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Outputs (122)

The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system. (2024)
Journal Article
Talbot, B., Davies, S., Burman, J., Ritchie, A., Snelling, P., Lynch, S., Park, Y., Jones, B., Garvey, V., Jaure, A., Jardine, M., Perkovic, V., Gallagher, M., Brandwood, A., Kaur, N., & Knight, J. (in press). The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, https://doi.org/10.1177/08968608231209850

The global unmet need for kidney replacement therapy means that millions of people die every year as they cannot afford treatment. Peritoneal dialysis (PD) offers comparable survival to haemodialysis and is often more affordable, but one barrier to i... Read More about The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system..

Effects of Empagliflozin on Fluid Overload, Weight and Blood Pressure in Chronic Kidney Disease (2023)
Journal Article
Mayne, K. J., Staplin, N., Keane, D. F., Wanner, C., Brenner, S., Cejka, V., Stegbauer, J., Judge, P. K., Preiss, D., Emberson, J., Trinca, D., Dayanandan, R., Lee, R., Nolan, J., Omata, A., Green, J. B., Cherney, D. Z., Hooi, L. S., Pontremoli, R., Tuttle, K. R., …Herrington, W. G. (2023). Effects of Empagliflozin on Fluid Overload, Weight and Blood Pressure in Chronic Kidney Disease. Journal of the American Society of Nephrology, 35(2), 202-215. https://doi.org/10.1681/asn.0000000000000271

BACKGROUND: Chronic kidney disease (CKD) is associated with fluid excess which can be estimated by bioimpedance spectroscopy. We aimed to assess effects of sodium glucose co-transporter 2 inhibition on bioimpedance-derived “Fluid Overload” and adipos... Read More about Effects of Empagliflozin on Fluid Overload, Weight and Blood Pressure in Chronic Kidney Disease.

Providing environmentally sustainable nephrology care: focus in Low- and Middle-Income Countries. (2023)
Journal Article
Luyckx, V. A., Alasfar, S., Bajpai, D., Atwater, C. E., Knight, J., Talbot, B., Davies, S., & Niang, A. (2024). Providing environmentally sustainable nephrology care: focus in Low- and Middle-Income Countries. Kidney International, 105(2), 259-268. https://doi.org/10.1016/j.kint.2023.09.034

Healthcare on a global scale significantly contributes to carbon emissions, with high-income countries being the primary culprits. Within healthcare, dialysis plays a significant role as a major source of emissions. Low- and middle-income countries h... Read More about Providing environmentally sustainable nephrology care: focus in Low- and Middle-Income Countries..

Robust Joint Models of Albumin and All-Cause Mortality in Incident Peritoneal Dialysis Patients: A Dynamic Predictions Perspective Adjusting for Competing Risks (2023)
Presentation / Conference Contribution
Damgov, I., Kieser, M., Rutherford, P., Lambie, M., Davies, S. J., Wong, M. G., Pollock, C. A., Johnson, D. W., & Schmitt, C. P. (2023, November). Robust Joint Models of Albumin and All-Cause Mortality in Incident Peritoneal Dialysis Patients: A Dynamic Predictions Perspective Adjusting for Competing Risks. Poster presented at ASN Kidney Week, Philadelphia, PA, USA

Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis (2023)
Journal Article
Istanbuly, O., Belcher, J., Tabinor, M., Solis-Trapala, I., Lambie, M., & Davies, S. J. (in press). Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis. BMC Nephrology, 24(1), Article 312. https://doi.org/10.1186/s12882-023-03370-4

Background: Systemic inflammation, measured as circulating Interleukin-6 (IL-6) levels, is associated with cardiovascular and all-cause mortality in chronic kidney disease. However, this has not been convincingly demonstrated in a systematic review o... Read More about Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis.

Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion (2023)
Journal Article
Fotheringham, J., Solis-Trapala, I., Briggs, V., Lambie, M., McCullough, K., Dunn, L., Rawdin, A., Hill, H., Wailloo, A., Davies, S., & Wilkie, M. (2023). Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion. Kidney International Reports, 8(12), 2635-2645. https://doi.org/10.1016/j.ekir.2023.09.015

How patient, center, and insertion technique factors interact needs to be understood when designing peritoneal dialysis (PD) catheter insertion pathways. We undertook a prospective cohort study in 44 UK centers enrolling participants planned for firs... Read More about Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion.

An update on absolute and relative indications for dialysis treatment modalities (2023)
Journal Article
Lambie, M., & Davies, S. (2023). An update on absolute and relative indications for dialysis treatment modalities. Clinical Kidney Journal, 16(Supplement_1), i39-i47. https://doi.org/10.1093/ckj/sfad062

Background Choosing a dialysis modality is an important decision for people to make as their kidney failure progresses. In doing so, their options should be informed by any absolute or relative indications that may favour one modality over another. M... Read More about An update on absolute and relative indications for dialysis treatment modalities.

The Peritoneal Membrane and its Role in Peritoneal Dialysis. (2023)
Journal Article
Morelle, J., Lambie, M., Öberg, C. M., & Davies, S. (in press). The Peritoneal Membrane and its Role in Peritoneal Dialysis. Clinical Journal of the American Society of Nephrology, 10.2215/CJN.0000000000000282. https://doi.org/10.2215/CJN.0000000000000282

A healthy and functional peritoneal membrane is key to achieve sufficient ultrafiltration and to restore fluid balance, a major component of high-quality prescription in patients treated with peritoneal dialysis (PD). Variability in membrane function... Read More about The Peritoneal Membrane and its Role in Peritoneal Dialysis..