All Outputs (1746)

Membership conditionality in an occupational community: Identity, inclusion and exclusion at Shelton Bar Steelworks (2025)
Thesis
Cottrell, H. W. (2025). Membership conditionality in an occupational community: Identity, inclusion and exclusion at Shelton Bar Steelworks. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279662

Previous literature has highlighted the emotional shelter offered by occupational identities and communities during periods of hardship, where community members draw upon fraternal camaraderie to raise solidarity. While this research explores this pr... Read More about Membership conditionality in an occupational community: Identity, inclusion and exclusion at Shelton Bar Steelworks.

Monitoring metabolism: improving the management of age related hearing loss using mass spectrometry and vibrational spectroscopy techniques (2025)
Thesis
Worrall, A. J. (2025). Monitoring metabolism: improving the management of age related hearing loss using mass spectrometry and vibrational spectroscopy techniques. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280024

Age-related hearing loss (ARHL) is the third most prevalent degenerative condition in the elderly, with cochlear fibrocyte inflammation preceding sensory cell loss. A deeper understanding of inflammatory mechanisms is essential for developing regener... Read More about Monitoring metabolism: improving the management of age related hearing loss using mass spectrometry and vibrational spectroscopy techniques.

Constraining the glacial history of the south-west Pennines: glacial landsystems, till geochemical signatures and ice-marginal positions (2025)
Thesis
Turner, A. C. (2025). Constraining the glacial history of the south-west Pennines: glacial landsystems, till geochemical signatures and ice-marginal positions. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280040

Palaeoglaciological reconstruction of the eastern sector of the Irish Sea Glacier, part of the Late Devensian British-Irish ice sheet, has been hampered due to a lack of natural exposures and depositional landforms which are used to determine the lim... Read More about Constraining the glacial history of the south-west Pennines: glacial landsystems, till geochemical signatures and ice-marginal positions.

Trade unionism for England’s classroom teachers: the individualcollective division of responses to New Public Management’s decollectivisation of industrial relations (2025)
Thesis
Whitmore, C. J. (2025). Trade unionism for England’s classroom teachers: the individualcollective division of responses to New Public Management’s decollectivisation of industrial relations. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1283900

This dissertation explores teacher unions’ responses to decollectivisation and disaggregation generated through New Public Management in England’s schools. The research took place in a densely unionised public sector context with competitive multiuni... Read More about Trade unionism for England’s classroom teachers: the individualcollective division of responses to New Public Management’s decollectivisation of industrial relations.

An investigation into the patellofemoral joint: improving diagnostics, prognostics and cell-based therapies (2025)
Thesis
Rix, L. D. (2025). An investigation into the patellofemoral joint: improving diagnostics, prognostics and cell-based therapies. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279827

Abnormalities in the patellofemoral joint (PFJ) may result in a change in the biomechanics of the joint, leading to patellofemoral pain (PFP), patellar instability, chondral lesions, and PFJ osteoarthritis (PFJ OA). This thesis aimed to further under... Read More about An investigation into the patellofemoral joint: improving diagnostics, prognostics and cell-based therapies.

Consciousness in film: adaptations of literary interiority (2025)
Thesis
Jánosdeák, Z. (2025). Consciousness in film: adaptations of literary interiority. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280085

This thesis explores cinematic ways in which consciousness is represented in film versions of selected novels. First, I focus on film adaptations of early twentieth-century novels: Joseph Strick’s Ulysses (1967), Sean Walsh’s Bloom (2003) and Marleen... Read More about Consciousness in film: adaptations of literary interiority.

Mobilities, migration and Covid-19 in Italy and the UK: qualitative comparative perspectives from two towns (2025)
Thesis
Fani, A. (2025). Mobilities, migration and Covid-19 in Italy and the UK: qualitative comparative perspectives from two towns. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279862

The outbreak of the COVID-19 virus and the subsequent declaration of a pandemic in March 2020 led to a period of fast-paced policy changes and shifting landscapes of risk and threat. In order to control the spreading of the virus, most democratic sta... Read More about Mobilities, migration and Covid-19 in Italy and the UK: qualitative comparative perspectives from two towns.

Scaling up mesenchymal stromal cell extracellular vesicle production for therapeutic application in rheumatoid arthritis (2025)
Thesis
Davies, R. L. (2025). Scaling up mesenchymal stromal cell extracellular vesicle production for therapeutic application in rheumatoid arthritis. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280129

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease. Given the complexity of RA and current treatment limitations, mesenchymal stromal cell extracellular vesicles (MSC EVs) have been proposed as an alternative. These small membrane-... Read More about Scaling up mesenchymal stromal cell extracellular vesicle production for therapeutic application in rheumatoid arthritis.

Biology, vectorial importance, and population genetics of Anopheles funestus sensu stricto and sibling species in Tanzania (2025)
Thesis
Mapua, S. A. (2025). Biology, vectorial importance, and population genetics of Anopheles funestus sensu stricto and sibling species in Tanzania. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1283908

Anopheles funestus group, and especially An. funestus sensu stricto, is a major driver of malaria transmission in eastern and Southern Africa due to its anthropophilic nature and insecticide resistance. Despite its importance, key biological characte... Read More about Biology, vectorial importance, and population genetics of Anopheles funestus sensu stricto and sibling species in Tanzania.

A study of innovation factors within the United Kingdom's freight transportation industry (2025)
Thesis
Lancaster, E. A. (2025). A study of innovation factors within the United Kingdom's freight transportation industry. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280051

This study explores the barriers and drivers of innovation in the freight transportation industry in the United Kingdom (UK). Research has yet to critically examine which innovation factors drive support for SMEs in achieving innovation in the UK fre... Read More about A study of innovation factors within the United Kingdom's freight transportation industry.

Investigating the biological activities of glycosaminoglycan mimetics against the Alzheimer’s associated proteins BACE1 and ApoE (2025)
Thesis
Pinter, E. A. M. (2025). Investigating the biological activities of glycosaminoglycan mimetics against the Alzheimer’s associated proteins BACE1 and ApoE. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279750

Alzheimer's disease (AD) is the most common form of dementia affecting approximately 44 million people worldwide. Current treatments are surrounded by limitations; cholinesterase inhibitors and memantine are not preventative and only mask symptoms, a... Read More about Investigating the biological activities of glycosaminoglycan mimetics against the Alzheimer’s associated proteins BACE1 and ApoE.

Poetic Inheritance: working-class women of the Liverpool-Irish diaspora and cultural and social hybridities (2025)
Thesis
Palmer, J. V. (2025). Poetic Inheritance: working-class women of the Liverpool-Irish diaspora and cultural and social hybridities. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279920

This thesis comprises both creative and critical work which investigates the cultural inheritance of working-class women in the Liverpool-Irish diaspora and translates the resultant discoveries into the creation of a poetry collection which is consci... Read More about Poetic Inheritance: working-class women of the Liverpool-Irish diaspora and cultural and social hybridities.

Novel insights into the role of long non-coding RNA MIAT in leukaemia (2025)
Thesis
Ostini, A. (2025). Novel insights into the role of long non-coding RNA MIAT in leukaemia. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280075

lncRNAs are key regulators of various cellular processes, playing significant roles in both healthy and malignant contexts, and actively contributing to carcinogenesis and cell fate determination. This study investigates the role of Myocardial Infarc... Read More about Novel insights into the role of long non-coding RNA MIAT in leukaemia.

Chemical Synthesis of S-linked Glycosaminoglycans (2025)
Thesis
O’Shea, C. (2025). Chemical Synthesis of S-linked Glycosaminoglycans. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280018

Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is ubiquitously distributed throughout the animal kingdom and represents a key regulator of biological processes. An example of a glycosami... Read More about Chemical Synthesis of S-linked Glycosaminoglycans.

An investigation into burnout in family physicians in low- and middle-income countries: a mixed methods study (2025)
Thesis
Wright, T. R. (2025). An investigation into burnout in family physicians in low- and middle-income countries: a mixed methods study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1279898

Background
Burnout is a work-related stress phenomenon, characterised by exhaustion and disengagement from work, and with significant consequences. Highly prevalent among healthcare professionals, burnout is becoming an issue of global concern. The... Read More about An investigation into burnout in family physicians in low- and middle-income countries: a mixed methods study.

Investigating the metabolic behaviour of human pluripotent stem cells in vitro using SIFT-MS and vibrational spectroscopy (2025)
Thesis
Barreto, S. N. (2025). Investigating the metabolic behaviour of human pluripotent stem cells in vitro using SIFT-MS and vibrational spectroscopy. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280122

Human pluripotent stem cells (hPSCs) have the potential to revolutionise regenerative medicine owing to their unlimited self-renewal capacity and ability to generate any cell type of the adult human body. Despite these features, several challenges ha... Read More about Investigating the metabolic behaviour of human pluripotent stem cells in vitro using SIFT-MS and vibrational spectroscopy.

Development and validation of a symptom assessment instrument for advanced chronic kidney disease (2025)
Thesis
Pugh-Clarke, K. (2025). Development and validation of a symptom assessment instrument for advanced chronic kidney disease. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280032

Background
Patients with advanced chronic kidney disease (CKD), not on renal replacement therapy (RRT), may have a significant symptom burden, which may negatively impact on health related quality of life (QoL). Accordingly, proactive symptom manag... Read More about Development and validation of a symptom assessment instrument for advanced chronic kidney disease.

Progressing a transformative critique; from necropolitics to abolition: migrant women, and third-sector resistance to no recourse to public funds (2025)
Thesis
Taha, S. H. (2025). Progressing a transformative critique; from necropolitics to abolition: migrant women, and third-sector resistance to no recourse to public funds. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280091

This interdisciplinary thesis examines the experiences of migrant women who have ‘No Recourse to Public Funds’ (NRPF). Empirical research was conducted working in partnership with a local organisation Staffordshire North & Stoke-on-Trent Citizens Adv... Read More about Progressing a transformative critique; from necropolitics to abolition: migrant women, and third-sector resistance to no recourse to public funds.

A socio-technical analysis of resource metabolism and factors influencing integrated circular economy approaches in manufacturing industries in Kenya (2025)
Thesis
Bowen, B. J. (2025). A socio-technical analysis of resource metabolism and factors influencing integrated circular economy approaches in manufacturing industries in Kenya. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1283916

Global attention to sustainability is currently focused on resource scarcity and environmental concerns such as climate change. Industries are a form of social system which transforms inputs into outputs to produce economic value; hence they have soc... Read More about A socio-technical analysis of resource metabolism and factors influencing integrated circular economy approaches in manufacturing industries in Kenya.

The original meaning of life: why objective thinking is the wrong tool for finding universal purpose (2025)
Thesis
Fox, J. (2025). The original meaning of life: why objective thinking is the wrong tool for finding universal purpose. (Thesis). Keele University. https://keele-repository.worktribe.com/output/1280110

In this thesis, I argue that metaphysical idealism provides a viable alternative to both the most popular kind of nihilism in the West and the belief that we can attain meaning in life without an ultimate meaning of life. I argue that there is a meta... Read More about The original meaning of life: why objective thinking is the wrong tool for finding universal purpose.