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The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study (2025)
Journal Article
Allison, K., Nelligan, R. K., Lawford, B., Jones, S. E., Hinman, R. S., Pardo, J., Quicke, J. G., Sumithran, P., Prendergast, J., George, E. S., Holden, M. A., Foster, N. E., & Bennell, K. L. (in press). The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study. Brazilian Journal of Physical Therapy, 29(2), 1-8. https://doi.org/10.1016/j.bjpt.2025.101172

Background
Exercise and weight loss are core treatments for knee osteoarthritis (OA). While physical therapists are considered well placed to engage in weight management alongside exercise (not replacing dietician care), evidence surrounding physica... Read More about The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study.

Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study (2024)
Journal Article
Bullock, L., Holden, M. A., Jinks, C., Atiah Asamane, E., Herron, D., Borrelli, B., Callaghan, M. J., Birrell, F., Halliday, N., Marshall, M., Sowden, G., Ingram, C., McBeth, J., Dziedzic, K., Foster, N. E., Jowett, S., Lawton, S., Mallen, C. D., & Peat, G. (2024). Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study. Musculoskeletal Care, 22(4), Article e70021. https://doi.org/10.1002/msc.70021

Objectives: To explore physiotherapists' experiences and perceived acceptability of delivering a bracing intervention for knee osteoarthritis (OA) in the ‘PROvision of braces for Patients with knee OA’ (PROP OA) randomised controlled trial. Method: S... Read More about Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study.

Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome (2024)
Journal Article
Hattle, M., Ensor, J., Scandrett, K., van Middelkoop, M., van der Windt, D. A., Holden, M. A., & Riley, R. D. (2024). Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1750

Individual participant data (IPD) meta‐analysis projects obtain, harmonise, and synthesise original data from multiple studies. Many IPD meta‐analyses of randomised trials are initiated to identify treatment effect modifiers at the individual level,... Read More about Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome.

Knee braces for knee osteoarthritis: A scoping review and narrative synthesis of interventions in randomised controlled trials (2024)
Journal Article
Holden, M. A., Murphy, M., Simkins, J., Thomas, M. J., Huckfield, L., Quicke, J. G., Halliday, N., Birrell, F. N., Borrelli, B., Callaghan, M. J., Dziedzic, K., Felson, D., Foster, N. E., Ingram, C., Jinks, C., Jowett, S., Nicholls, E., & Peat, G. (2024). Knee braces for knee osteoarthritis: A scoping review and narrative synthesis of interventions in randomised controlled trials. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.08.010

Objective
To identify and synthesise the content of knee bracing interventions in randomised controlled trials (RCTs) of knee osteoarthritis (OA).

Design
In this scoping review, three electronic databases (PubMed, Web of Science, Cochrane) were... Read More about Knee braces for knee osteoarthritis: A scoping review and narrative synthesis of interventions in randomised controlled trials.

People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank. (2024)
Journal Article
van Middelkoop, M., Schiphof, D., Middelkoop M, V., Hattle, M., D, S., Simkins, J., M, H., Bennell, K. L., J, S., Hinman, R. S., KL, B., Allen, K. D., RS, H., Knoop, J., KD, A., van Baar, M. E., J, K., Bossen, D., Baar ME, V., Wallis, J., …SMA, B.-Z. (2024). People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.07.007

To investigate whether duration of knee symptoms influenced the magnitude of the effect of exercise therapy compared to non-exercise control interventions on pain and physical function in people with knee osteoarthritis (OA). We undertook an individu... Read More about People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank..

Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. (2024)
Journal Article
Lawford, B. J., Allison, K., Nelligan, R., Campbell, P., Hinman, R. S., Jones, S. E., Pardo, J., Quicke, J. G., Sumithran, P., Prendergast, J., George, E. S., Holden, M. A., Foster, N. E., & Bennell, K. L. (2024). Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. Arthritis Care & Research, https://doi.org/10.1002/acr.25401

Explore the experiences of people with knee osteoarthritis who received a very low energy diet (VLED) and exercise program from a physiotherapist. Mixed methods study involving questionnaires (n=42) and semi-structured interviews (n=22) with randomiz... Read More about Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study..

269 CLINICAL GUIDELINE RESEARCH RECOMMENDATIONS FOR THE NON-SURGICAL MANAGEMENT OF OSTEOARTHRITIS: A THEMATIC SYNTHESIS. (2024)
Presentation / Conference Contribution
Woodcock, C., English, E., Jinks, C., Healey, E. L., Parry, E., Paskins, Z., Roddy, E., Simkins, J., Thomas, M., Bennell, K., Hinman, R. S., & Holden, M. (2024, April). 269 CLINICAL GUIDELINE RESEARCH RECOMMENDATIONS FOR THE NON-SURGICAL MANAGEMENT OF OSTEOARTHRITIS: A THEMATIC SYNTHESIS. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

767 EXPLORING THE POTENTIAL EXTENDED ROLE OF COMMUNITY PHARMACY IN THE MANAGEMENT OF OSTEOARTHRITIS: SURVEYS AND INTERVIEWS WITH COMMUNITY PHARMACY STAFF AND OTHER HEALTHCARE PROFESSIONALS (2024)
Presentation / Conference Contribution
Simkins, J., Holden, M., Babatunde, O. O., White, S., Nicholls, E., Long, A., Dziedzic, K. S., Chudyk, A., Todd, A., Walker, C., Stanford, C., Cottrell, E., Edwards, J., Healey, E. L., Cork, T., Mallen, C., & O'Brien, N. (2024, April). 767 EXPLORING THE POTENTIAL EXTENDED ROLE OF COMMUNITY PHARMACY IN THE MANAGEMENT OF OSTEOARTHRITIS: SURVEYS AND INTERVIEWS WITH COMMUNITY PHARMACY STAFF AND OTHER HEALTHCARE PROFESSIONALS. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

783 FEASIBILITY OF A COMORBIDITY-TAILORED EXERCISE AND EDUCATION INTERVENTION FOR PEOPLE AGED 80 YEARS OR OLDER WITH HIP OR KNEE OSTEOARTHRITIS. (2024)
Presentation / Conference
Nicolson, P., Holden, M., Marian, I., Saeedi, E., Williamson, E., Hopewell, S., & Lamb, S. (2024, April). 783 FEASIBILITY OF A COMORBIDITY-TAILORED EXERCISE AND EDUCATION INTERVENTION FOR PEOPLE AGED 80 YEARS OR OLDER WITH HIP OR KNEE OSTEOARTHRITIS. Poster presented at 24 OARSI World Congress on Osteoarthritis, Vienna, Austria