Outputs (42)

Healthcare use and its variation in people with fibromyalgia: a systematic review protocol (2025)
Journal Article
Katherine Byrne, A., Twohig, H., Muller, S., & C. Scott, I. (2025). Healthcare use and its variation in people with fibromyalgia: a systematic review protocol. Primary Health Care Research & Development, 26, 1-5. https://doi.org/10.1017/S1463423625000362

Aim:
A crucial step towards improving the care of people with fibromyalgia is understanding current practice. Our systematic review aims to address this by synthesising the global evidence around healthcare use in people with fibromyalgia, including... Read More about Healthcare use and its variation in people with fibromyalgia: a systematic review protocol.

A systematic review of the clinical effectiveness of dry powder inhalers in maintenance treatment and in treatment of acute exacerbations of asthma in children (2025)
Journal Article
Twohig, H., Franklin, L., Carroll, W., Corp, N., Jackson, E., Mallen, C., Ruan, B., Yapp, L., Van Der Windt, D., & Smith, J. (2025). A systematic review of the clinical effectiveness of dry powder inhalers in maintenance treatment and in treatment of acute exacerbations of asthma in children. Paediatric Respiratory Reviews, 1-37. https://doi.org/10.1016/j.prrv.2025.04.005

Background
Dry powder inhalers (DPIs) are a lower-carbon option than pressurised metered dose inhalers (pMDIs). However, DPIs require a forceful inhalation to achieve good lung deposition and there is uncertainty as to whether younger children can e... Read More about A systematic review of the clinical effectiveness of dry powder inhalers in maintenance treatment and in treatment of acute exacerbations of asthma in children.

Reducing pressurised metered dose inhaler prescriptions for asthma to reduce carbon emissions: a qualitative study of healthcare professional perspectives (2025)
Journal Article
Franklin, L., Mallen, C., & Twohig, H. (in press). Reducing pressurised metered dose inhaler prescriptions for asthma to reduce carbon emissions: a qualitative study of healthcare professional perspectives. British Journal of General Practice Open (BJGP Open), 1-17. https://doi.org/10.3399/BJGPO.2024.0208

Background
Prescribing of pressurised metered dose inhalers (pMDIs) is a key NHS carbon hotspot and reducing the number of these devices prescribed will help achieve NHS net zero targets.

Aim
To explore primary healthcare professionals’ perspe... Read More about Reducing pressurised metered dose inhaler prescriptions for asthma to reduce carbon emissions: a qualitative study of healthcare professional perspectives.

The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review (2025)
Journal Article
Cox, N., Farooq, S., Twohig, H., & Scott, I. C. (in press). The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review. Arthritis Care & Research, 1-32. https://doi.org/10.1002/acr.25532

As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co-morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression... Read More about The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review.

Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis (2025)
Journal Article
Nunes, A. R., Karaba, F., Geddes, O., Bickerton, A., Atherton, H., Dahlmann, F., Eccles, A., Gregg, M., Spencer, R., Twohig, H., & Dale, J. (2025). Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis. BMJ Open, 15(2), 1-9. https://doi.org/10.1136/bmjopen-2024-091404

Objectives: To summarise and synthesise existing literature on the implementation of decarbonisation actions in general practice, to outline the actions being implemented, factors influencing decarbonisation, identify evidence gaps and questions for... Read More about Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis.

30-day Unplanned Readmission Rates and Causes in Patients Hospitalized for Acute Coronary Syndrome Based on DANish CoMorbidity Index for Acute Myocardial Infarction Score. (2025)
Journal Article
Sokhal, B. S., Matetić, A., Marshall, M., Twohig, H., Shepherd, T., Mallen, C. D., & Mamas, M. A. (2025). 30-day Unplanned Readmission Rates and Causes in Patients Hospitalized for Acute Coronary Syndrome Based on DANish CoMorbidity Index for Acute Myocardial Infarction Score. Hellenic Journal of Cardiology, https://doi.org/10.1016/j.hjc.2025.01.006

Introduction
This study aimed to investigate the association of the DANish CoMorbidity Index for Acute Myocardial Infarction (DANCAMI) score with 30-day unplanned readmission rates and causes in patients with acut... Read More about 30-day Unplanned Readmission Rates and Causes in Patients Hospitalized for Acute Coronary Syndrome Based on DANish CoMorbidity Index for Acute Myocardial Infarction Score..

Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review] (2024)
Journal Article
Raquel Nunes, A., Atherton, H., Dahlmann, F., Eccles, A., Geddes, O., Gregg, M., Jowett, S., Karaba, F., Nelson, L., Spencer, R., Twohig, H., & Dale, J. (2024). Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review]. NIHR Open Research, 1-11. https://doi.org/10.3310/nihropenres.13833.1

Introduction
The urgency to address climate change and reduce carbon emissions in healthcare, highlighted in the United Kingdom (UK) by the 'Delivering a 'Net Zero' National Health Service (NHS)' report, emphasises the need for healthcare organisati... Read More about Supporting the drive for net zero by decarbonising general practice – A longitudinal study protocol [version 1; peer review: awaiting peer review].

Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum (2024)
Journal Article
Scott, I. C., Daud, N., Bailey, J., Twohig, H., Hider, S. L., Mallen, C. D., Jordan, K. P., & Muller, S. (2024). Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum. BMC Medicine, 22(1), 575. https://doi.org/10.1186/s12916-024-03774-5

Background: Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associated with... Read More about Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum.

Optimising inhaled therapy for patients with asthma. (2024)
Journal Article
Bansal, A., Franklin, L., & Twohig, H. (in press). Optimising inhaled therapy for patients with asthma. BMJ, 386, 1-6. https://doi.org/10.1136/bmj-2024-080353

What you need to know
Sub-optimally controlled asthma is common, in part because of normalisation of symptoms, underuse of preventer therapy, overuse of reliever therapy, and poor inhaler technique. Ensuring patients are using the right inhaled medi... Read More about Optimising inhaled therapy for patients with asthma..

Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis protocol (2024)
Journal Article
Karaba, F., Raquel Nunes, A., Geddes, O., O, G., Atherton, H., Dahlmann, F., F, D., Eccles, A., A, E., Gregg, M., M, G., Spencer, R., Twohig, H., H, T., & Dale, J. (2024). Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis protocol. BMJ Open, 14(9), https://doi.org/10.1136/bmjopen-2024-087795

Introduction: There is growing recognition of the importance of primary care in addressing climate change. The World Organisation of Family Doctors has urged general practitioners worldwide to commit to tackling climate change and to serve as agents... Read More about Implementation of decarbonisation actions in general practice: a systematic review and narrative synthesis protocol.