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New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2. (2021)
Journal Article
Reynisson. (2021). New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2. Molecules, https://doi.org/10.3390/molecules27010072

A series of deoxycholic acid (DCA) amides containing benzyl ether groups on the steroid core were tested against the tyrosyl-DNA phosphodiesterase 1 (TDP1) and 2 (TDP2) enzymes. In addition, 1,2,4- and 1,3,4-oxadiazole derivatives were synthesized to... Read More about New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2..

THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS (2021)
Journal Article
Kay, A. G., Treadwell, K., Roach, P., Morgan, R., Lodge, R., Hyland, M., …Kehoe, O. (in press). THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS. International Journal of Molecular Sciences, 23(1), Article 126. https://doi.org/10.3390/ijms23010126

AbstractNovel biological therapies have revolutionised the management of Rheumatoid Arthritis (RA) but no cure currently exists. Mesenchymal stem cells (MSCs) immunomodulate inflammatory responses through paracrine signalling, including via secretion... Read More about THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS.

Development of an optimised physiotherapist-led treatment protocol for lateral elbow tendinopathy: a consensus study using an online nominal group technique (2021)
Journal Article
Bateman, M., Saunders, B., Littlewood, C., & Hill, J. (2021). Development of an optimised physiotherapist-led treatment protocol for lateral elbow tendinopathy: a consensus study using an online nominal group technique. BMJ Open, 11(12), Article e053841. https://doi.org/10.1136/bmjopen-2021-053841

OBJECTIVES: There are a wide range of physiotherapy treatment options for people with lateral elbow tendinopathy (LET); however, previous studies have reported inconsistent approaches to treatment and a lack of evidence demonstrating clinical effecti... Read More about Development of an optimised physiotherapist-led treatment protocol for lateral elbow tendinopathy: a consensus study using an online nominal group technique.

Indium(III) promoted oxidative P-P coupling of silylphosphines (2021)
Journal Article
Cartlidge, A. J., & Matthews, P. (2022). Indium(III) promoted oxidative P-P coupling of silylphosphines. Inorganica Chimica Acta, 120772 - 120772. https://doi.org/10.1016/j.ica.2021.120772

The reaction of indium(III) salts with Ph2PSiMe3 and PhP(SiMe3)2 gives rise to a one- and two-electron reductive P-P coupling respectively, with the formation of new P-P bonds resulting in the preparation of (Ph2P)2 and the cyclicoligophosphane compo... Read More about Indium(III) promoted oxidative P-P coupling of silylphosphines.

Relational and instrumental perspectives on compliance with the law among people experiencing homelessness. (2021)
Journal Article
Stott. (2021). Relational and instrumental perspectives on compliance with the law among people experiencing homelessness. Law and Human Behavior, 1-14. https://doi.org/10.1037/lhb0000465

OBJECTIVE: We conducted an exploratory study testing procedural justice theory with a novel population. We assessed the extent to which police procedural justice, effectiveness, legitimacy, and perceived risk of sanction predict compliance with the l... Read More about Relational and instrumental perspectives on compliance with the law among people experiencing homelessness..

Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis (2021)
Journal Article
Kay, A. G., Roach, P., Morgan, R., Lodge, R., Hyland, M., Piccinini, A. M., …Treadwell, K. (2021). Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis. International Journal of Molecular Sciences, 23(1), 126 - 126. https://doi.org/10.3390/ijms23010126

Mesenchymal stem cells (MSCs) immunomodulate inflammatory responses through paracrine signalling, including via secretion of extracellular vesicles (EVs) in the cell secretome. We evaluated the therapeutic potential of MSCs-derived small EVs in an an... Read More about Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis.

Necessity, Non-Violent Direct Activism, and the Stansted 15: Reasserting ‘Hoffmann's Bargain’ (2021)
Journal Article
Doherty. (2021). Necessity, Non-Violent Direct Activism, and the Stansted 15: Reasserting ‘Hoffmann's Bargain’. Modern Law Review, https://doi.org/10.1111/1468-2230.12715

In Thacker and ors the Court of Appeal overturned the convictions of the ‘Stansted 15’ due to a misdirection on the substantive offence. However, the court rejected their necessity defence, following Jones, as their actions were political, outweighin... Read More about Necessity, Non-Violent Direct Activism, and the Stansted 15: Reasserting ‘Hoffmann's Bargain’.

Emotional distress, anxiety and depression in South Asians with long-term conditions: a qualitative systematic review (2021)
Journal Article
Awan, H., Mughal, F., Kingstone, T., Chew-Graham, C., & Corp, N. (2022). Emotional distress, anxiety and depression in South Asians with long-term conditions: a qualitative systematic review. British Journal of General Practice (BJGP), 72(716), https://doi.org/10.3399/BJGP.2021.0345

Background: People with physical-mental comorbidity have a poorer quality of life, worse clinical outcomes and increased mortality compared to people with physical conditions alone. South Asians (SAs) are the largest minority group in the UK and a... Read More about Emotional distress, anxiety and depression in South Asians with long-term conditions: a qualitative systematic review.

Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis (2021)
Journal Article
Carroll, W., Green, J., & Gilchrist, F. J. (in press). Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis. Cochrane Database of Systematic Reviews, 2021(12), https://doi.org/10.1002/14651858.cd012619.pub3

Background Cystic fibrosis (CF) is the most common, life‐limiting, genetically inherited disease. It affects multiple organs, particularly the respiratory system. However, gastrointestinal problems such as constipation and distal intestinal obstruct... Read More about Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.

Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates (2021)
Journal Article
Karlsson, R., Chopra, P., Joshi, A., Yang, Z., Vakhrushev, S. Y., Clausen, T. M., …Miller, R. L. (2021). Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates. Science Advances, 7(52), https://doi.org/10.1126/sciadv.abl6026

Heparan sulfate (HS) polysaccharides are master regulators of diverse biological processes via sulfated motifs that can recruit specific proteins. 3-O-sulfation of HS/heparin is crucial for anticoagulant activity, but despite emerging evidence for ro... Read More about Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates.

Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis (2021)
Journal Article
Gilchrist, F. J., Green, J., & Carroll, W. (2021). Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD012798.pub3

BACKGROUND: Cystic fibrosis is the most common life-limiting autosomal recessive genetic disorder in white populations. Distal intestinal obstruction syndrome (DIOS) is an important morbidity in cystic fibrosis. It is the result of the accumulation o... Read More about Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.

Using COVID-19 vaccination as a resilience strategy for the tourism sector – evidence from Serbia (2021)
Journal Article
Mladenović, D., Rrustemi, V., & Mogaji, E. (2022). Using COVID-19 vaccination as a resilience strategy for the tourism sector – evidence from Serbia. Current Issues in Tourism, 25(7), 1021-1025. https://doi.org/10.1080/13683500.2021.2018407

This short communication discusses the inflow of foreign tourists during the current pandemic and its interplay with the wide-scale administration of COVID-19 vaccines in Serbia. It focuses on the country’s provision of free-of-charge vaccines to inb... Read More about Using COVID-19 vaccination as a resilience strategy for the tourism sector – evidence from Serbia.

Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study. (2021)
Journal Article
Mamas. (2021). Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study. https://doi.org/10.1016/j.jaccao.2021.11.001

Background: Myocardial infarction is a cardiac adverse event associated with 5-fluorouracil (5-FU). There are limited data on the incidence, risk, and prognosis of 5-FU-associated myocardial infarction. Objectives: The aim of this study was to examin... Read More about Risk for Myocardial Infarction Following 5-Fluorouracil Treatment in Patients With Gastrointestinal Cancer: A Nationwide Registry-Based Study..

Calcium sequestration by human platelet acidic organelles is regulated by the actin cytoskeleton and autocrine 5-hydroxytryptamine (2021)
Journal Article
Harper. (2022). Calcium sequestration by human platelet acidic organelles is regulated by the actin cytoskeleton and autocrine 5-hydroxytryptamine. Cell Calcium, 101, 102522 - 102522. https://doi.org/10.1016/j.ceca.2021.102522

Human platelets regulate agonist-evoked Ca2+ signalling through Ca2+ release from and sequestration into acidic organelles. Previous studies have pharmacologically characterised the presence of a Ca2+-H+ exchanger in these organelles. This exchanger... Read More about Calcium sequestration by human platelet acidic organelles is regulated by the actin cytoskeleton and autocrine 5-hydroxytryptamine.

Augment Human Resource Proximity Plumbing Cybernation (2021)
Book Chapter
Deogaonkar, A., Nanoty, S., Shrivastava, A., & Jain, G. (2022). Augment Human Resource Proximity Plumbing Cybernation. In Research Anthology on Human Resource Practices for the Modern Workforce (911-920). IGI Global. https://doi.org/10.4018/978-1-6684-3873-2.ch047

The expeditious proliferation of artificial intelligence in the mainstream has rejigged the simplest processes of the various sectors in the most efficient way. With the advent of the era of cybernation, the work culture has been curbed with the time... Read More about Augment Human Resource Proximity Plumbing Cybernation.

In-Hospital Characteristics and 30-Day Readmissions for Acute Myocardial Infarction and Major Bleeding in Patients With Active Cancer. (2021)
Journal Article
Mamas. (2021). In-Hospital Characteristics and 30-Day Readmissions for Acute Myocardial Infarction and Major Bleeding in Patients With Active Cancer. The American Journal of Cardiology, 25 - 37. https://doi.org/10.1016/j.amjcard.2021.11.015

There are limited data on readmission with ischemic and major bleeding events in patients with acute myocardial infarction (AMI) with active cancer. The purpose of our study was to evaluate in-hospital characteristics and 30-day readmission rates for... Read More about In-Hospital Characteristics and 30-Day Readmissions for Acute Myocardial Infarction and Major Bleeding in Patients With Active Cancer..

Meta-Analysis Comparing Apixaban Versus Rivaroxaban for Management of Patients With Nonvalvular Atrial Fibrillation. (2021)
Journal Article
Mamas. (2021). Meta-Analysis Comparing Apixaban Versus Rivaroxaban for Management of Patients With Nonvalvular Atrial Fibrillation. The American Journal of Cardiology, 58 - 64. https://doi.org/10.1016/j.amjcard.2021.11.021

To compare the efficacy and safety of apixaban and rivaroxaban for the prevention of stroke in patients with nonvalvular atrial fibrillation (NVAF) by way of a meta-analysis informed by real-world evidence. Systematic review and meta-analysis of obse... Read More about Meta-Analysis Comparing Apixaban Versus Rivaroxaban for Management of Patients With Nonvalvular Atrial Fibrillation..

Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study (2021)
Journal Article
(2021). Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study. JMIR Research Protocols, e19543 - e19543

Background There is a growing interest in using mobile apps to support communication, safety, and well-being. Evidence directly from people with dementia regarding the usability, usefulness, and relevance of mobile apps is limited. Objective This... Read More about Co-designing an Adaption of a Mobile App to Enhance Communication, Safety, and Well-being Among People Living at Home With Early-Stage Dementia: Protocol for an Exploratory Multiple Case Study.

Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial (2021)
Journal Article
Allison, K., Jones, S., Hinman, R. S., Briggs, A. M., Sumithran, P., Quicke, J., …Bennell, K. (2021). Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial. Arthritis Care and Research, 75(4), 835-847. https://doi.org/10.1002/acr.24828

OBJECTIVE: Evaluate effects of an online education program about weight management for osteoarthritis on physiotherapists' self-reported confidence in knowledge and skills in weight management, and attitudes toward obesity. METHOD: A two-group ran... Read More about Effects of an Online Education Program on Physical Therapists' Confidence in Weight Management for People With Osteoarthritis: A Randomized Controlled Trial.