Johannes Reynisson's Outputs (6)

THE KYNURENINE PATHWAY AND ITS ROLE IN GLIOBLASTOMA CELL MIGRATION (2023)
Presentation / Conference Contribution
Sirnikova, D., Reynisson, J., Brüning-Richardson, A., & Kirby, C. THE KYNURENINE PATHWAY AND ITS ROLE IN GLIOBLASTOMA CELL MIGRATION. Presented at BNOS Manchester 2023 Conference, Manchester, UK

AIMS The kynurenine (Kyn) pathway plays an important role in the pathogenesis of many cancers including glioblastomas (GBMs). The enzymes, indoleamine-2,3-dioxygenase (IDO1) and tryptophan-2,3-dioxygenase (TDO2), regulate the first and rate-limiting... Read More about THE KYNURENINE PATHWAY AND ITS ROLE IN GLIOBLASTOMA CELL MIGRATION.

Novel synthetic thienopyridine derivatives induce tubulin disruption and cell cycle (2020)
Presentation / Conference Contribution
Broughton, C., Edwards, K., Whitehead, K., Van Rensburg, M., Pilkington, L., Reynisson, J., Barker, D., & Dempsey-Hibbert, N. Novel synthetic thienopyridine derivatives induce tubulin disruption and cell cycle. Presented at 60th Annual Scientific Meeting of the British Society for Haematology (27–29 April 2020), Birmingham, UK

Synthesis of novel, potent phosphatidyl-choline specific phospholipase C inhibitors (2018)
Presentation / Conference Contribution
Pilkington, L., van Rensburg, M., Reynisson, J., Leung, E., Denny, W., & Barker, D. Synthesis of novel, potent phosphatidyl-choline specific phospholipase C inhibitors. Presented at 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond (AUG 19-23, 2018), Boston, MA, USA

Coumarin antifungal lead compounds, predicted mechanism of action (2017)
Presentation / Conference Contribution
Kingsford-Adaboh, R., Moscoh, D., & Reynisson, J. (2017, August). Coumarin antifungal lead compounds, predicted mechanism of action. Poster presented at XXIV IUCr Congress, Hyderabad International Convention Centre, Hyderabad, India

Introduction: Candida albicans is one of the most common causative fungi infection despite major efforts to control it. C. albicans has emerged as one of the main causes of morbidity and mortality in immunocompromised patients suffering from, e.g., c... Read More about Coumarin antifungal lead compounds, predicted mechanism of action.

Development and application of an NMR-based activity and inhibition assay for mycobacterial isocitrate lyase (2017)
Presentation / Conference Contribution
Bhusal, R., Patel, K., Kwai, B., Bashiri, G., Reynisson, J., Sperry, J., & Leung, I. Development and application of an NMR-based activity and inhibition assay for mycobacterial isocitrate lyase. Presented at 253rd National Meeting of the American-Chemical-Society (ACS) on Advanced Materials, Technologies, Systems, and Processes (APR 02-06, 2017), San Francisco, CA, USA

The effect of a phospholipase C gamma inhibitor on the proliferation and phenotype of Du145 prostate cancer cells (2014)
Presentation / Conference Contribution
Muzinic, N. R., Mastelic, A., Markotic, A., Culic, V. C., Ross, A., Vuica-Ross, M., Barker, D., & Reynisson, J. (2014, August). The effect of a phospholipase C gamma inhibitor on the proliferation and phenotype of Du145 prostate cancer cells. Poster presented at FEBS EMBO 2014 Conference, Paris, France

Introduction: Prostate cancer remains the second most common cause of cancer related death among men, highlighting the need for new therapies. Many cancer cellular functions have been dis-covered to be regulated by phospholipase C (PLC) gamma activat... Read More about The effect of a phospholipase C gamma inhibitor on the proliferation and phenotype of Du145 prostate cancer cells.