Outputs (2)

Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line (2018)
Journal Article
Haga, I. R., Simpson, J. L., Hawes, P. C., & Beard, P. M. (2018). Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line. Scientific Reports, 8, Article 16956. https://doi.org/10.1038/s41598-018-34732-w

The re-emergence of poxviral zoonotic infections and the threat of bioterrorism emphasise the demand for efective antipoxvirus therapies. Here, we show that carbenoxolone, a pharmacological inhibitor of gap junction function and a compound widely... Read More about Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line.

Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats (2018)
Journal Article
Beard. (2018). Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats. American journal of physiology. Gastrointestinal and liver physiology, G388 - G398. https://doi.org/10.1152/ajpgi.00343.2017

Signaling via the colony-stimulating factor 1 receptor (CSF1R) controls the survival, differentiation, and proliferation of macrophages. Mutations in CSF1 or CSF1R in mice and rats have pleiotropic effects on postnatal somatic growth. We tested the p... Read More about Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats.