Outputs (246)

A multi-professional survey of UK practice in the use of intra-articular corticosteroid injection for symptomatic first metatarsophalangeal joint osteoarthritis (2023)
Journal Article
Backhouse, M. R., Halstead, J., Roddy, E., Dhukaram, V., Chapman, A., Arnold, S., & Bruce, J. (in press). A multi-professional survey of UK practice in the use of intra-articular corticosteroid injection for symptomatic first metatarsophalangeal joint osteoarthritis. Journal of Foot and Ankle Research, 16(1), Article 71. https://doi.org/10.1186/s13047-023-00672-6

Background: The first metatarsophalangeal joint is the most common site of osteoarthritis (OA) in the foot and ankle. Intra-articular corticosteroid injections are widely used for this condition, but little is known about their use in practice. This... Read More about A multi-professional survey of UK practice in the use of intra-articular corticosteroid injection for symptomatic first metatarsophalangeal joint osteoarthritis.

Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink (2023)
Journal Article
Roddy, E., Bajpai, R., Forrester, H., James Partington, R., D Mallen, C., Clarson, L. E., Padmanabhan, N., Whittle, R., & Muller, S. (2023). Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, ard-2023-224154. https://doi.org/10.1136/ard-2023-224154

Objectives:
To determine the risk of adverse events associated with colchicine or non-steroidal anti-inflammatory drug (NSAID) prophylaxis when initiating allopurinol for gout.

Methods:
We conducted two matched retrospective cohort studies in... Read More about Safety of colchicine and NSAID prophylaxis when initiating urate-lowering therapy for gout: propensity score-matched cohort studies in the UK Clinical Practice Research Datalink.

Association of Bone Shape and Alignment Analyzed Using Statistical Shape Modeling With Severity of First Metatarsophalangeal Joint Osteoarthritis (2023)
Journal Article
Buldt, A. K., Gregory, J. S., Munteanu, S. E., Allan, J. J., Tan, J. M., Auhl, M., Landorf, K. B., Roddy, E., Marshall, M., & Menz, H. B. (2023). Association of Bone Shape and Alignment Analyzed Using Statistical Shape Modeling With Severity of First Metatarsophalangeal Joint Osteoarthritis. Arthritis Care & Research, https://doi.org/10.1002/acr.25237

Objective
We aimed to explore the relationship between bone shape and radiographic severity in individuals with first metatarsophalangeal joint osteoarthritis (first MTP joint OA).

Methods
Weightbearing lateral and dorsoplantar radiographs were... Read More about Association of Bone Shape and Alignment Analyzed Using Statistical Shape Modeling With Severity of First Metatarsophalangeal Joint Osteoarthritis.

Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study (2023)
Journal Article
Sokhal, B. S., Matetić, A., Abhishek, A., Banerjee, A., Partington, R., Roddy, E., Rashid, M., Mallen, C. D., & Mamas, M. A. (2023). Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study. American Journal of Cardiology, 206, 210-218. https://doi.org/10.1016/j.amjcard.2023.08.138

Data are limited on whether the causes of emergency department (ED) encounters for cardiovascular diseases (CVDs) and associated clinical outcomes vary by frailty status. Using the United States Nationwide ED Sample, selected CVD encounters (acute my... Read More about Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study.

Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY (2023)
Journal Article
Russell, M. D., Massey, J., Roddy, E., MacKenna, B., Bacon, S., Goldacre, B., Andrews, C. D., Hickman, G., Mehrkar, A., Mahto, A., Rutherford, A. I., Patel, S., Adas, M. A., Alveyn, E., Nagra, D., Bechman, K., Ledingham, J. M., Hudson, J., Norton, S., Cope, A. P., & Galloway, J. B. (2023). Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY. The Lancet Rheumatology, 5(10), e622-e632. https://doi.org/10.1016/S2665-9913%2823%2900206-0

Background
Gout is the most prevalent inflammatory arthritis, yet one of the worst managed. Our objective was to assess how the COVID-19 pandemic impacted incidence and quality of care for people with gout in England, UK.

Methods
With the approv... Read More about Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY.

Structural Foot Characteristics in People With Midfoot Osteoarthritis: Cross-Sectional Findings From the Clinical Assessment Study of the Foot (2023)
Journal Article
Lithgow, M. J., Buldt, A. K., Munteanu, S. E., Marshall, M. M., Thomas, M. J., Peat, G., Roddy, E., & Menz, H. B. (in press). Structural Foot Characteristics in People With Midfoot Osteoarthritis: Cross-Sectional Findings From the Clinical Assessment Study of the Foot. Arthritis Care & Research, 10.1002/acr.25217. https://doi.org/10.1002/acr.25217

To compare radiographic measures of foot structure between people with and without symptomatic radiographic midfoot osteoarthritis (OA). This was a cross-sectional study of adults aged ≥50 years registered with four UK general practices who reported... Read More about Structural Foot Characteristics in People With Midfoot Osteoarthritis: Cross-Sectional Findings From the Clinical Assessment Study of the Foot.

POS0508 A RANDOMISED CONTROLLED TRIAL COMPARING ANAKINRA VERSUS STEROIDS FOR THE TREATMENT OF GOUT ATTACKS IN PEOPLE WITH RENAL DISEASE (ASGARD): A FEASIBILITY STUDY (2023)
Presentation / Conference Contribution
Balasubramaniam, G., Almond, M., Harnett, P., Zhang, J., Turner, D., Scales, J., Moore, C., Hayden, K., Roddy, E., Mallen, C., Ng, N., Bhagat, S., Rutherford, A., & Dasgupta, B. (2023, May). POS0508 A RANDOMISED CONTROLLED TRIAL COMPARING ANAKINRA VERSUS STEROIDS FOR THE TREATMENT OF GOUT ATTACKS IN PEOPLE WITH RENAL DISEASE (ASGARD): A FEASIBILITY STUDY. Presented at EULAR 2023 European Congress of Rheumatology, Milan, Italy

Background Title: A study to determine the feasibility of undertaking a definitive randomised multi-centre, double-blind, double-dummy controlled study of Anakinra vs. intramuscular methylprednisolone acetate for ac... Read More about POS0508 A RANDOMISED CONTROLLED TRIAL COMPARING ANAKINRA VERSUS STEROIDS FOR THE TREATMENT OF GOUT ATTACKS IN PEOPLE WITH RENAL DISEASE (ASGARD): A FEASIBILITY STUDY.

P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study (2023)
Presentation / Conference Contribution
Padmanabhan, N., Muller, S., Bailey, J., Helliwell, T., Mackie, S. L., Mallen, C. D., & Roddy, E. (2023, April). P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Giant cell arteritis (GCA) is considered a medical emergency, and relapses are common, affecting around 50% of patients. Many of the early symptoms of GCA are non-specific and highly prevalent in older people, making the diagnosis challenging.

The... Read More about P203 Comparison of coding of giant cell arteritis in primary and secondary care records: an observational feasibility study.

P102 Barriers and facilitators to lifestyle change in people living with gout: a scoping review of qualitative studies (2023)
Presentation / Conference Contribution
Watson, L., Cornwall, N., Jinks, C., Bradbury, K., Goff, L., Little, P., Mallen, C. D., & Roddy, E. (2023, April). P102 Barriers and facilitators to lifestyle change in people living with gout: a scoping review of qualitative studies. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Background/Aims
Lifestyle, especially diet and alcohol, has been implicated in the causation of gout for centuries and the dietary factors which may trigger flares remain of great interest to people living with gout and their families. However, ther... Read More about P102 Barriers and facilitators to lifestyle change in people living with gout: a scoping review of qualitative studies.

BARRIERS AND FACILITATORS TO LIFESTYLE CHANGE IN PEOPLE LIVING WITH GOUT: A SCOPING REVIEW OF QUALITATIVE STUDIES (2023)
Presentation / Conference Contribution
Watson, L., Cornwall, N., Jinks, C., Bradbury, K., Goff, L., Little, P., Mallen, C. D., & Roddy, E. (2023, April). BARRIERS AND FACILITATORS TO LIFESTYLE CHANGE IN PEOPLE LIVING WITH GOUT: A SCOPING REVIEW OF QUALITATIVE STUDIES. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK