body mass index (BMI) and reduced body satisfaction. This is the first study to investigate whether availability of well-fitting clothes mediates this relationsh... Read More about Body Mass Index and Body Satisfaction: Does Availability of Well-Fitting Clothes Matter?.

Managing chronic wet cough in children: another piece of the puzzle. (2021)
Journal Article
Gilchrist. (2021). Managing chronic wet cough in children: another piece of the puzzle. Lancet Respiratory Medicine, 1078 - 1079. https://doi.org/10.1016/S2213-2600%2821%2900159-4

Chronic wet cough is the hallmark of chronic obstructive pulmonary disease in older people and bronchiectasis in adults and older children. In young children, the commonest cause of chronic wet cough is protracted bacterial bronchitis (PBB) but there... Read More about Managing chronic wet cough in children: another piece of the puzzle..

HD 183579b: a warm sub-Neptune transiting a solar twin detected by TESS (2021)
Journal Article
Hellier. (2021). HD 183579b: a warm sub-Neptune transiting a solar twin detected by TESS. Monthly Notices of the Royal Astronomical Society, 2220 - 2240. https://doi.org/10.1093/mnras/stab2224

We report the discovery and characterization of a transiting warm sub-Neptune planet around the nearby bright (V = 8.75 mag, K = 7.15 mag) solar twin HD 183579, delivered by the Transiting Exoplanet Survey Satellite (TESS). The host star is located 5... Read More about HD 183579b: a warm sub-Neptune transiting a solar twin detected by TESS.

Integration of Large-Scale Electric Vehicles into Utility Grid: An Efficient Approach for Impact Analysis and Power Quality Assessment (2021)
Journal Article
(2021). Integration of Large-Scale Electric Vehicles into Utility Grid: An Efficient Approach for Impact Analysis and Power Quality Assessment. Sustainability, https://doi.org/10.3390/su131910943

Electric vehicles (EVs) have received massive consideration in the automotive industries due to their improved performance, efficiency and capability to minimize global warming and carbon emission impacts. The utilization of EVs has several potential... Read More about Integration of Large-Scale Electric Vehicles into Utility Grid: An Efficient Approach for Impact Analysis and Power Quality Assessment.

Clinical Prediction Models in Sports Medicine: A Guide for Clinicians and Researchers. (2021)
Journal Article
(2021). Clinical Prediction Models in Sports Medicine: A Guide for Clinicians and Researchers. Journal of Orthopaedic & Sports Physical Therapy, 517 - 525. https://doi.org/10.2519/jospt.2021.10697

SYNOPSIS: Participating in sport carries inherent risk of injury. Clinicians execute high-level clinical reasoning and decision making to support athletes to achieve the best outcomes. Accurately diagnosing a problem, estimating prognosis, or selecti... Read More about Clinical Prediction Models in Sports Medicine: A Guide for Clinicians and Researchers..