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Outputs (96)

Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial (2025)
Other
Thomas, M. J., Hughes, G., Cooke, K., Butler-Walley, S., Marshall, E., Bowyer, L., Wathall, S., Smith, J., Lawton, S. A., Brammar, J., Burnett, T., Drake, C., Foster, N. E., Hendry, G. J., Holden, M. A., Jaki, T., Joseph, R., Keenan, A.-M., Kigozi, J., Lewis, M., …Roddy, E. (2025). Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial

Background
Plantar heel pain (PHP) is the most common soft tissue foot condition and impairs mobility, physical function, ability to work, and quality of life. Systematic reviews highlight a need for high-quality randomised controlled trials (RCTs)... Read More about Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial.

704 The effect of exercise therapy on psychological factors among individuals with knee or hip osteoarthritis; a systematic review and meta-analysis (2025)
Presentation / Conference Contribution
Pouwels, S., der Leeden, M. V., Snoeker, B., Holden, M., & Runhaar, J. (2025, April). 704 The effect of exercise therapy on psychological factors among individuals with knee or hip osteoarthritis; a systematic review and meta-analysis. Presented at 2025 OARSI World Congress on Osteoarthritis, Incheon, South Korea

The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study (2025)
Journal Article
Allison, K., Nelligan, R. K., Lawford, B., Jones, S. E., Hinman, R. S., Pardo, J., Quicke, J. G., Sumithran, P., Prendergast, J., George, E. S., Holden, M. A., Foster, N. E., & Bennell, K. L. (in press). The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study. Brazilian Journal of Physical Therapy, 29(2), 1-8. https://doi.org/10.1016/j.bjpt.2025.101172

Background
Exercise and weight loss are core treatments for knee osteoarthritis (OA). While physical therapists are considered well placed to engage in weight management alongside exercise (not replacing dietician care), evidence surrounding physica... Read More about The experiences of physical therapists delivering a very low energy diet and exercise intervention for weight loss in people with knee osteoarthritis: A qualitative study.

Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study (2024)
Journal Article
Bullock, L., Holden, M. A., Jinks, C., Atiah Asamane, E., Herron, D., Borrelli, B., Callaghan, M. J., Birrell, F., Halliday, N., Marshall, M., Sowden, G., Ingram, C., McBeth, J., Dziedzic, K., Foster, N. E., Jowett, S., Lawton, S., Mallen, C. D., & Peat, G. (2024). Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study. Musculoskeletal Care, 22(4), Article e70021. https://doi.org/10.1002/msc.70021

Objectives: To explore physiotherapists' experiences and perceived acceptability of delivering a bracing intervention for knee osteoarthritis (OA) in the ‘PROvision of braces for Patients with knee OA’ (PROP OA) randomised controlled trial. Method: S... Read More about Physiotherapists' Experiences and Perceived Acceptability of Delivering a Knee Bracing Intervention for People With Symptomatic Knee Osteoarthritis in a Randomised Trial (PROP OA): A Qualitative Study.

Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome (2024)
Journal Article
Hattle, M., Ensor, J., Scandrett, K., van Middelkoop, M., van der Windt, D. A., Holden, M. A., & Riley, R. D. (2024). Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome. Research Synthesis Methods, https://doi.org/10.1002/jrsm.1750

Individual participant data (IPD) meta‐analysis projects obtain, harmonise, and synthesise original data from multiple studies. Many IPD meta‐analyses of randomised trials are initiated to identify treatment effect modifiers at the individual level,... Read More about Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome.

Knee braces for knee osteoarthritis: A scoping review and narrative synthesis of interventions in randomised controlled trials (2024)
Journal Article
Holden, M. A., Murphy, M., Simkins, J., Thomas, M. J., Huckfield, L., Quicke, J. G., Halliday, N., Birrell, F. N., Borrelli, B., Callaghan, M. J., Dziedzic, K., Felson, D., Foster, N. E., Ingram, C., Jinks, C., Jowett, S., Nicholls, E., & Peat, G. (2024). Knee braces for knee osteoarthritis: A scoping review and narrative synthesis of interventions in randomised controlled trials. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.08.010

Objective
To identify and synthesise the content of knee bracing interventions in randomised controlled trials (RCTs) of knee osteoarthritis (OA).

Design
In this scoping review, three electronic databases (PubMed, Web of Science, Cochrane) were... Read More about Knee braces for knee osteoarthritis: A scoping review and narrative synthesis of interventions in randomised controlled trials.

People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank. (2024)
Journal Article
van Middelkoop, M., Schiphof, D., Middelkoop M, V., Hattle, M., D, S., Simkins, J., M, H., Bennell, K. L., J, S., Hinman, R. S., KL, B., Allen, K. D., RS, H., Knoop, J., KD, A., van Baar, M. E., J, K., Bossen, D., Baar ME, V., Wallis, J., …SMA, B.-Z. (2024). People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2024.07.007

To investigate whether duration of knee symptoms influenced the magnitude of the effect of exercise therapy compared to non-exercise control interventions on pain and physical function in people with knee osteoarthritis (OA). We undertook an individu... Read More about People with short symptom duration of knee osteoarthritis benefit more from exercise therapy than people with longer symptom duration: An individual participant data meta-analysis from the OA trial bank..

Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. (2024)
Journal Article
Lawford, B. J., Allison, K., Nelligan, R., Campbell, P., Hinman, R. S., Jones, S. E., Pardo, J., Quicke, J. G., Sumithran, P., Prendergast, J., George, E. S., Holden, M. A., Foster, N. E., & Bennell, K. L. (2024). Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study. Arthritis Care & Research, https://doi.org/10.1002/acr.25401

Explore the experiences of people with knee osteoarthritis who received a very low energy diet (VLED) and exercise program from a physiotherapist. Mixed methods study involving questionnaires (n=42) and semi-structured interviews (n=22) with randomiz... Read More about Exploring Experiences of People With Knee Osteoarthritis Who Received a Physiotherapist-Delivered Dietary Weight Loss and Exercise Intervention: A Mixed Methods Study..

768 STAKEHOLDER CO-DESIGN OF AN EXTENDED COMMUNITY PHARMACY ROLE AND SERVICE DELIVERY MODEL FOR PROVIDING OSTEOARTHRITS CARE: THE PHARMOA MODEL (2024)
Presentation / Conference Contribution
Holden, M., Stanford, C., Simkins, J., Babatunde, O. O., White, S., O'Brien, N., Chudyk, A., Dziedzic, K. S., Todd, A., Long, A., Walker, C., Cork, T., Cottrell, E., Edwards, J., Nicholls, E., Mallen, C., & Healey, E. L. (2024, April). 768 STAKEHOLDER CO-DESIGN OF AN EXTENDED COMMUNITY PHARMACY ROLE AND SERVICE DELIVERY MODEL FOR PROVIDING OSTEOARTHRITS CARE: THE PHARMOA MODEL. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria