Outputs (2)

A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials (2016)
Journal Article
Horrocks. (2016). A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials. Journal of Antimicrobial Chemotherapy, 717-726. https://doi.org/10.1093/jac/dkw449

Objectives: A future treatment for uncomplicated malaria will contain at least one component that exerts a rapid rate of kill. We describe here the validation and application of a simple, robust and rapid bioluminescence-based assay for the determina... Read More about A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials.

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond (2016)
Journal Article
Horrocks. (2016). Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLOS pathogens a peer-reviewed open-access journal published by the Public Library of Science, https://doi.org/10.1371/journal.ppat.1005763

A major cause of the paucity of new starting points for drug discovery is the lack of interaction between academia and industry. Much of the global resource in biology is present in universities, whereas the focus of medicinal chemistry is still larg... Read More about Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.