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Effectiveness of stratified treatment for back pain in Danish primary care: A randomized controlled trial (2021)
Journal Article
Morsø, L., Olsen Rose, K., Schiøttz‐Christensen, B., Sowden, G., Søndergaard, J., & Christiansen, D. H. (2021). Effectiveness of stratified treatment for back pain in Danish primary care: A randomized controlled trial. European Journal of Pain, 25(9), 2020-2038. https://doi.org/10.1002/ejp.1818

Background A randomized controlled trial (RCT) of stratified care demonstrated superior clinical outcomes and cost-effectiveness for low back pain (LBP) patients in UK primary care. This is the first study in Europe, outside of the original UK study,... Read More about Effectiveness of stratified treatment for back pain in Danish primary care: A randomized controlled trial.

The ASKAP-EMU Early Science Project: 888 MHz radio continuum survey of the Large Magellanic Cloud (2021)
Journal Article
Pennock, C. M., Van Loon, J. T., Filipović, M. D., Andernach, H., Haberl, F., Kothes, R., …Vardoulaki, E. (2021). The ASKAP-EMU Early Science Project: 888 MHz radio continuum survey of the Large Magellanic Cloud. Monthly Notices of the Royal Astronomical Society, 506(3), 3540 - 3559. https://doi.org/10.1093/mnras/stab1858

We present an analysis of a new 120 deg2 radio continuum image of the Large Magellanic Cloud (LMC) at 888 MHz with a bandwidth of 288 MHz and beam size of 13${_{.}^{\prime\prime}}$9 × 12${_{.}^{\prime\prime}}$1 from the Australian Square Kilometre Ar... Read More about The ASKAP-EMU Early Science Project: 888 MHz radio continuum survey of the Large Magellanic Cloud.

Disrupting or reconfiguring racist narratives about Muslims? The representation of British Muslims during the Covid crisis (2021)
Journal Article
Poole, E., & Williamson, M. (2021). Disrupting or reconfiguring racist narratives about Muslims? The representation of British Muslims during the Covid crisis. Journalism, 24(2), https://doi.org/10.1177/14648849211030129

This article examines British newspaper coverage of Muslims during the first wave of the Coronavirus crisis. A well-established trajectory of research shows that Muslims are negativized in mainstream media representation in the UK. However, it became... Read More about Disrupting or reconfiguring racist narratives about Muslims? The representation of British Muslims during the Covid crisis.

The development and validation of a prognostic model to PREDICT Relapse of depression in adult patients in primary care: protocol for the PREDICTR study. (2021)
Journal Article
Chew-Graham. (2021). The development and validation of a prognostic model to PREDICT Relapse of depression in adult patients in primary care: protocol for the PREDICTR study. Diagnostic and Prognostic Research, 12 - ?. https://doi.org/10.1186/s41512-021-00101-x

BACKGROUND: Most patients who present with depression are treated in primary care by general practitioners (GPs). Relapse of depression is common (at least 50% of patients treated for depression will relapse after a single episode) and leads to consi... Read More about The development and validation of a prognostic model to PREDICT Relapse of depression in adult patients in primary care: protocol for the PREDICTR study..

A BACKWARDS-STEP FOR GILLICK: TRANS CHILDREN’S INABILITY TO CONSENT TO TREATMENT FOR GENDER DYSPHORIA – Quincy Bell & Mrs A v The Tavistock and Portman NHS Foundation Trust and Ors [2020] EWHC 3274 (Admin). (2021)
Journal Article
(2021). A BACKWARDS-STEP FOR GILLICK: TRANS CHILDREN’S INABILITY TO CONSENT TO TREATMENT FOR GENDER DYSPHORIA – Quincy Bell & Mrs A v The Tavistock and Portman NHS Foundation Trust and Ors [2020] EWHC 3274 (Admin). Medical Law Review, 699-715. https://doi.org/10.1093/medlaw/fwab020

The case of Quincy Bell & Mrs A v The Tavistock and Portman NHS Foundation Trust and Ors is a Judicial Review into the treatment practices of the Gender Identity Development Service (GIDS) run by Tavistock NHS Trust. The Divisional Court considered w... Read More about A BACKWARDS-STEP FOR GILLICK: TRANS CHILDREN’S INABILITY TO CONSENT TO TREATMENT FOR GENDER DYSPHORIA – Quincy Bell & Mrs A v The Tavistock and Portman NHS Foundation Trust and Ors [2020] EWHC 3274 (Admin)..

Impact of Chronic Kidney Disease on Revascularization and Outcomes in Patients with ST-Elevation Myocardial Infarction. (2021)
Journal Article
Mamas. (2021). Impact of Chronic Kidney Disease on Revascularization and Outcomes in Patients with ST-Elevation Myocardial Infarction. https://doi.org/10.1016/j.amjcard.2021.03.057

Chronic kidney disease (CKD) in patients with ST-elevation myocardial infarction (STEMI) is associated with worse outcomes. We assessed the impact of CKD on guideline directed coronary revascularization and outcomes among STEMI patients. The Nationwi... Read More about Impact of Chronic Kidney Disease on Revascularization and Outcomes in Patients with ST-Elevation Myocardial Infarction..

Safety and Efficacy of Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19 Population. (2021)
Journal Article
Sattar, Y., Mukuntharaj, P., Zghouzi, M., Suleiman, A. M., Attique, H., Ullah, W., …Alraies, M. C. (2021). Safety and Efficacy of Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19 Population. High Blood Pressure and Cardiovascular Prevention, 405 - 416. https://doi.org/10.1007/s40292-021-00462-w

INTRODUCTION: The safety of renin-angiotensin-aldosterone system inhibitors (RAASi) among COVID-19 patients has been controversial since the onset of the pandemic. METHODS: Digital databases were queried to study the safety of RAASi in COVID-19. The... Read More about Safety and Efficacy of Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19 Population..

Sex Differences in Outcomes Following Left Atrial Appendage Closure. (2021)
Journal Article
Sanjoy, S. S., Choi, Y., Sparrow, R. T., Baron, S. J., Abbott, J. D., Azzalini, L., …Bagur, R. (2021). Sex Differences in Outcomes Following Left Atrial Appendage Closure. https://doi.org/10.1016/j.mayocp.2020.11.031

OBJECTIVE: To evaluate the effects of female sex on in-hospital outcomes and to provide estimates for sex-specific prediction models of adverse outcomes following left atrial appendage closure (LAAC). PATIENTS AND METHODS: Cohort-based observational... Read More about Sex Differences in Outcomes Following Left Atrial Appendage Closure..

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK (2021)
Journal Article
Docherty, A. B., Mulholland, R. H., Lone, N. I., Cheyne, C. P., De Angelis, D., Diaz-Ordaz, K., …Investigators, I. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. Lancet Respiratory Medicine, 9(7), 773 - 785. https://doi.org/10.1016/s2213-2600%2821%2900175-2

Background Mortality rates in hospitalised patients with COVID-19 in the UK appeared to decline during the first wave of the pandemic. We aimed to quantify potential drivers of this change and identify groups of patients who remain at high risk of dy... Read More about Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK.

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study (2021)
Journal Article
Drake, T. M., Fairfield, C. J., Pius, R., Knight, S. R., Norman, L., Girvan, M., …Investigators, I. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study. The Lancet Rheumatology, 3(7), e498 - e506. https://doi.org/10.1016/s2665-9913%2821%2900104-1

Background Early in the pandemic it was suggested that pre-existing use of non-steroidal anti-inflammatory drugs (NSAIDs) could lead to increased disease severity in patients with COVID-19. NSAIDs are an important analgesic, particularly in those wit... Read More about Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study.

Peer mentorship to improve self-management of hip and knee osteoarthritis: a randomised feasibility trial (2021)
Journal Article
Anderson, A. M., Lavender, E. C., Dusabe-Richards, E., Mebrahtu, T. F., McGowan, L., Conaghan, P. G., …McHugh, G. A. (2021). Peer mentorship to improve self-management of hip and knee osteoarthritis: a randomised feasibility trial. BMJ Open, e045389 - e045389. https://doi.org/10.1136/bmjopen-2020-045389

Objective To determine the feasibility of conducting a randomised controlled trial (RCT) of a peer mentorship intervention to improve self-management of osteoarthritis (OA). Design Six-month parallel group non-blinded randomised feasibility trial.... Read More about Peer mentorship to improve self-management of hip and knee osteoarthritis: a randomised feasibility trial.

Men's reflections on their body image at different life stages: A thematic analysis of interview accounts from middle-aged men. (2021)
Journal Article
Malik, M., Grogan, S., Cole, J., & Gough, B. (2021). Men's reflections on their body image at different life stages: A thematic analysis of interview accounts from middle-aged men. Journal of Health Psychology, 1222 - 1232. https://doi.org/10.1177/1359105319871640

This study investigates how men's body image develops over time. A total of 14 men aged between 45 and 67?years completed in-depth interviews where they discussed their body image since childhood, prompted in some cases by photographs of themselves a... Read More about Men's reflections on their body image at different life stages: A thematic analysis of interview accounts from middle-aged men..

Rectal Hypersensitivity in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis (2021)
Journal Article
(2021). Rectal Hypersensitivity in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. Crohn's & Colitis 360, https://doi.org/10.1093/crocol/otab041

Abstract Abdominal pain is a key symptom of inflammatory bowel disease (IBD), particularly in active IBD, but also occurs in patients with quiescent disease suggesting that mechanisms other than active inflammation may be responsible. Putative hypoth... Read More about Rectal Hypersensitivity in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

15 Usability Recommendations for Delivering Clinical Guidelines on Mobile Devices (2021)
Conference Proceeding
Mitchell, J., De Quincey, E., Pantin, C., & Mustfa, N. (2021). 15 Usability Recommendations for Delivering Clinical Guidelines on Mobile Devices.

Local point of care clinical guidelines exist in numerous formats and cover a variety of clinical information, normally created on a national and local level. They are generally available as basic web pages, PDFs or documents. Despite widespread avai... Read More about 15 Usability Recommendations for Delivering Clinical Guidelines on Mobile Devices.

New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition. (2021)
Journal Article
Reynisson. (2021). New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition. Biomolecules, https://doi.org/10.3390/biom11070973

Usnic acid (UA) is a secondary metabolite of lichens that exhibits a wide range of biological activities. Previously, we found that UA derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1 (TDP1). It can remove covalent complex DNA-... Read More about New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition..

What Will It Mean for Me? Perceptions of the ECFMG 2023 Accreditation Requirement from an Online Forum (2021)
Journal Article
Arfeen, Z., Mughal, F., Ahmed Rashid, M., Smith, V., & Tackett, S. (2021). What Will It Mean for Me? Perceptions of the ECFMG 2023 Accreditation Requirement from an Online Forum. https://doi.org/10.30770/2572-1852-107.2.49

ABSTRACT In 2010, the Educational Commission for Foreign Medical Graduates (ECFMG) announced that as of 2023, physicians applying to train and practice in the United States will be required to graduate from a medical school that has been accredited u... Read More about What Will It Mean for Me? Perceptions of the ECFMG 2023 Accreditation Requirement from an Online Forum.

Prognostic biomarkers to identify patients likely to develop severe Crohn’s disease: a systematic review (2021)
Journal Article
Halligan, S., Boone, D., Archer, L., Ahmad, T., Bloom, S., Rodriguez-Justo, M., …Mallett, S. (2021). Prognostic biomarkers to identify patients likely to develop severe Crohn’s disease: a systematic review. Health Technology Assessment, 25(45), 1-66. https://doi.org/10.3310/hta25450

BACKGROUND: Identification of biomarkers that predict severe Crohn's disease is an urgent unmet research need, but existing research is piecemeal and haphazard. OBJECTIVE: To identify biomarkers that are potentially able to predict the development of... Read More about Prognostic biomarkers to identify patients likely to develop severe Crohn’s disease: a systematic review.