All Outputs (9)

Plasmodium falciparum GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA (2022)
Journal Article

In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have been identified and several are unique. Plasmodium telomeres, like those of most eukaryotes, contain guanine-rich repeats that can form G-quadruplex structures.... Read More about Plasmodium falciparum GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA.

Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen PlusTM, for protected cell therapy applications (2020)
Journal Article

High transplant cell loss is a major barrier to translation of stem cell therapy for pathologies of the brain and spinal cord. Encapsulated delivery of stem cells in biomaterials for cell therapy is gaining popularity but experimental research has ov... Read More about Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen PlusTM, for protected cell therapy applications.

Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study (2018)
Journal Article

Modification of metal surfaces with antimicrobial peptides is a promising approach to reduce bacterial adhesion. Here, cyclic peptides or cycloids, possessing remarkable stability and antimicrobial activities, were extracted and purified from Viola p... Read More about Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study.

A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells. (2018)
Journal Article

Corticosteroids (CSs) are widely used clinically, for example in pediatric respiratory distress syndrome, and immunosuppression to prevent rejection of stem cell transplant populations in neural cell therapy. However, such treatment can be associated... Read More about A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells..

Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer (2017)
Journal Article

Pre-clinical and retrospective studies of patients using statins to reduce plasma cholesterol have suggested that statins may be useful to treat cancer. However, prospective clinical trials have yet to demonstrate significant efficacy. We have previo... Read More about Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.

Flourescent liquid pyrene derivative-in-water mircoemulsions (2016)
Journal Article

A fluorescent liquid pyrene derivative with a high fluorescence quantum yield (65%) in the bulk state is reported. With this as the sole oil phase, stable luminescent oil-in-water microemulsions have been prepared. Increasing the loading of liquid py... Read More about Flourescent liquid pyrene derivative-in-water mircoemulsions.

Electron transfer dissociation of native peptides facilitates enhanced identification of urinary peptides (2015)
Journal Article

Urine as a biofluid is commonly used in clinical diagnostics, including those performed during pregnancy. Urine is a rich source of polypeptides and polypeptidic protein degradation products, which have been filtered from blood plasma, thus urine has... Read More about Electron transfer dissociation of native peptides facilitates enhanced identification of urinary peptides.

[203-POS]: Electron transfer dissociation for native peptide fragmentation facilitates enhanced identification of urinary peptides and proteins in pregnancy. (2015)
Journal Article

Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease.
Journal Article

Parkinson’s disease is a widespread condition caused by degeneration of dopamine neurons in the midbrain. A number of proteins are known to be important to signalling mechanisms present in the midbrain during natural dopamine neuron development, an... Read More about Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease..