Outputs (39)

Healthcare use and its variation in people with fibromyalgia: a systematic review protocol (2025)
Journal Article
Katherine Byrne, A., Twohig, H., Muller, S., & C. Scott, I. (2025). Healthcare use and its variation in people with fibromyalgia: a systematic review protocol. Primary Health Care Research & Development, 26, 1-5. https://doi.org/10.1017/S1463423625000362

Aim:
A crucial step towards improving the care of people with fibromyalgia is understanding current practice. Our systematic review aims to address this by synthesising the global evidence around healthcare use in people with fibromyalgia, including... Read More about Healthcare use and its variation in people with fibromyalgia: a systematic review protocol.

The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review (2025)
Journal Article
Cox, N., Farooq, S., Twohig, H., & Scott, I. C. (in press). The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review. Arthritis Care & Research, 1-32. https://doi.org/10.1002/acr.25532

As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co-morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression... Read More about The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review.

Pharmacological pain management in patients with rheumatoid arthritis: a narrative literature review (2025)
Journal Article
Cox, N., Mallen, C. D., & Scott, I. C. (2025). Pharmacological pain management in patients with rheumatoid arthritis: a narrative literature review. BMC Medicine, 23(1), Article 54. https://doi.org/10.1186/s12916-025-03870-0

Background: Pain is a major challenge for patients with rheumatoid arthritis (RA), with many people suffering chronic pain. Current RA management guidelines focus on assessing and reducing disease activity using disease-modifying anti-rheumatic drugs... Read More about Pharmacological pain management in patients with rheumatoid arthritis: a narrative literature review.

Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals (2025)
Journal Article
Chaplin, H., Simpson, C., Wilkins, K., Meehan, J., Ng, N., Galloway, J., Scott, I. C., Sen, D., Tattersall, R., Moss‐Morris, R., Lempp, H., & Norton, S. (2025). Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals. British Journal of Health Psychology, 30(1), Article e12780. https://doi.org/10.1111/bjhp.12780

Objectives: This study aims to explore patients' and clinicians' understanding and experiences of refractory disease (RD) and persistent physical and emotional symptoms (PPES) in patients with inflammatory arthritis (IA), namely rheumatoid arthritis... Read More about Characteristics of refractory disease and persistent symptoms in inflammatory arthritis: Qualitative framework analysis of interviews with patients and health care professionals.

Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum (2024)
Journal Article
Scott, I. C., Daud, N., Bailey, J., Twohig, H., Hider, S. L., Mallen, C. D., Jordan, K. P., & Muller, S. (2024). Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum. BMC Medicine, 22(1), 575. https://doi.org/10.1186/s12916-024-03774-5

Background: Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associated with... Read More about Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum.

Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope (2024)
Journal Article
Scott, I. C., Babatunde, O., Barker, C., Beesley, R., Beesley, R., Birkinshaw, H., Brooke, M., Chaplin, H., Chapman, L., Ciurtin, C., Dale, J., Dockrell, D., Dures, E., Harrison, K., Jani, M., Lee, C., McCarron, M., Mallen, C. D., O’Connor, A., Pidgeon, C., …Shenker, N. G. (in press). Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(4), Article rkae128. https://doi.org/10.1093/rap/rkae128

Lay Summary: What does this mean for patients? Inflammatory arthritis includes conditions causing swollen and painful joints. The main types are rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and juvenile idiopathic arthritis. It... Read More about Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope.

Genome-wide Association of Rheumatoid Arthritis in the African Ancestry Identifies HLA Amino Acid Polymorphisms of Risk (2024)
Presentation / Conference Contribution
Zhang, H., Sakaue, . S., Posner, D., Cui, . J., Yang, D., Budu-Aggrey, A., Ho, Y.-L., Costa, L., Matty, R., Huang, S., Monach, P., Ishaigaki, K., Maripuri, M., Melley, C., Tanukonda, V., Sangar, R., McDermott, G., Jeffway, M., Laufer, V., Okada, Y., … Liao, K. Genome-wide Association of Rheumatoid Arthritis in the African Ancestry Identifies HLA Amino Acid Polymorphisms of Risk. Presented at ACR Convergence 2024, Washington DC

Background/Purpose: The association between RA and the MHC is largely explained by five amino acid (AA) positions: DRB1 positions 11, 13, 71, and 74, HLA-B position 9, and DPB1 position 9. However, these prior studies are from populations genetically... Read More about Genome-wide Association of Rheumatoid Arthritis in the African Ancestry Identifies HLA Amino Acid Polymorphisms of Risk.

Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data (2024)
Journal Article
Akthar, M., Mason, K. J., & Scott, I. C. (2024). Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data. Musculoskeletal Care, 22(3), Article e1916. https://doi.org/10.1002/msc.1916

Objective: The Internet has transformed how patients access health information. We examined Google search engine data to understand which aspects of health are most often searched for in combination with inflammatory arthritis (IA). Methods: Using Go... Read More about Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data.

The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica (2024)
Journal Article
Scott, I. C., Bajpai, R., Hider, S. L., Helliwell, T., Mallen, C. D., & Muller, S. (in press). The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica. Rheumatology Advances in Practice, 8(3), Article rkae081. https://doi.org/10.1093/rap/rkae081

Objective
To examine the association between obesity and patient-reported outcomes measures (PROMs) in a primary care-based cohort of people with polymyalgia rheumatica (PMR).

Methods
The PMR Cohort Study recruited people with incident PMR from... Read More about The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica.

AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM (2024)
Presentation / Conference Contribution
Scott, I., Daud, N., Bailey, J., Twohig, H., Hider, S., Mallen, C., Jordan, K., & Muller, S. AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM. Presented at EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria, Vienna

Background: Recent observational studies suggest gabapentinoids associate with an increased risk of fractures. The potential for confounding inherent to non-randomised studies of interventions, however, alongside th... Read More about AB0228 GABAPENTINOID USE AND THE RISK OF FRACTURES IN PEOPLE WITH INFLAMMATORY ARTHRITIS: NESTED CASE-CONTROL STUDY IN THE CLINICAL PRACTICE RESEARCH DATALINK (CPRD) AURUM.