Outputs (4)

Synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer agents (2019)
Journal Article
Rosa Johnson-Ajinwo, O., Richardson, A., & Li, W. (2019). Synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer agents. Proceedings, 42. https://doi.org/10.3390/proceedings2019022042

Conference abstract, presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.

Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death (2019)
Journal Article
Abed, M., Khanim, F., Richardson, A., & Abdullah, M. (2019). Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death. Scientific reports, https://doi.org/10.1038/s41598-019-46102-1

The survival rate for patients with ovarian cancer has changed little in the past three decades since the introduction of platinum-based chemotherapy and new drugs are needed. Statins are drugs used for the treatment and prevention of cardiovascular... Read More about Screening a library of approved drugs reveals that prednisolone synergizes with pitavastatin to induce ovarian cancer cell death.

Isolation, identification and evaluation of anticancer compounds from unexplored Rutidea parviflora (2019)
Presentation / Conference
Li, W., Johnson-Ajinwo, O. . R., & Richardson, A. (2019, May). Isolation, identification and evaluation of anticancer compounds from unexplored Rutidea parviflora. Paper presented at Natural products in Drug Discovery and Human Health PSE Lisbon Meeting 2019

Palmatine from Unexplored Rutidea parviflora Showed Cytotoxicity and Induction of Apoptosis in Human Ovarian Cancer Cells (2019)
Journal Article
Li, W., Johnson-Ajinwo, O., & Richardson, A. (2019). Palmatine from Unexplored Rutidea parviflora Showed Cytotoxicity and Induction of Apoptosis in Human Ovarian Cancer Cells. Toxins, 237 - 237. https://doi.org/10.3390/toxins11040237

Ovarian cancer ranks amongst the deadliest cancers in the gynaecological category of cancers. This research work aims to evaluate in vitro anti-ovarian cancer activities and identify phytochemical constituents of a rarely explored plant speciesRutide... Read More about Palmatine from Unexplored Rutidea parviflora Showed Cytotoxicity and Induction of Apoptosis in Human Ovarian Cancer Cells.