Outputs (72)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer (2025)
Journal Article
Chen, L., Wang, C., Chang, J., Shiau, A., Shieh, G., Tseng, Y., Yen, Y., Huang, T., Cheng, L., Wu, Y., Wu, C., Su, B., & Wu, P. (2025). Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer. Molecular Oncology, 1-20. https://doi.org/10.1002/1878-0261.70035

Elevated expression of prothymosin α (ProT) is frequently observed in cancers, but the underlying molecular mechanism remains poorly understood. Here, we report the clinical relevance of ProT expression and its correlation with lung cancer progressio... Read More about Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer.

Impact of Covid-19 on antenatal care: evidence from Madagascar Demographic and Health Survey (2025)
Journal Article
Magadi, M. A., Obare, F. O., Kaseje, N., & Wu, P. (in press). Impact of Covid-19 on antenatal care: evidence from Madagascar Demographic and Health Survey. Journal of Biosocial Science, 1-19. https://doi.org/10.1017/S0021932025000112

Despite the growing literature on the impact of Covid-19 on antenatal care (ANC) and maternal/neonatal and child health outcomes globally, substantial knowledge gaps remain about the population-level impact in sub-Saharan Africa (SSA). Existing evide... Read More about Impact of Covid-19 on antenatal care: evidence from Madagascar Demographic and Health Survey.

Maternal perinatal anxiety and infant primary care use in 1998–2016: a UK cohort study (2025)
Journal Article
Smith, H. C., Archer, C., Bailey, J., Chew Graham, C., Evans, J., Fisher, T., Kessler, D., Kingstone, T., Procter, J., Shivji, N., Silverwood, V., Spruce, A., Turner, K., Wu, P., Yu, D., & Petersen, I. (2025). Maternal perinatal anxiety and infant primary care use in 1998–2016: a UK cohort study. BMJ Mental Health, 28(1), 1-8. https://doi.org/10.1136/bmjment-2024-301160

There is some evidence that perinatal anxiety (PNA) is associated with lower rates of infant vaccinations and decreased access to preventative infant healthcare, but results across studies have not been conclusive. To investigate the relationship bet... Read More about Maternal perinatal anxiety and infant primary care use in 1998–2016: a UK cohort study.

The Impact of Age and Sex on Fasting Plasma Glucose and Glycated Haemoglobin (HbA1c) in the Non-diabetes Population. (2024)
Journal Article
Stedman, M., Heald, A. H., Holland, D., Halsall, I., Green, L., Wu, P., Patel, K., Scargill, J., Gibson, M., Hanna, F. W. F., & Fryer, A. A. (in press). The Impact of Age and Sex on Fasting Plasma Glucose and Glycated Haemoglobin (HbA1c) in the Non-diabetes Population. Diabetes Therapy, https://doi.org/10.1007/s13300-024-01680-w

We previously reported sex differences in the distribution of glycated haemoglobin (HbA1c) for men/women aged < 50 years vs older individuals, with implications for delayed diabetes diagnosis. Here, we explored whether this pattern was also seen in m...

The link between age, sex, fasting plasma glucose and glycated haemoglobin (HbA 1c ) (2024)
Presentation / Conference Contribution
Stedman, M., Heald, A., Holland, D., Halsall, I., Green, L., Wu, P., Scargill, J., Hanna, F., Colclough, K., Gibson, M., & Fryer, A. The link between age, sex, fasting plasma glucose and glycated haemoglobin (HbA 1c ). Presented at 60th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Madrid, Spain

Using maternal glycosylated haemoglobin as well as glucose tolerance tests identified significantly more mothers with high birth weight in their offspring (2024)
Presentation / Conference Contribution
Wu, P., Stedman, M., Fryer, A., Green, L., Holland, D., Scargill, J., Pankaja, S., Christian, S., & Heald, A. Using maternal glycosylated haemoglobin as well as glucose tolerance tests identified significantly more mothers with high birth weight in their offspring. Presented at 60th EASD Annual Meeting of the European Association for the Study of Diabetes, Madrid, Spain

The OBS UK Dashboard: an interactive tool for representative trial site selection to facilitate equality and diversity in maternity research (2024)
Journal Article
Elsmore, A., Rai, T., Pallmann, P., Townson, J., Kotecha, S., Black, M., Sanders, J., Collis, R., Collins, P., Karunakaran, B., Wu, P., Bell, S., & Parry-Smith, W. (in press). The OBS UK Dashboard: an interactive tool for representative trial site selection to facilitate equality and diversity in maternity research. Trials, 25(1), Article 629. https://doi.org/10.1186/s13063-024-08487-x

Background: Obstetric Bleeding Study UK (OBS UK) (award ID: 152057) is a National Institute for Health and Care Research (NIHR)-funded stepped wedge cluster randomised controlled trial of a complex intervention for postpartum haemorrhage. This was de... Read More about The OBS UK Dashboard: an interactive tool for representative trial site selection to facilitate equality and diversity in maternity research.

O24 ACUTE KIDNEY INJURY IN PREGNANCY AND CARDIO-RENAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS (2024)
Presentation / Conference
Jeyaraman, D., Peiris, T. D. P., Alahmdi, H., Fish, R., Lambie, M., & Wu, P. (2024, September). O24 ACUTE KIDNEY INJURY IN PREGNANCY AND CARDIO-RENAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Presented at 30th Congress of the International Society of Hypertension, Cartegena de Indias, Colombia

Background and Objective: Acute kidney injury (AKI) is a common problem in pregnancy but adverse cardio-renal outcomes following AKI in pregnancy has not been systematically evaluated. We aimed to quantify the risk of adverse cardio-renal outcomes of... Read More about O24 ACUTE KIDNEY INJURY IN PREGNANCY AND CARDIO-RENAL OUTCOMES: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study (2024)
Presentation / Conference Contribution
Fisher, T., Archer, C., Bailey, J., Evans, J., Kessler, D. S., Kingstone, T., Petersen, I., Proctor, J., Shivji, N., Spruce, A., Silverwood, V., Smith, H., Turner, K., Wu, P., Yu, D., & Chew-Graham, C. (2024, March). Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study. Presented at BJGP Research & Publishing Conference, RCGP Headquarters in London, England, UK

Perinatal anxiety (PNA) occurs throughout the antenatal period or up to 1 year after childbirth, with a prevalence of 21%. To investigate if primary care records could be used to identify women at 'higher risk' of PNA. Mixed-methods approach using qu... Read More about Could primary care records be used to identify women at risk of perinatal anxiety? A mixed-methods study.

Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy. (2024)
Journal Article
Yang, M.-L., Hu, C.-Y., Lee, Y.-C., Chang, C.-C., Chen, Y.-C., Lee, P.-R., Su, B.-H., Chen, P.-C., Shiau, A.-L., Shieh, G.-S., Wu, C.-L., & Wu, P. (in press). Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy. Stem Cells Translational Medicine, Article szae039. https://doi.org/10.1093/stcltm/szae039

Oncolytic adenoviruses have emerged as a promising therapeutic approach for cancer therapy. However, systemic delivery of the viruses to metastatic tumors remains a major challenge. Mesenchymal stem cells (MSCs) possess tumor tropism property and can... Read More about Syngeneic mesenchymal stem cells loaded with telomerase-dependent oncolytic adenoviruses enhance anti-metastatic efficacy..