All Outputs (60)

Tuning the properties of all natural polymeric scaffolds for tendon repair with cellulose microfibers (2024)
Journal Article

Rotator cuff injuries affect a large percentage of the population worldwide. Surgical repair has rates of failure of up to 70%, and existing materials used in the reinforcement of injuries often lack appropriate mechanical properties and biodegradabi... Read More about Tuning the properties of all natural polymeric scaffolds for tendon repair with cellulose microfibers.

TERT Promoter Methylation Is Oxygen-Sensitive and Regulates Telomerase Activity (2024)
Journal Article

Telomere repeats protect linear chromosomes from degradation, and telomerase has a prominent role in their maintenance. Telomerase has telomere-independent effects on cell proliferation, DNA replication, differentiation, and tumorigenesis. TERT (telo... Read More about TERT Promoter Methylation Is Oxygen-Sensitive and Regulates Telomerase Activity.

A ROLE FOR PERFUSION-DELIVERED SHEAR FORCE IN THE PROMOTION OF TPSC EV PRODUCTION (2024)
Conference Proceeding

Tendon injuries are a common problem that can significantly impact an individual's quality of life. While traditional surgical methods have been used to address this issue, Extracellular Vesicles (EVs) have emerged as a promising approach to promote... Read More about A ROLE FOR PERFUSION-DELIVERED SHEAR FORCE IN THE PROMOTION OF TPSC EV PRODUCTION.

Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration. (2023)
Journal Article

The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed significant challenges for healthcare practitioners, researchers, and individuals suffering from these conditions. Due to the absence of an approved treatmen... Read More about Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration..

Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential (2023)
Journal Article

Tendon injuries caused by overuse or age-related deterioration are frequent. Incomplete knowledge of somatic tendon cell biology and their progenitors has hindered interventions for the effective repair of injured tendons. Here, we sought to compare... Read More about Endotenon-Derived Type II Tendon Stem Cells Have Enhanced Proliferative and Tenogenic Potential.

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair (2023)
Journal Article

Tendons are dense connective tissues with a hierarchical polarized structure that respond to and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion and maintaining posture. Tendon injuries, also known as tendinopa... Read More about Tendon tissue engineering: An overview of biologics to promote tendon healing and repair.

Tendon stem cell populations have distinct proliferative and secretome profiles -a key role for physiological oxygen (2023)
Presentation / Conference

Growth Factor delivery through electrospun microfibres for tendon regeneration (2023)
Presentation / Conference

Fabrication of an injectable hydrogel with controllable in situ pore formation for the repair of chondral lesions (2023)
Presentation / Conference

A novel injectable hydrogel-based drug delivery system for the repair of cartilage defects (2023)
Presentation / Conference

Hypoxic conditions promote a proliferative, poorly differentiated phenotype in COPD lung tissue progenitor cells in vitro (2023)
Journal Article

PURPOSE: Chronic obstructive pulmonary disease (COPD) patients experience hypoxemia and lung tissue hypoxia, causing vasoconstriction, and at its most severe Cor pulmonale. However, minimal attention has been given to the effects of hypoxia at the ce... Read More about Hypoxic conditions promote a proliferative, poorly differentiated phenotype in COPD lung tissue progenitor cells in vitro.

Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent (2022)
Journal Article

The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) contains a variety of cytokines, with previous studies linking a changed secretome composition t... Read More about Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent.

Decellularised Pleural Membrane Patches In Pulmonary Regenerative Medicine (2022)
Conference Proceeding

Effect of bone marrow mesenchymal stem cells-derived exosomes on diabetes-induced retinal injury: Implication of Wnt/ b-catenin signaling pathway. (2022)
Journal Article

BACKGROUND: Diabetic retinopathy (DR) is a serious microvascular complication of diabetes mellitus. Mesenchymal stem cells are currently studied as therapeutic strategy for management of DR. Exosomes, considered as a promising cell-free therapy optio... Read More about Effect of bone marrow mesenchymal stem cells-derived exosomes on diabetes-induced retinal injury: Implication of Wnt/ b-catenin signaling pathway..

Stem cell-based therapy for human diseases. (2022)
Journal Article

Recent advancements in stem cell technology open a new door for patients suffering from diseases and disorders that have yet to be treated. Stem cell-based therapy, including human pluripotent stem cells (hPSCs) and multipotent mesenchymal stem cells... Read More about Stem cell-based therapy for human diseases..

TENOGENIC DIFFERENTIATION INDUCED BY COOPERATIVE GROWTH FACTORS (2022)
Presentation / Conference

IDENTIFICATION AND CHARACTERIZATION OF PORCINE-TENDON DERIVED STEM CELLS (TDSCS) (2022)
Presentation / Conference

DECELLULARISED PLEURAL MEMBRANES IN PULMONARY REGENERATIVE MEDICINE (2022)
Presentation / Conference

THE VOLATILOME OF HUMAN PLURIPOTENT STEM CELLS USING SELECTED ION FLOW TUBE MASS SPECTROMETRY (2022)
Presentation / Conference

EPITHELIAL-TO-MESENCHYMAL TRANSITION FOR STEMNESS CONTROL AND BIOENGINEERING STRATEGIES (2022)
Conference Proceeding