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Human Response to Plague: a Literary and Sociologic Perspective (2023)
Journal Article
Morelli, I., Maffulli, N., & Peretti, G. (2023). Human Response to Plague: a Literary and Sociologic Perspective. M.L.T.J. Muscles, Ligaments and Tendons Journal, 13(03), 436-439. https://doi.org/10.32098/mltj.03.2023.12

As COVID-19 pandemic, other plagues struck people in the past, provoking potential­ly dangerous social reactions in mankind. Luckily, these reactions are quite constant, even in different eras and cultures, and famous novelists accurately reported th... Read More about Human Response to Plague: a Literary and Sociologic Perspective.

Telemedicine and Orthopedic Surgery: A Narrative Review (2023)
Journal Article
Oliva, F., Bartoli, A., Sammaria, G., Oliva, G., & Maffulli, N. (in press). Telemedicine and Orthopedic Surgery: A Narrative Review. M.L.T.J. Muscles, Ligaments and Tendons Journal, 13(03), 353-359. https://doi.org/10.32098/mltj.03.2023.01

Purpose of review. The purpose of this paper is to review the current concepts regarding a new form of medicine which, especially in recent years, is enjoying more and more success. Especially how telemedicine can be beneficial in many areas of ortho... Read More about Telemedicine and Orthopedic Surgery: A Narrative Review.

Structures of factor XI and prekallikrein bound to domain 6 of high–molecular weight kininogen reveal alternate domain 6 conformations and exosites (2023)
Journal Article
Li, C., Barroeta, A. B., Wong, S. S., Kim, H. J., Pathak, M., Dreveny, I., …Emsley, J. (2023). Structures of factor XI and prekallikrein bound to domain 6 of high–molecular weight kininogen reveal alternate domain 6 conformations and exosites. Journal of Thrombosis and Haemostasis, 21(9), 2378-2389. https://doi.org/10.1016/j.jtha.2023.03.042

Background High–molecular weight kininogen (HK) circulates in plasma as a complex with zymogen prekallikrein (PK). HK is both a substrate and a cofactor for activated plasma kallikrein, and the principal exosite interactions occur between PK N-termi... Read More about Structures of factor XI and prekallikrein bound to domain 6 of high–molecular weight kininogen reveal alternate domain 6 conformations and exosites.

Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion (2023)
Journal Article
Holland, D., Fryer, A. A., Stedman, M., Hanna, F. W. F., Duff, C. J., Green, L., …Wu, P. (2023). Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion. Diabetes Therapy, https://doi.org/10.1007/s13300-023-01482-6

Women are on average diagnosed with diabetes mellitus at later age than men but have higher mortality. As the diagnosis of diabetes mellitus is primarily based on HbA1c, the use of a non-specific reference range and cut point for diabetes mellitus th... Read More about Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion.

Expedient, Affective, and Sustained Solidarities? Mediated Contestations of Islamophobia in the Case of Brexit, the Christchurch Terror Attack, and the COVID-19 Pandemic (2023)
Journal Article
Poole, E., Giraud, E. H., Richardson, J. E., & de Quincey, E. (2023). Expedient, Affective, and Sustained Solidarities? Mediated Contestations of Islamophobia in the Case of Brexit, the Christchurch Terror Attack, and the COVID-19 Pandemic. Social Media + Society, 9(3), 1-16. https://doi.org/10.1177/20563051231199452

This article advances research on mediated solidarity, by analyzing the contestation of Islamophobia on the social media platform Twitter, in the context of Brexit, the Christchurch terror attack, and the COVID-19 pandemic. Drawing on a unique longit... Read More about Expedient, Affective, and Sustained Solidarities? Mediated Contestations of Islamophobia in the Case of Brexit, the Christchurch Terror Attack, and the COVID-19 Pandemic.

Hope and exploitation in commercial provision of assisted reproductive technologies (2023)
Journal Article
Wrigley, A., Watts, G., Lipworth, W., & Newson, A. (2023). Hope and exploitation in commercial provision of assisted reproductive technologies. Hastings Center Report, 53(5), https://doi.org/10.1002/hast.1513

Innovation is a key driver of care provision in Assisted Reproductive Technologies (ART). ART providers offer a range of ‘add-on’ interventions, aiming to augment standard IVF protocols and improve the chances of a live birth. Particularly in the con... Read More about Hope and exploitation in commercial provision of assisted reproductive technologies.

Trade Unions in China: The Dynamics of Labour Relations and State-ancillary Unionism in Transition (2023)
Book Chapter
Brown, W., & Cao, X. (2023). Trade Unions in China: The Dynamics of Labour Relations and State-ancillary Unionism in Transition. In Routledge Handbook of Chinese Business and Management. Routledge. https://doi.org/10.4324/9780429448935-13

This chapter reviews the background and organisation of Chinese trade unions, their role in worker participation, rights protection and mobilisation, and their relationships with employers and the state. The analysis in the chapter reiterates the ess... Read More about Trade Unions in China: The Dynamics of Labour Relations and State-ancillary Unionism in Transition.

Regularized parametric survival modeling to improve risk prediction models (2023)
Journal Article
Hoogland, J., Debray, T., Crowther, M., Riley, R., IntHout, J., Reitsma, J., & Zwinderman, A. (2024). Regularized parametric survival modeling to improve risk prediction models. Biometrical Journal, 66(1), Article 2200319

We propose to combine the benefits of flexible parametric survival modeling and regularization to improve risk prediction modeling in the context of time-to-event data. Thereto, we introduce ridge, lasso, elastic net, and group lasso penalties for bo... Read More about Regularized parametric survival modeling to improve risk prediction models.

Skill Acquisition in Histology Education (2023)
Book Chapter
Door, R. (2023). Skill Acquisition in Histology Education. In L. Shapiro (Ed.), Microscopy Techniques for Biomedical Education and Healthcare Practice. Springer. https://doi.org/10.1007/978-3-031-36850-9_10

Histology has traditionally formed a key part of medical education. Increasing demands on the curriculum have resulted in a decline in time available for this complex topic. Previous research has identified that students struggle to apply their knowl... Read More about Skill Acquisition in Histology Education.

Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects that Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells (2023)
Journal Article
Pagani, I., Ottoboni, L., Panina-Bordignon, P., Martino, G., Poli, G., Taylor, S., …Vicenzi, E. (in press). Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects that Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells. Pharmaceuticals, 16(10), Article 1385. https://doi.org/10.3390/ph16101385

Zika virus (ZIKV) infection during pregnancy can result in severe birth defects, such as microcephaly, as well as a range of other related health complications. Heparin, a clinical-grade anticoagulant, is shown to protect neural progenitor cells from... Read More about Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects that Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells.

Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials (2023)
Journal Article
Krishnan, K., Campos, P. B., Nguyen, T. N., Tan, C. W., Chan, S. L., Appleton, J. P., …Bath, P. M. (in press). Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials. Frontiers in Stroke, 2, 1256664. https://doi.org/10.3389/fstro.2023.1256664

Acute intracerebral hemorrhage is the most devastating stroke subtype and is associated with significant morbidity and mortality. Poor prognosis is associated with primary brain injury from the presenting hematoma, and despite advances in clinical tr... Read More about Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials.

Demographic characteristics influencing the stem subsidence in total hip arthroplasty: an imaging study. (2023)
Journal Article
Migliorini, F., Maffulli, N., Pilone, M., Velaj, E., Hofmann, U. K., & Bell, A. (in press). Demographic characteristics influencing the stem subsidence in total hip arthroplasty: an imaging study. Archives of Orthopaedic and Trauma Surgery, https://doi.org/10.1007/s00402-023-05054-y

The present study evaluated whether patient demographic characteristics influence the subsidence of the stem in total hip arthroplasty (THA). The following characteristics were evaluated: age, height, weight, and sex. The association between the time... Read More about Demographic characteristics influencing the stem subsidence in total hip arthroplasty: an imaging study..

Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library † (2023)
Journal Article
Keenan, T., Hatton, N. E., Porter, J., Vendeville, J., Wheatley, D. E., Ghirardello, M., …Fascione, M. A. (in press). Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library †. Chemical Science, 14(42), 11638-11646. https://doi.org/10.1039/d3sc04169g

β-Mannosides are ubiquitous in nature, with diverse roles in many biological processes. Notably, Manβ1,4GlcNAc a constituent of the core N-glycan in eukaryotes was recently identified as an immune activator, highlighting its potential for use in immu... Read More about Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library †.

Prognosis of patients with neuropathic low back-related leg pain: An exploratory study using prospective data from UK primary care (2023)
Journal Article
Harrisson, S. A., Ogollah, R., Dunn, K. M., Foster, N. E., & Konstantinou, K. (2023). Prognosis of patients with neuropathic low back-related leg pain: An exploratory study using prospective data from UK primary care. Journal of Pain, 25(2), 533-544. https://doi.org/10.1016/j.jpain.2023.09.016

This prospective cohort study investigates the prognosis of patients with neuropathic low back-related leg pain (LBLP) consulting in UK primary care. Data from 511 patients were collected using standardised baseline clinical examinations (including M... Read More about Prognosis of patients with neuropathic low back-related leg pain: An exploratory study using prospective data from UK primary care.

Ligands containing 7-azaindole functionality for inner-sphere hydrogen bonding: structural and photophysical investigations (2023)
Journal Article
Coles, A., Wood, O., & Hawes, C. (2023). Ligands containing 7-azaindole functionality for inner-sphere hydrogen bonding: structural and photophysical investigations. Journal of the Serbian Chemical Society, 88(12), 1223-1236. https://doi.org/10.2298/jsc230623061c

The synthesis, structural analysis and spectroscopic characterisation of three new 7-azaindole ligands is reported, alongside a novel 7-azaindole derived coordination polymer, with the aim of identifying new bridging ligands containing inner-sphere h... Read More about Ligands containing 7-azaindole functionality for inner-sphere hydrogen bonding: structural and photophysical investigations.

Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study (2023)
Journal Article
Bishop, S., Narayanasamy, M. J., Paskins, Z., Corp, N., Bastounis, A., Griffin, J., …Sahota, O. (2023). Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study. BMC Musculoskeletal Disorders, 24(1), Article 770. https://doi.org/10.1186/s12891-023-06865-1

Background: Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly ta... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.

Evidence Based Practice: Medical Education Research (2023)
Book Chapter
Rees. (2023). Evidence Based Practice: Medical Education Research. In Family medicine in the undergraduate curriculum: preparing medical students to work in evolving health care systems. Taylor & Francis (Routledge)

Exploring the perspectives of community members on use of Nyaope in Tshwane, South Africa (2023)
Journal Article
Nzaumvila, D. K., Mash, R., & Helliwell, T. (in press). Exploring the perspectives of community members on use of Nyaope in Tshwane, South Africa. South African Family Practice, 65(1), https://doi.org/10.4102/safp.v65i1.5715

Background: Substance use is a major public health issue in South Africa. Cocktails, containing two or more low-quality substances, have been reported. Nyaope is one of the most popular and is widely available. It has a significant impact on users an... Read More about Exploring the perspectives of community members on use of Nyaope in Tshwane, South Africa.