Outputs (2)

Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development. (2017)
Journal Article
Boyle, M. J., Skidmore, M., Dickerman, B., Cooper, L., Devlin, A., Yates, E., …Beeson, J. G. (2017). Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development. Antimicrobial Agents and Chemotherapy, 61(11), https://doi.org/10.1128/AAC.00709-17

Despite recent successful control efforts, malaria remains a leading global health burden. Alarmingly, resistance to current antimalarials is increasing, and the development of new drug families is needed to maintain malaria control. Current antimala... Read More about Identification of heparin modifications and polysaccharide inhibitors of Plasmodium falciparum merozoite invasion that have potential for novel drug development..

A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms (2017)
Journal Article
Aldulaimi, O., Uche a, F. I., Hameed, H., Mbye, H., Ullah, I., Drijfhout, F., …Li, W. (2017). A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms. Journal of Ethnopharmacology, 198, 221-225. https://doi.org/10.1016/j.jep.2017.01.014

Ethnopharmacological relevance and aim A decoction of the bark of Cylicodiscus gabunensis Harms is used as a traditional medicine in the treatment of malaria in Nigeria. This study aims to validate the antimalarial potency of this decoction in vitro... Read More about A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms.