Outputs (2)

Pluripharmacological potential of Mascarene endemic plant leaf extracts (2022)
Journal Article
Rummun, N., Payne, B., Blom van Staden, A., Twilley, D., Houghton, B., Horrocks, P., Li, W.-W., Lall, N., Bahorun, T., & Neergheen, V. S. (2022). Pluripharmacological potential of Mascarene endemic plant leaf extracts. Biocatalysis and Agricultural Biotechnology, 47, Article 102572. https://doi.org/10.1016/j.bcab.2022.102572

Tropical forests of the islands of the West Indian Ocean region, have a rich and diverse collection of unique plants containing a multitude of chemical scaffolds that can potentially be developed into medicinal agents. Till date, endemic plants from... Read More about Pluripharmacological potential of Mascarene endemic plant leaf extracts.

Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger. (2022)
Journal Article
Luo, J., Mobley, R., Woodfine, S., Drijfhout, F., Horrocks, P., Ren, X., & Li, W. (2022). Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger. Applied Microbiology and Biotechnology, 106, 2433-2444. https://doi.org/10.1007/s00253-022-11888-0

Artemisinin is a component part of current frontline medicines for the treatment of malaria. The aim of this study is to make analogues of artemisinin using microbial transformation and evaluate their in vitro antimalarial activity. A panel of microo... Read More about Biotransformation of artemisinin to a novel derivative via ring rearrangement by Aspergillus niger..