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Outputs (302)

Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework (2016)
Journal Article
(2016). Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework. PloS one, e0150205 - ?. https://doi.org/10.1371/journal.pone.0150205

We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conf... Read More about Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework.

Telling the patients about diagnosis and outcome of schizophrenia: what, when and how? (2016)
Journal Article
Farooq, S., Naeem, F., & Singh, S. P. (2016). Telling the patients about diagnosis and outcome of schizophrenia: what, when and how?. Early Intervention in Psychiatry, 10(2), 101-102. https://doi.org/10.1111/eip.12310

Informing patients about the diagnosis and outcome of a serious disorder is a key clinical skill and a basic ethical duty in a therapeutic encounter. How clinicians meet this challenge in schizophrenia, which is arguably one of the most serious menta... Read More about Telling the patients about diagnosis and outcome of schizophrenia: what, when and how?.

Changes in arterial access site and association with mortality in the United Kingdom: observations from a national percutaneous coronary intervention database (2016)
Journal Article
Mamas, M. A., Nolan, J., de Belder, M. A., Zaman, A., Kinnaird, T., Curzen, N., …Kontopantelis, E. (2016). Changes in arterial access site and association with mortality in the United Kingdom: observations from a national percutaneous coronary intervention database. Circulation, 133(17), 1655-1667. https://doi.org/10.1161/CIRCULATIONAHA.115.018083

Background The transradial access (TRA) site has become the default access site for PCI in the UK with randomized trials and national registry data showing reductions in mortality associated with TRA utilization. This study evaluates regional changes... Read More about Changes in arterial access site and association with mortality in the United Kingdom: observations from a national percutaneous coronary intervention database.

Cognitive Behaviour Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study (2016)
Journal Article
Farooq. (2016). Cognitive Behaviour Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study. Schizophrenia Research, 69-74. https://doi.org/10.1016/j.schres.2016.03.003

Availability of Cognitive Behavior Therapy for psychosis (CBTp) is limited in spite of strong evidence base. The purpose of this study was to determine the feasibility of a CBTp based Guided Self-help (CBTp-GSH) in comparison to Treatment As Usual (T... Read More about Cognitive Behaviour Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study.

A qualitative study exploring midlife women's stages of change from domestic violence towards freedom. (2016)
Journal Article
Keeling. (2016). A qualitative study exploring midlife women's stages of change from domestic violence towards freedom. BMC Women's Health, 13 - ?. https://doi.org/10.1186/s12905-016-0291-9

BACKGROUND: Domestic Violence (DV) remains a significant global health problem for women in contemporary society. Existing literature on midlife women's experiences of domestic violence is limited and focuses on health implications. Leaving a violent... Read More about A qualitative study exploring midlife women's stages of change from domestic violence towards freedom..

Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis. (2016)
Journal Article
(2016). Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis. British journal of cancer, 623 - 630. https://doi.org/10.1038/bjc.2016.28

BACKGROUND: Risk-stratified management of fever with neutropenia (FN), allows intensive management of high-risk cases and early discharge of low-risk cases. No single, internationally validated, prediction model of the risk of adverse outcomes exists... Read More about Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis..

Clinical management following self-harm in a UK-wide primary care cohort (2016)
Journal Article
Chew-Graham. (2016). Clinical management following self-harm in a UK-wide primary care cohort. Journal of Affective Disorders, 182-188. https://doi.org/10.1016/j.jad.2016.03.013

Background Little is known about the clinical management of patients in primary care following self-harm. Methods A descriptive cohort study using data from 684 UK general practices that contributed to the Clinical Practice Research Datalink (CP... Read More about Clinical management following self-harm in a UK-wide primary care cohort.

Weighted cumulative exposure models helped identify an association between early knee-pain consultations and future knee OA diagnosis (2016)
Journal Article
Yu, D., Peat, G., Bedson, J., Edwards, J. J., Turkiewicz, A., & Jordan, K. P. (2016). Weighted cumulative exposure models helped identify an association between early knee-pain consultations and future knee OA diagnosis. Journal of Clinical Epidemiology, 218-228. https://doi.org/10.1016/j.jclinepi.2016.02.025

Objective To establish the association between prior knee-pain consultations and early diagnosis of knee osteoarthritis (OA) by weighted cumulative exposure (WCE) models. Study Design and Setting Data were from an electronic health care record (... Read More about Weighted cumulative exposure models helped identify an association between early knee-pain consultations and future knee OA diagnosis.

An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain (2016)
Journal Article
Jowett, S., Nicholls, E., Al-Janabi, H., Keeley, T., Coast, J., & Foster, N. (2016). An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain. Health and Quality of Life Outcomes, 36 -?. https://doi.org/10.1186/s12955-016-0430-x

BACKGROUND: The ICECAP measures potentially offer a broader assessment of quality of life and well-being, in comparison to measures routinely used in economic evaluation, such as the EQ-5D-3 L. This broader assessment may allow measurement of the ful... Read More about An analysis of the complementarity of ICECAP-A and EQ-5D-3 L in an adult population of patients with knee pain.